These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 31251599)

  • 1. Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1
    Wang Q; Arnst KE; Wang Y; Kumar G; Ma D; White SW; Miller DD; Li W; Li W
    J Med Chem; 2019 Jul; 62(14):6734-6750. PubMed ID: 31251599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy.
    Arnst KE; Wang Y; Lei ZN; Hwang DJ; Kumar G; Ma D; Parke DN; Chen Q; Yang J; White SW; Seagroves TN; Chen ZS; Miller DD; Li W
    Mol Pharmacol; 2019 Jul; 96(1):73-89. PubMed ID: 31043459
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
    Arnst KE; Wang Y; Hwang DJ; Xue Y; Costello T; Hamilton D; Chen Q; Yang J; Park F; Dalton JT; Miller DD; Li W
    Cancer Res; 2018 Jan; 78(1):265-277. PubMed ID: 29180476
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
    Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.
    Li CM; Lu Y; Chen J; Costello TA; Narayanan R; Dalton MN; Snyder LM; Ahn S; Li W; Miller DD; Dalton JT
    Pharm Res; 2012 Nov; 29(11):3053-63. PubMed ID: 22760659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R; Huang M; Zhang S; Li L; Li M; Sun J; Wu L; Guan Q; Zhang W
    Eur J Med Chem; 2021 Dec; 226():113826. PubMed ID: 34571171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site.
    Li L; Jiang S; Li X; Liu Y; Su J; Chen J
    Eur J Med Chem; 2018 May; 151():482-494. PubMed ID: 29649743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents.
    Chen J; Wang Z; Li CM; Lu Y; Vaddady PK; Meibohm B; Dalton JT; Miller DD; Li W
    J Med Chem; 2010 Oct; 53(20):7414-27. PubMed ID: 20919720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A; Rao MP; Das P; Swapna P; Polepalli S; Nimbarte VD; Mullagiri K; Kovvuri J; Jain N
    ChemMedChem; 2014 Jul; 9(7):1463-75. PubMed ID: 24715721
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New ligands of the tubulin colchicine site based on X-ray structures.
    Álvarez R; Medarde M; Peláez R
    Curr Top Med Chem; 2014; 14(20):2231-52. PubMed ID: 25434358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y; Yang J; Niu L; Hu D; Li H; Chen L; Yu Y; Chen Q
    FEBS Lett; 2020 Jan; 594(1):199-204. PubMed ID: 31369682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
    Cheng J; Wu Y; Wang Y; Wang C; Wang Y; Wu C; Zeng S; Yu Y; Chen Q
    Biochem Biophys Res Commun; 2018 Jan; 495(1):185-188. PubMed ID: 29102632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
    Romagnoli R; Prencipe F; Oliva P; Kimatrai Salvador M; Brancale A; Ferla S; Hamel E; Viola G; Bortolozzi R; Persoons L; Balzarini J; Liekens S; Schols D
    Bioorg Chem; 2020 Apr; 97():103665. PubMed ID: 32086053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
    Tian C; Chen X; Zhang Z; Wang X; Liu J
    Eur J Med Chem; 2019 Dec; 183():111679. PubMed ID: 31541870
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and Biological Evaluation of 1-Methyl-1H-indole-Pyrazoline Hybrids as Potential Tubulin Polymerization Inhibitors.
    Zhang YL; Qin YJ; Tang DJ; Yang MR; Li BY; Wang YT; Cai HY; Wang BZ; Zhu HL
    ChemMedChem; 2016 Jul; 11(13):1446-58. PubMed ID: 27159418
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent.
    Shetty RS; Lee Y; Liu B; Husain A; Joseph RW; Lu Y; Nelson D; Mihelcic J; Chao W; Moffett KK; Schumacher A; Flubacher D; Stojanovic A; Bukhtiyarova M; Williams K; Lee KJ; Ochman AR; Saporito MS; Moore WR; Flynn GA; Dorsey BD; Springman EB; Fujimoto T; Kelly MJ
    J Med Chem; 2011 Jan; 54(1):179-200. PubMed ID: 21126027
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
    Li W; Shuai W; Sun H; Xu F; Bi Y; Xu J; Ma C; Yao H; Zhu Z; Xu S
    Eur J Med Chem; 2019 Feb; 163():428-442. PubMed ID: 30530194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
    J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
    Kazan F; Yagci ZB; Bai R; Ozkirimli E; Hamel E; Ozkirimli S
    Comput Biol Chem; 2019 Jun; 80():512-523. PubMed ID: 31185422
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
    Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
    Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.