These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 3121855)

  • 21. Identification and biochemical properties of 10-formyldihydrofolate, a novel folate found in methotrexate-treated cells.
    Baram J; Chabner BA; Drake JC; Fitzhugh AL; Sholar PW; Allegra CJ
    J Biol Chem; 1988 May; 263(15):7105-11. PubMed ID: 3366769
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design and synthesis of inhibitors of folate-dependent enzymes as antitumor agents.
    Taylor EC
    Adv Exp Med Biol; 1993; 338():387-408. PubMed ID: 8304144
    [No Abstract]   [Full Text] [Related]  

  • 23. Synthesis and biological activity of 5,11-methylenetetrahydro-5- deazahomofolic acid.
    Gangjee A; Donkor IO; Kisliuk RL; Gaumont Y; Thorndike J
    J Med Chem; 1991 Feb; 34(2):611-6. PubMed ID: 1995884
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel nonclassical inhibitors of glycinamide ribonucleotide formyltransferase: 10-formyl and 10-hydroxymethyl derivatives of 5,8,10-trideazapteroic acid.
    Liu L; Nair MG; Kisliuk RL
    J Mol Recognit; 1996; 9(2):169-74. PubMed ID: 8877810
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM.
    Pizzorno G; Moroson BA; Cashmore AR; Russello O; Mayer JR; Galivan J; Bunni MA; Priest DG; Beardsley GP
    Cancer Res; 1995 Feb; 55(3):566-73. PubMed ID: 7834626
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities.
    Gangjee A; Patel J; Kisliuk RL; Gaumont Y
    J Med Chem; 1992 Oct; 35(20):3678-85. PubMed ID: 1433179
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.
    Patil SD; Jones C; Nair MG; Galivan J; Maley F; Kisliuk RL; Gaumont Y; Duch D; Ferone R
    J Med Chem; 1989 Jun; 32(6):1284-9. PubMed ID: 2542557
    [TBL] [Abstract][Full Text] [Related]  

  • 28. N-[4-[[(3,4-dihydro-4-oxo-1,2,3-benzotriazin-6- yl)methyl]amino]benzoyl]-L-glutamic acid, a novel A-ring analogue of 2-desamino-5,8-dideazafolic acid.
    Rosowsky A; Forsch RA; Moran RG
    J Med Chem; 1992 Jul; 35(14):2626-30. PubMed ID: 1635061
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis of 5,11-methenyltetrahydrohomofolate and its antifolate activity in vitro.
    Caperelli CA; Domanico P; Benkovic SJ
    J Med Chem; 1981 Sep; 24(9):1086-8. PubMed ID: 7288824
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF).
    Nair MG; Nanavati NT; Nair IG; Kisliuk RL; Gaumont Y; Hsiao MC; Kalman TI
    J Med Chem; 1986 Sep; 29(9):1754-60. PubMed ID: 3091832
    [TBL] [Abstract][Full Text] [Related]  

  • 31. New synthesis of N-[4-[[(2-amino-4(3H)-oxopyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives.
    Temple C; Kussner CL; Rose JD; Smithers DL; Bennett LL; Montgomery JA
    J Med Chem; 1981 Oct; 24(10):1254-8. PubMed ID: 6948961
    [TBL] [Abstract][Full Text] [Related]  

  • 32. N10-substituted 5,8-dideazafolate inhibitors of glycinamide ribonucleotide transformylase.
    Caperelli CA
    J Med Chem; 1987 Jul; 30(7):1254-6. PubMed ID: 3599031
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase.
    Boger DL; Labroli MA; Marsilje TH; Jin Q; Hedrick MP; Baker SJ; Shim JH; Benkovic SJ
    Bioorg Med Chem; 2000 May; 8(5):1075-86. PubMed ID: 10882019
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of chicken liver 5-aminoimidazole-4-carboxamide ribonucleotide transformylase by 5,8-dideaza analogues of folic acid.
    Mueller WT; Smith GK; Benkovic SJ; Hynes JB
    Biochem Pharmacol; 1988 Feb; 37(3):449-51. PubMed ID: 3337744
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
    Galivan J; Nimec Z; Rhee M; Boschelli D; Oronsky AL; Kerwar SS
    Cancer Res; 1988 May; 48(9):2421-5. PubMed ID: 2965613
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Folate analogues altered in the C9-N10 bridge region: N10-Toxylisohomofolic acid and N10-Toxylisohomoaminopterin.
    Nair MG; O'Neal PC; Baugh CM; Kisliuk RL; Gaumont Y; Rodman M
    J Med Chem; 1978 Jul; 21(7):673-7. PubMed ID: 97383
    [No Abstract]   [Full Text] [Related]  

  • 37. Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues.
    Singh SK; Dev IK; Duch DS; Ferone R; Smith GK; Freisheim JH; Hynes JB
    J Med Chem; 1991 Feb; 34(2):606-10. PubMed ID: 1995883
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate.
    Slieker LJ; Benkovic SJ
    Mol Pharmacol; 1984 Mar; 25(2):294-302. PubMed ID: 6700575
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase.
    Baldwin SW; Tse A; Gossett LS; Taylor EC; Rosowsky A; Shih C; Moran RG
    Biochemistry; 1991 Feb; 30(7):1997-2006. PubMed ID: 1993209
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of bridge region variation on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines.
    Gangjee A; Devraj R; McGuire JJ; Kisliuk RL
    J Med Chem; 1995 Sep; 38(19):3798-805. PubMed ID: 7562910
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.