BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 31225475)

  • 1. Calling RNF168 to action.
    Nowsheen S; Lou Z
    Cell Stress; 2018 May; 2(5):113-114. PubMed ID: 31225475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage.
    Nowsheen S; Aziz K; Aziz A; Deng M; Qin B; Luo K; Jeganathan KB; Zhang H; Liu T; Yu J; Deng Y; Yuan J; Ding W; van Deursen JM; Lou Z
    Nat Cell Biol; 2018 Apr; 20(4):455-464. PubMed ID: 29581593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
    Thorslund T; Ripplinger A; Hoffmann S; Wild T; Uckelmann M; Villumsen B; Narita T; Sixma TK; Choudhary C; Bekker-Jensen S; Mailand N
    Nature; 2015 Nov; 527(7578):389-93. PubMed ID: 26503038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.
    Mattiroli F; Vissers JH; van Dijk WJ; Ikpa P; Citterio E; Vermeulen W; Marteijn JA; Sixma TK
    Cell; 2012 Sep; 150(6):1182-95. PubMed ID: 22980979
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168.
    Kocyłowski MK; Rey AJ; Stewart GS; Halazonetis TD
    Cell Cycle; 2015; 14(11):1748-58. PubMed ID: 25695757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites.
    Yan J; Jetten AM
    Cancer Lett; 2008 Nov; 271(2):179-90. PubMed ID: 18550271
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
    Galanty Y; Belotserkovskaya R; Coates J; Polo S; Miller KM; Jackson SP
    Nature; 2009 Dec; 462(7275):935-9. PubMed ID: 20016603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
    Hodge CD; Ismail IH; Edwards RA; Hura GL; Xiao AT; Tainer JA; Hendzel MJ; Glover JN
    J Biol Chem; 2016 Apr; 291(18):9396-410. PubMed ID: 26903517
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.
    Bohgaki T; Bohgaki M; Cardoso R; Panier S; Zeegers D; Li L; Stewart GS; Sanchez O; Hande MP; Durocher D; Hakem A; Hakem R
    PLoS Genet; 2011 Apr; 7(4):e1001381. PubMed ID: 21552324
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining.
    Chen BR; Wang Y; Shen ZJ; Bennett A; Hindi I; Tyler JK; Sleckman BP
    DNA Repair (Amst); 2021 Dec; 108():103217. PubMed ID: 34481157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.
    Mosbech A; Lukas C; Bekker-Jensen S; Mailand N
    J Biol Chem; 2013 Jun; 288(23):16579-16587. PubMed ID: 23615962
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
    Doil C; Mailand N; Bekker-Jensen S; Menard P; Larsen DH; Pepperkok R; Ellenberg J; Panier S; Durocher D; Bartek J; Lukas J; Lukas C
    Cell; 2009 Feb; 136(3):435-46. PubMed ID: 19203579
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.
    Zhao H; Zhu M; Dou G; Zhao H; Zhu B; Li J; Liao J; Xu X
    Cell Cycle; 2014; 13(11):1777-87. PubMed ID: 24732096
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.
    Nakada S
    J Radiat Res; 2016 Aug; 57 Suppl 1(Suppl 1):i33-i40. PubMed ID: 26983989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.
    Mandemaker IK; van Cuijk L; Janssens RC; Lans H; Bezstarosti K; Hoeijmakers JH; Demmers JA; Vermeulen W; Marteijn JA
    Sci Rep; 2017 Nov; 7(1):15353. PubMed ID: 29127375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells.
    Morris C; Tomimatsu N; Burma S; Jalinot P
    Cancer Res; 2016 Oct; 76(20):6054-6065. PubMed ID: 27550454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crosstalk between histone modifications during the DNA damage response.
    van Attikum H; Gasser SM
    Trends Cell Biol; 2009 May; 19(5):207-17. PubMed ID: 19342239
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling.
    Smeenk G; Wiegant WW; Marteijn JA; Luijsterburg MS; Sroczynski N; Costelloe T; Romeijn RJ; Pastink A; Mailand N; Vermeulen W; van Attikum H
    J Cell Sci; 2013 Feb; 126(Pt 4):889-903. PubMed ID: 23264744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RNF8-ubiquitinated KMT5A is required for RNF168-induced H2A ubiquitination in response to DNA damage.
    Lu X; Xu M; Zhu Q; Zhang J; Liu G; Bao Y; Gu L; Tian Y; Wen H; Zhu WG
    FASEB J; 2021 Apr; 35(4):e21326. PubMed ID: 33710666
    [TBL] [Abstract][Full Text] [Related]  

  • 20. USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.
    Sharma N; Zhu Q; Wani G; He J; Wang QE; Wani AA
    Cell Cycle; 2014; 13(1):106-14. PubMed ID: 24196443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.