BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 31251990)

  • 1. Optimization of Population Frequency Cutoffs for Filtering Common Germline Polymorphisms from Tumor-Only Next-Generation Sequencing Data.
    McNulty SN; Parikh BA; Duncavage EJ; Heusel JW; Pfeifer JD
    J Mol Diagn; 2019 Sep; 21(5):903-912. PubMed ID: 31251990
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal.
    Sun JX; He Y; Sanford E; Montesion M; Frampton GM; Vignot S; Soria JC; Ross JS; Miller VA; Stephens PJ; Lipson D; Yelensky R
    PLoS Comput Biol; 2018 Feb; 14(2):e1005965. PubMed ID: 29415044
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A method to reduce ancestry related germline false positives in tumor only somatic variant calling.
    Halperin RF; Carpten JD; Manojlovic Z; Aldrich J; Keats J; Byron S; Liang WS; Russell M; Enriquez D; Claasen A; Cherni I; Awuah B; Oppong J; Wicha MS; Newman LA; Jaigge E; Kim S; Craig DW
    BMC Med Genomics; 2017 Oct; 10(1):61. PubMed ID: 29052513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants.
    Rasnic R; Brandes N; Zuk O; Linial M
    BMC Cancer; 2019 Aug; 19(1):783. PubMed ID: 31391007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy.
    Gray PN; Vuong H; Tsai P; Lu HM; Mu W; Hsuan V; Hoo J; Shah S; Uyeda L; Fox S; Patel H; Janicek M; Brown S; Dobrea L; Wagman L; Plimack E; Mehra R; Golemis EA; Bilusic M; Zibelman M; Elliott A
    Oncotarget; 2016 Oct; 7(42):68206-68228. PubMed ID: 27626691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition.
    Lau TTY; May CM; Sefid Dashti ZJ; Swanson L; Starks ER; Parker JDK; Moore RA; Tucker T; Bosdet I; Young SS; Santos JL; Compton K; Heidary N; Hoang L; Schrader KA; Sun S; Kwon JS; Tinker AV; Karsan A
    J Mol Diagn; 2021 Sep; 23(9):1145-1158. PubMed ID: 34197922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Detecting statistical interaction between somatic mutational events and germline variation from next-generation sequence data.
    Hu H; Huff CD
    Pac Symp Biocomput; 2014; ():51-62. PubMed ID: 24297533
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Annotation of Variant Data from High-Throughput DNA Sequencing from Tumor Specimens: Filtering Strategies to Identify Driver Mutations.
    Sun S; Thorson JA; Murray SS
    Methods Mol Biol; 2019; 1908():49-60. PubMed ID: 30649720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels.
    Sukhai MA; Misyura M; Thomas M; Garg S; Zhang T; Stickle N; Virtanen C; Bedard PL; Siu LL; Smets T; Thijs G; Van Vooren S; Kamel-Reid S; Stockley TL
    J Mol Diagn; 2019 Mar; 21(2):261-273. PubMed ID: 30576869
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Somatic mutation panels: Time to clear their names.
    Trottier AM; Cavalcante de Andrade Silva M; Li Z; Godley LA
    Cancer Genet; 2019 Jun; 235-236():84-92. PubMed ID: 31101556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Investigation of clinically relevant germline variants detected by next-generation sequencing in patients with childhood cancer: a review of the literature.
    Sylvester DE; Chen Y; Jamieson RV; Dalla-Pozza L; Byrne JA
    J Med Genet; 2018 Dec; 55(12):785-793. PubMed ID: 30287599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Germline contamination and leakage in whole genome somatic single nucleotide variant detection.
    Sendorek DH; Caloian C; Ellrott K; Bare JC; Yamaguchi TN; Ewing AD; Houlahan KE; Norman TC; Margolin AA; Stuart JM; Boutros PC
    BMC Bioinformatics; 2018 Jan; 19(1):28. PubMed ID: 29385983
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Accuracy and efficiency of germline variant calling pipelines for human genome data.
    Zhao S; Agafonov O; Azab A; Stokowy T; Hovig E
    Sci Rep; 2020 Nov; 10(1):20222. PubMed ID: 33214604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study.
    Casula M; Paliogiannis P; Ayala F; De Giorgi V; Stanganelli I; Mandalà M; Colombino M; Manca A; Sini MC; Caracò C; Ascierto PA; Satta RR; ; Lissia A; Cossu A; Palmieri G;
    BMC Cancer; 2019 Aug; 19(1):772. PubMed ID: 31382929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Origins and characterization of variants shared between databases of somatic and germline human mutations.
    Meyerson W; Leisman J; Navarro FCP; Gerstein M
    BMC Bioinformatics; 2020 Jun; 21(1):227. PubMed ID: 32498674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SNVSniffer: an integrated caller for germline and somatic single-nucleotide and indel mutations.
    Liu Y; Loewer M; Aluru S; Schmidt B
    BMC Syst Biol; 2016 Aug; 10 Suppl 2(Suppl 2):47. PubMed ID: 27489955
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumor Mutational Burden From Tumor-Only Sequencing Compared With Germline Subtraction From Paired Tumor and Normal Specimens.
    Parikh K; Huether R; White K; Hoskinson D; Beaubier N; Dong H; Adjei AA; Mansfield AS
    JAMA Netw Open; 2020 Feb; 3(2):e200202. PubMed ID: 32108894
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing.
    Cheng DT; Prasad M; Chekaluk Y; Benayed R; Sadowska J; Zehir A; Syed A; Wang YE; Somar J; Li Y; Yelskaya Z; Wong D; Robson ME; Offit K; Berger MF; Nafa K; Ladanyi M; Zhang L
    BMC Med Genomics; 2017 May; 10(1):33. PubMed ID: 28526081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluating somatic tumor mutation detection without matched normal samples.
    Teer JK; Zhang Y; Chen L; Welsh EA; Cress WD; Eschrich SA; Berglund AE
    Hum Genomics; 2017 Sep; 11(1):22. PubMed ID: 28870239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Open-Sourced CIViC Annotation Pipeline to Identify and Annotate Clinically Relevant Variants Using Single-Molecule Molecular Inversion Probes.
    Barnell EK; Waalkes A; Mosior MC; Penewit K; Cotto KC; Danos AM; Sheta LM; Campbell KM; Krysiak K; Rieke D; Spies NC; Skidmore ZL; Pritchard CC; Fehniger TA; Uppaluri R; Govindan R; Griffith M; Salipante SJ; Griffith OL
    JCO Clin Cancer Inform; 2019 Oct; 3():1-12. PubMed ID: 31618044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.