186 related articles for article (PubMed ID: 31244225)
1. Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry (ssHDX-MS) of Lyophilized Poly-d,l-Alanine.
Kammari R; Topp EM
Mol Pharm; 2019 Jul; 16(7):2935-2946. PubMed ID: 31244225
[TBL] [Abstract][Full Text] [Related]
2. Prehydration and the Reversibility of Solid-State Hydrogen-Deuterium Exchange.
Kammari R; Topp EM
Mol Pharm; 2020 Sep; 17(9):3541-3552. PubMed ID: 32786954
[TBL] [Abstract][Full Text] [Related]
3. Predicting protein aggregation during storage in lyophilized solids using solid state amide hydrogen/deuterium exchange with mass spectrometric analysis (ssHDX-MS).
Moorthy BS; Schultz SG; Kim SG; Topp EM
Mol Pharm; 2014 Jun; 11(6):1869-79. PubMed ID: 24816133
[TBL] [Abstract][Full Text] [Related]
4. Optimizing the Formulation and Lyophilization Process for a Fragment Antigen Binding (Fab) Protein Using Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry (ssHDX-MS).
Kumar L; Chandrababu KB; Balakrishnan SM; Allmendinger A; Walters B; Zarraga IE; Chang DP; Nayak P; Topp EM
Mol Pharm; 2019 Nov; 16(11):4485-4495. PubMed ID: 31568722
[TBL] [Abstract][Full Text] [Related]
5. Effects of Secondary Structure on Solid-State Hydrogen-Deuterium Exchange in Model α-Helix and β-Sheet Peptides.
Kammari R; Topp EM
Mol Pharm; 2020 Sep; 17(9):3501-3512. PubMed ID: 32672982
[TBL] [Abstract][Full Text] [Related]
6. Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS).
Wilson NE; Topp EM; Zhou QT
Int J Pharm; 2019 Aug; 567():118470. PubMed ID: 31252148
[TBL] [Abstract][Full Text] [Related]
7. Effects of Drying Process on an IgG1 Monoclonal Antibody Using Solid-State Hydrogen Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS).
Moussa EM; Wilson NE; Zhou QT; Singh SK; Nema S; Topp EM
Pharm Res; 2018 Jan; 35(1):12. PubMed ID: 29299701
[TBL] [Abstract][Full Text] [Related]
8. Probing the Conformation of an IgG1 Monoclonal Antibody in Lyophilized Solids Using Solid-State Hydrogen-Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS).
Moussa EM; Singh SK; Kimmel M; Nema S; Topp EM
Mol Pharm; 2018 Feb; 15(2):356-368. PubMed ID: 29355022
[TBL] [Abstract][Full Text] [Related]
9. Photolytic Labeling To Quantify Peptide-Water Interactions in Lyophilized Solids.
Chen Y; Topp EM
Mol Pharm; 2019 Mar; 16(3):1053-1064. PubMed ID: 30721080
[TBL] [Abstract][Full Text] [Related]
10. Effects of temperature and relative humidity in D
Tukra R; Gardner S; Topp EM
Int J Pharm; 2021 Mar; 596():120263. PubMed ID: 33486024
[TBL] [Abstract][Full Text] [Related]
11. Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying.
Wilson NE; Mutukuri TT; Zemlyanov DY; Taylor LS; Topp EM; Zhou QT
Pharm Res; 2019 Dec; 37(1):14. PubMed ID: 31873808
[TBL] [Abstract][Full Text] [Related]
12. Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry: Correlation of Deuterium Uptake and Long-Term Stability of Lyophilized Monoclonal Antibody Formulations.
Moorthy BS; Zarraga IE; Kumar L; Walters BT; Goldbach P; Topp EM; Allmendinger A
Mol Pharm; 2018 Jan; 15(1):1-11. PubMed ID: 29182876
[TBL] [Abstract][Full Text] [Related]
13. Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry.
Wood VE; Kellerman MA; Groves K; Quaglia M; Topp EM; Matejtschuk P; Dalby PA
Mol Pharm; 2024 Apr; 21(4):1965-1976. PubMed ID: 38516985
[TBL] [Abstract][Full Text] [Related]
14. Effects of ionic interactions on protein stability prediction using solid-state hydrogen deuterium exchange with mass spectrometry (ssHDX-MS).
AbouGhaly MHH; Du J; Patel SM; Topp EM
Int J Pharm; 2019 Sep; 568():118512. PubMed ID: 31301464
[TBL] [Abstract][Full Text] [Related]
15. Effects of excipients on protein conformation in lyophilized solids by hydrogen/deuterium exchange mass spectrometry.
Li Y; Williams TD; Topp EM
Pharm Res; 2008 Feb; 25(2):259-67. PubMed ID: 17597380
[TBL] [Abstract][Full Text] [Related]
16. Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids.
Kabaria SR; Mangion I; Makarov AA; Pirrone GF
Anal Chim Acta; 2019 Apr; 1054():114-121. PubMed ID: 30712581
[TBL] [Abstract][Full Text] [Related]
17. Effects of drying method and excipient on the structure and physical stability of protein solids: Freeze drying vs. spray freeze drying.
Mutukuri TT; Wilson NE; Taylor LS; Topp EM; Zhou QT
Int J Pharm; 2021 Feb; 594():120169. PubMed ID: 33333176
[TBL] [Abstract][Full Text] [Related]
18. Localized hydration in lyophilized myoglobin by hydrogen-deuterium exchange mass spectrometry. 2. Exchange kinetics.
Sophocleous AM; Topp EM
Mol Pharm; 2012 Apr; 9(4):727-33. PubMed ID: 22352990
[TBL] [Abstract][Full Text] [Related]
19. Stability of antibody drug conjugate formulations evaluated using solid-state hydrogen-deuterium exchange mass spectrometry.
Cho E; Mayhugh BM; Srinivasan JM; Sacha GA; Nail SL; Topp EM
J Pharm Sci; 2021 Jun; 110(6):2379-2385. PubMed ID: 33711346
[TBL] [Abstract][Full Text] [Related]
20. Colyophilized Sugar-Polymer Dispersions for Enhanced Processing and Storage Stability.
Giannachi C; Allen E; Egan G; Vucen S; Crean A
Mol Pharm; 2024 Jun; 21(6):3017-3026. PubMed ID: 38758116
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
