254 related articles for article (PubMed ID: 31247512)
1. Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling.
Kowatsch C; Woolley RE; Kinnebrew M; Rohatgi R; Siebold C
Curr Opin Struct Biol; 2019 Aug; 57():204-214. PubMed ID: 31247512
[TBL] [Abstract][Full Text] [Related]
2. The interplay of Patched, Smoothened and cholesterol in Hedgehog signaling.
Hu A; Song BL
Curr Opin Cell Biol; 2019 Dec; 61():31-38. PubMed ID: 31369952
[TBL] [Abstract][Full Text] [Related]
3. Cholesterol access in cellular membranes controls Hedgehog signaling.
Radhakrishnan A; Rohatgi R; Siebold C
Nat Chem Biol; 2020 Dec; 16(12):1303-1313. PubMed ID: 33199907
[TBL] [Abstract][Full Text] [Related]
4. Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.
Deshpande I; Liang J; Hedeen D; Roberts KJ; Zhang Y; Ha B; Latorraca NR; Faust B; Dror RO; Beachy PA; Myers BR; Manglik A
Nature; 2019 Jul; 571(7764):284-288. PubMed ID: 31263273
[TBL] [Abstract][Full Text] [Related]
5. Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.
Xiao X; Tang JJ; Peng C; Wang Y; Fu L; Qiu ZP; Xiong Y; Yang LF; Cui HW; He XL; Yin L; Qi W; Wong CC; Zhao Y; Li BL; Qiu WW; Song BL
Mol Cell; 2017 Apr; 66(1):154-162.e10. PubMed ID: 28344083
[TBL] [Abstract][Full Text] [Related]
6. Patching the gaps in Hedgehog signalling.
Rohatgi R; Scott MP
Nat Cell Biol; 2007 Sep; 9(9):1005-9. PubMed ID: 17762891
[TBL] [Abstract][Full Text] [Related]
7. Sterol regulation of developmental and oncogenic Hedgehog signaling.
Daggubati V; Raleigh DR; Sever N
Biochem Pharmacol; 2022 Feb; 196():114647. PubMed ID: 34111427
[TBL] [Abstract][Full Text] [Related]
8. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
[TBL] [Abstract][Full Text] [Related]
9. Structures of human Patched and its complex with native palmitoylated sonic hedgehog.
Qi X; Schmiege P; Coutavas E; Wang J; Li X
Nature; 2018 Aug; 560(7716):128-132. PubMed ID: 29995851
[TBL] [Abstract][Full Text] [Related]
10. Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in
Zhang J; Liu Y; Wang C; Vander Kooi CW; Jia J
Sci Signal; 2023 Oct; 16(807):eadd6834. PubMed ID: 37847757
[TBL] [Abstract][Full Text] [Related]
11. Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction.
Shi D; Lv X; Zhang Z; Yang X; Zhou Z; Zhang L; Zhao Y
J Biol Chem; 2013 May; 288(18):12605-14. PubMed ID: 23532857
[TBL] [Abstract][Full Text] [Related]
12. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
[TBL] [Abstract][Full Text] [Related]
13. Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Huang P; Nedelcu D; Watanabe M; Jao C; Kim Y; Liu J; Salic A
Cell; 2016 Aug; 166(5):1176-1187.e14. PubMed ID: 27545348
[TBL] [Abstract][Full Text] [Related]
14. Structural Basis Identified for Cholesterol Transport-Like Activity of the Hedgehog Receptor Patched: New evidence suggests that the Hedgehog receptor Patched may mediate cholesterol removal from the inner leaflet of the plasma membrane using a hydrophobic conduit.
Am J Med Genet A; 2019 Apr; 179(4):518-519. PubMed ID: 30864284
[No Abstract] [Full Text] [Related]
15. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
[TBL] [Abstract][Full Text] [Related]
16. GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum.
Qiu ZP; Lin ZC; Hu A; Liu YB; Zeng WE; Zhao X; Shi XJ; Luo J; Song BL
EMBO J; 2023 Feb; 42(3):e111513. PubMed ID: 36524353
[TBL] [Abstract][Full Text] [Related]
17. Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium.
Myers BR; Neahring L; Zhang Y; Roberts KJ; Beachy PA
Proc Natl Acad Sci U S A; 2017 Dec; 114(52):E11141-E11150. PubMed ID: 29229834
[TBL] [Abstract][Full Text] [Related]
18. Mechanistic Insights into the Generation and Transduction of Hedgehog Signaling.
Qi X; Li X
Trends Biochem Sci; 2020 May; 45(5):397-410. PubMed ID: 32311334
[TBL] [Abstract][Full Text] [Related]
19. Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol.
Weiss LE; Milenkovic L; Yoon J; Stearns T; Moerner WE
Proc Natl Acad Sci U S A; 2019 Mar; 116(12):5550-5557. PubMed ID: 30819883
[TBL] [Abstract][Full Text] [Related]
20. Biochemical mechanisms of vertebrate hedgehog signaling.
Kong JH; Siebold C; Rohatgi R
Development; 2019 May; 146(10):. PubMed ID: 31092502
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]