242 related articles for article (PubMed ID: 31209056)
1. Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar F; Findlay JE; Carfray G; Allcock RW; Jiang Z; Moore C; Muir AL; Lannoy M; Fertig BA; Mai D; Day JP; Bolger G; Baillie GS; Schwiebert E; Klussmann E; Pyne NJ; Ong ACM; Bowers K; Adam JM; Adams DR; Houslay MD; Henderson DJP
Proc Natl Acad Sci U S A; 2019 Jul; 116(27):13320-13329. PubMed ID: 31209056
[TBL] [Abstract][Full Text] [Related]
2. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy.
Wang L; Burmeister BT; Johnson KR; Baillie GS; Karginov AV; Skidgel RA; O'Bryan JP; Carnegie GK
Cell Signal; 2015 May; 27(5):908-22. PubMed ID: 25683917
[TBL] [Abstract][Full Text] [Related]
3. Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA).
Collins DM; Murdoch H; Dunlop AJ; Charych E; Baillie GS; Wang Q; Herberg FW; Brandon N; Prinz A; Houslay MD
Cell Signal; 2008 Dec; 20(12):2356-69. PubMed ID: 18845247
[TBL] [Abstract][Full Text] [Related]
4. Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression.
Sheppard CL; Lee LC; Hill EV; Henderson DJ; Anthony DF; Houslay DM; Yalla KC; Cairns LS; Dunlop AJ; Baillie GS; Huston E; Houslay MD
Cell Signal; 2014 Sep; 26(9):1958-74. PubMed ID: 24815749
[TBL] [Abstract][Full Text] [Related]
5. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
MacKenzie SJ; Baillie GS; McPhee I; MacKenzie C; Seamons R; McSorley T; Millen J; Beard MB; van Heeke G; Houslay MD
Br J Pharmacol; 2002 Jun; 136(3):421-33. PubMed ID: 12023945
[TBL] [Abstract][Full Text] [Related]
6. Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK.
Li X; Vadrevu S; Dunlop A; Day J; Advant N; Troeger J; Klussmann E; Jaffrey E; Hay RT; Adams DR; Houslay MD; Baillie GS
Biochem J; 2010 Apr; 428(1):55-65. PubMed ID: 20196770
[TBL] [Abstract][Full Text] [Related]
7. Lixazinone stimulates mitogenesis of Madin-Darby canine kidney cells.
Cheng J; Thompson MA; Walker HJ; Gray CE; Warner GM; Zhou W; Grande JP
Exp Biol Med (Maywood); 2006 Mar; 231(3):288-95. PubMed ID: 16514175
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-induced remodelling of PDE4 isoform expression and cAMP handling in human pulmonary artery smooth muscle cells.
Millen J; MacLean MR; Houslay MD
Eur J Cell Biol; 2006 Jul; 85(7):679-91. PubMed ID: 16458997
[TBL] [Abstract][Full Text] [Related]
9. Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4.
Vinogradova TM; Sirenko S; Lukyanenko YO; Yang D; Tarasov KV; Lyashkov AE; Varghese NJ; Li Y; Chakir K; Ziman B; Lakatta EG
Circ Arrhythm Electrophysiol; 2018 Jun; 11(6):e005896. PubMed ID: 29880528
[TBL] [Abstract][Full Text] [Related]
10. The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways.
Houslay MD; Baillie GS
Biochem Soc Trans; 2003 Dec; 31(Pt 6):1186-90. PubMed ID: 14641023
[TBL] [Abstract][Full Text] [Related]
11. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
Zhu B; Kelly J; Vemavarapu L; Thompson WJ; Strada SJ
Biochem Pharmacol; 2004 Aug; 68(3):479-91. PubMed ID: 15242814
[TBL] [Abstract][Full Text] [Related]
12. Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners.
Houslay KF; Christian F; MacLeod R; Adams DR; Houslay MD; Baillie GS
Biochem J; 2017 Feb; 474(4):597-609. PubMed ID: 27993970
[TBL] [Abstract][Full Text] [Related]
13. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.
Havekes R; Park AJ; Tolentino RE; Bruinenberg VM; Tudor JC; Lee Y; Hansen RT; Guercio LA; Linton E; Neves-Zaph SR; Meerlo P; Baillie GS; Houslay MD; Abel T
J Neurosci; 2016 Aug; 36(34):8936-46. PubMed ID: 27559174
[TBL] [Abstract][Full Text] [Related]
14. Reciprocal regulation of calcium dependent and calcium independent cyclic AMP hydrolysis by protein phosphorylation.
Ang KL; Antoni FA
J Neurochem; 2002 May; 81(3):422-33. PubMed ID: 12065651
[TBL] [Abstract][Full Text] [Related]
15. Modulation of signaling through GPCR-cAMP-PKA pathways by PDE4 depends on stimulus intensity: Possible implications for the pathogenesis of acrodysostosis without hormone resistance.
Motte E; Le Stunff C; Briet C; Dumaz N; Silve C
Mol Cell Endocrinol; 2017 Feb; 442():1-11. PubMed ID: 27908835
[TBL] [Abstract][Full Text] [Related]
16. Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice.
Wang ZZ; Yang WX; Zhang Y; Zhao N; Zhang YZ; Liu YQ; Xu Y; Wilson SP; O'Donnell JM; Zhang HT; Li YF
Sci Rep; 2015 Jul; 5():11332. PubMed ID: 26161529
[TBL] [Abstract][Full Text] [Related]
17. Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains.
Bolger GB; Dunlop AJ; Meng D; Day JP; Klussmann E; Baillie GS; Adams DR; Houslay MD
Cell Signal; 2015 Apr; 27(4):756-69. PubMed ID: 25546709
[TBL] [Abstract][Full Text] [Related]
18. Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types.
Paes D; Hermans S; van den Hove D; Vanmierlo T; Prickaerts J; Carlier A
Biophys J; 2022 Jul; 121(14):2693-2711. PubMed ID: 35717559
[TBL] [Abstract][Full Text] [Related]
19. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
Houslay MD; Baillie GS; Maurice DH
Circ Res; 2007 Apr; 100(7):950-66. PubMed ID: 17431197
[TBL] [Abstract][Full Text] [Related]
20. PDE4 associates with different scaffolding proteins: modulating interactions as treatment for certain diseases.
McCahill AC; Huston E; Li X; Houslay MD
Handb Exp Pharmacol; 2008; (186):125-66. PubMed ID: 18491051
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]