BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 31253706)

  • 1. Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
    Kopinski PK; Janssen KA; Schaefer PM; Trefely S; Perry CE; Potluri P; Tintos-Hernandez JA; Singh LN; Karch KR; Campbell SL; Doan MT; Jiang H; Nissim I; Nakamaru-Ogiso E; Wellen KE; Snyder NW; Garcia BA; Wallace DC
    Proc Natl Acad Sci U S A; 2019 Aug; 116(32):16028-16035. PubMed ID: 31253706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming.
    Picard M; Zhang J; Hancock S; Derbeneva O; Golhar R; Golik P; O'Hearn S; Levy S; Potluri P; Lvova M; Davila A; Lin CS; Perin JC; Rappaport EF; Hakonarson H; Trounce IA; Procaccio V; Wallace DC
    Proc Natl Acad Sci U S A; 2014 Sep; 111(38):E4033-42. PubMed ID: 25192935
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrial genomic integrity and the nuclear epigenome in health and disease.
    Morin AL; Win PW; Lin AZ; Castellani CA
    Front Endocrinol (Lausanne); 2022; 13():1059085. PubMed ID: 36419771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.
    Yang Q; Liu P; Anderson NS; Shpilka T; Du Y; Naresh NU; Li R; Zhu LJ; Luk K; Lavelle J; Zeinert RD; Chien P; Wolfe SA; Haynes CM
    Nat Cell Biol; 2022 Feb; 24(2):181-193. PubMed ID: 35165413
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bioenergetics and the epigenome: interface between the environment and genes in common diseases.
    Wallace DC
    Dev Disabil Res Rev; 2010; 16(2):114-9. PubMed ID: 20818725
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.
    Bulusu V; Tumanov S; Michalopoulou E; van den Broek NJ; MacKay G; Nixon C; Dhayade S; Schug ZT; Vande Voorde J; Blyth K; Gottlieb E; Vazquez A; Kamphorst JJ
    Cell Rep; 2017 Jan; 18(3):647-658. PubMed ID: 28099844
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Energetics, epigenetics, mitochondrial genetics.
    Wallace DC; Fan W
    Mitochondrion; 2010 Jan; 10(1):12-31. PubMed ID: 19796712
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs.
    Yang Y; Wu H; Kang X; Liang Y; Lan T; Li T; Tan T; Peng J; Zhang Q; An G; Liu Y; Yu Q; Ma Z; Lian Y; Soh BS; Chen Q; Liu P; Chen Y; Sun X; Li R; Zhen X; Liu P; Yu Y; Li X; Fan Y
    Protein Cell; 2018 Mar; 9(3):283-297. PubMed ID: 29318513
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression.
    Lozoya OA; Wang T; Grenet D; Wolfgang TC; Sobhany M; Ganini da Silva D; Riadi G; Chandel N; Woychik RP; Santos JH
    Life Sci Alliance; 2019 Feb; 2(1):. PubMed ID: 30737248
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heteroplasmy and Copy Number in the Common m.3243A>G Mutation-A Post-Mortem Genotype-Phenotype Analysis.
    Scholle LM; Zierz S; Mawrin C; Wickenhauser C; Urban DL
    Genes (Basel); 2020 Feb; 11(2):. PubMed ID: 32085658
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Assessment of Nuclear and Mitochondrial DNA, Expression of Mitochondria-Related Genes in Different Brain Regions in Rats after Whole-Body X-ray Irradiation.
    Abdullaev S; Gubina N; Bulanova T; Gaziev A
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32054039
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner.
    Loutre R; Heckel AM; Jeandard D; Tarassov I; Entelis N
    PLoS One; 2018; 13(6):e0199258. PubMed ID: 29912984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality.
    Tranah GJ; Katzman SM; Lauterjung K; Yaffe K; Manini TM; Kritchevsky S; Newman AB; Harris TB; Cummings SR
    Sci Rep; 2018 Aug; 8(1):11887. PubMed ID: 30089816
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear genetic control of mtDNA copy number and heteroplasmy in humans.
    Gupta R; Kanai M; Durham TJ; Tsuo K; McCoy JG; Kotrys AV; Zhou W; Chinnery PF; Karczewski KJ; Calvo SE; Neale BM; Mootha VK
    Nature; 2023 Aug; 620(7975):839-848. PubMed ID: 37587338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation.
    Sutendra G; Kinnaird A; Dromparis P; Paulin R; Stenson TH; Haromy A; Hashimoto K; Zhang N; Flaim E; Michelakis ED
    Cell; 2014 Jul; 158(1):84-97. PubMed ID: 24995980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determining Mitochondrial 3243A>G Heteroplasmy Using an ARMS-ddPCR Strategy.
    Xu P; Jia M; Yan J; Yuan X; Yu W; Zhou Z; Fang H; Gao F; Shen L
    Am J Clin Pathol; 2022 May; 157(5):664-677. PubMed ID: 34698344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The MELAS mutation m.3243A>G promotes reactivation of fetal cardiac genes and an epithelial-mesenchymal transition-like program via dysregulation of miRNAs.
    Meseguer S; Panadero J; Navarro-González C; Villarroya M; Boutoual R; Comi GP; Armengod ME
    Biochim Biophys Acta Mol Basis Dis; 2018 Sep; 1864(9 Pt B):3022-3037. PubMed ID: 29928977
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of chemically modified oligonucleotides targeting a pathogenic mutation in human mitochondrial DNA.
    Tonin Y; Heckel AM; Dovydenko I; Meschaninova M; Comte C; Venyaminova A; Pyshnyi D; Tarassov I; Entelis N
    Biochimie; 2014 May; 100():192-9. PubMed ID: 23994754
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.
    Takahashi H; McCaffery JM; Irizarry RA; Boeke JD
    Mol Cell; 2006 Jul; 23(2):207-17. PubMed ID: 16857587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutation analysis of the entire mitochondrial genome using denaturing high performance liquid chromatography.
    van Den Bosch BJ; de Coo RF; Scholte HR; Nijland JG; van Den Bogaard R; de Visser M; de Die-Smulders CE; Smeets HJ
    Nucleic Acids Res; 2000 Oct; 28(20):E89. PubMed ID: 11024191
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.