BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 31215251)

  • 1. Everolimus for the treatment of advanced pancreatic ductal adenocarcinoma (PDAC).
    Babiker HM; Karass M; Recio-Boiles A; Chandana SR; McBride A; Mahadevan D
    Expert Opin Investig Drugs; 2019 Jul; 28(7):583-592. PubMed ID: 31215251
    [No Abstract]   [Full Text] [Related]  

  • 2. UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism.
    Dando I; Pacchiana R; Pozza ED; Cataldo I; Bruno S; Conti P; Cordani M; Grimaldi A; Butera G; Caraglia M; Scarpa A; Palmieri M; Donadelli M
    Free Radic Biol Med; 2017 Dec; 113():176-189. PubMed ID: 28962872
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma.
    Wong MH; Xue A; Baxter RC; Pavlakis N; Smith RC
    Neoplasia; 2016 Jul; 18(7):425-35. PubMed ID: 27435925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC).
    Chandana S; Babiker HM; Mahadevan D
    Expert Opin Investig Drugs; 2019 Feb; 28(2):161-177. PubMed ID: 30539678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycogen synthase kinase-3β: a novel therapeutic target for pancreatic cancer.
    Ding L; Billadeau DD
    Expert Opin Ther Targets; 2020 May; 24(5):417-426. PubMed ID: 32178549
    [No Abstract]   [Full Text] [Related]  

  • 6. mTOR is a promising therapeutical target in a subpopulation of pancreatic adenocarcinoma.
    Utomo WK; Narayanan V; Biermann K; van Eijck CH; Bruno MJ; Peppelenbosch MP; Braat H
    Cancer Lett; 2014 May; 346(2):309-17. PubMed ID: 24467966
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models.
    Diersch S; Wenzel P; Szameitat M; Eser P; Paul MC; Seidler B; Eser S; Messer M; Reichert M; Pagel P; Esposito I; Schmid RM; Saur D; Schneider G
    Oncotarget; 2013 Feb; 4(2):277-88. PubMed ID: 23470560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.
    Wei F; Liu Y; Bellail AC; Olson JJ; Sun SY; Lu G; Ding L; Yuan C; Wang G; Hao C
    Cancer Lett; 2012 Sep; 322(1):58-69. PubMed ID: 22342683
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The isoflavone puerarin exerts anti-tumor activity in pancreatic ductal adenocarcinoma by suppressing mTOR-mediated glucose metabolism.
    Zhu H; Xiao Y; Guo H; Guo Y; Huang Y; Shan Y; Bai Y; Lin X; Lu H
    Aging (Albany NY); 2021 Dec; 13(23):25089-25105. PubMed ID: 34863080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The efficacy of a novel, dual PI3K/mTOR inhibitor NVP-BEZ235 to enhance chemotherapy and antiangiogenic response in pancreatic cancer.
    Awasthi N; Yen PL; Schwarz MA; Schwarz RE
    J Cell Biochem; 2012 Mar; 113(3):784-91. PubMed ID: 22020918
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
    Nagathihalli NS; Castellanos JA; Shi C; Beesetty Y; Reyzer ML; Caprioli R; Chen X; Walsh AJ; Skala MC; Moses HL; Merchant NB
    Gastroenterology; 2015 Dec; 149(7):1932-1943.e9. PubMed ID: 26255562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.
    Ning C; Liang M; Liu S; Wang G; Edwards H; Xia Y; Polin L; Dyson G; Taub JW; Mohammad RM; Azmi AS; Zhao L; Ge Y
    Oncotarget; 2017 Jul; 8(27):44295-44311. PubMed ID: 28574828
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.
    Soares HP; Ni Y; Kisfalvi K; Sinnett-Smith J; Rozengurt E
    PLoS One; 2013; 8(2):e57289. PubMed ID: 23437362
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study.
    Joka M; Boeck S; Zech CJ; Seufferlein T; Wichert Gv; Licht T; Krause A; Jauch KW; Heinemann V; Bruns CJ
    Anticancer Drugs; 2014 Oct; 25(9):1095-101. PubMed ID: 25029236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer.
    Pan CH; Otsuka Y; Sridharan B; Woo M; Leiton CV; Babu S; Torrente Gonçalves M; Kawalerski RR; K Bai JD; Chang DK; Biankin AV; Scampavia L; Spicer T; Escobar-Hoyos LF; Shroyer KR
    Mol Oncol; 2020 Aug; 14(8):1800-1816. PubMed ID: 32533886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase II Study of BEZ235 versus Everolimus in Patients with Mammalian Target of Rapamycin Inhibitor-Naïve Advanced Pancreatic Neuroendocrine Tumors.
    Salazar R; Garcia-Carbonero R; Libutti SK; Hendifar AE; Custodio A; Guimbaud R; Lombard-Bohas C; Ricci S; Klümpen HJ; Capdevila J; Reed N; Walenkamp A; Grande E; Safina S; Meyer T; Kong O; Salomon H; Tavorath R; Yao JC
    Oncologist; 2018 Jul; 23(7):766-e90. PubMed ID: 29242283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.
    Javle MM; Shroff RT; Xiong H; Varadhachary GA; Fogelman D; Reddy SA; Davis D; Zhang Y; Wolff RA; Abbruzzese JL
    BMC Cancer; 2010 Jul; 10():368. PubMed ID: 20630061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting apoptosis pathways in pancreatic cancer.
    Arlt A; Müerköster SS; Schäfer H
    Cancer Lett; 2013 May; 332(2):346-58. PubMed ID: 21078544
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prospects of targeting PI3K/AKT/mTOR pathway in pancreatic cancer.
    Mortazavi M; Moosavi F; Martini M; Giovannetti E; Firuzi O
    Crit Rev Oncol Hematol; 2022 Aug; 176():103749. PubMed ID: 35728737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice.
    Pawaskar DK; Straubinger RM; Fetterly GJ; Hylander BH; Repasky EA; Ma WW; Jusko WJ
    Cancer Chemother Pharmacol; 2013 May; 71(5):1231-40. PubMed ID: 23455452
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.