BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

427 related articles for article (PubMed ID: 31254394)

  • 1. α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities.
    Alam P; Bousset L; Melki R; Otzen DE
    J Neurochem; 2019 Sep; 150(5):522-534. PubMed ID: 31254394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research.
    Kumar ST; Donzelli S; Chiki A; Syed MMK; Lashuel HA
    J Neurochem; 2020 Apr; 153(1):103-119. PubMed ID: 31925956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the non-fibrillar α-synuclein oligomers.
    Hong DP; Han S; Fink AL; Uversky VN
    Protein Pept Lett; 2011 Mar; 18(3):230-40. PubMed ID: 20858207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies.
    Cascella R; Bigi A; Cremades N; Cecchi C
    Cell Mol Life Sci; 2022 Mar; 79(3):174. PubMed ID: 35244787
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Early stages of aggregation of engineered α-synuclein monomers and oligomers in solution.
    Li X; Dong C; Hoffmann M; Garen CR; Cortez LM; Petersen NO; Woodside MT
    Sci Rep; 2019 Feb; 9(1):1734. PubMed ID: 30741954
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells.
    Cascella R; Chen SW; Bigi A; Camino JD; Xu CK; Dobson CM; Chiti F; Cremades N; Cecchi C
    Nat Commun; 2021 Mar; 12(1):1814. PubMed ID: 33753734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insights into the Molecular Mechanisms of Alzheimer's and Parkinson's Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology.
    Coskuner-Weber O; Uversky VN
    Int J Mol Sci; 2018 Jan; 19(2):. PubMed ID: 29364151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.
    Uversky VN; Eliezer D
    Curr Protein Pept Sci; 2009 Oct; 10(5):483-99. PubMed ID: 19538146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. α-Synuclein aggregation at low concentrations.
    Afitska K; Fucikova A; Shvadchak VV; Yushchenko DA
    Biochim Biophys Acta Proteins Proteom; 2019; 1867(7-8):701-709. PubMed ID: 31096048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and functional properties of prefibrillar α-synuclein oligomers.
    Pieri L; Madiona K; Melki R
    Sci Rep; 2016 Apr; 6():24526. PubMed ID: 27075649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity.
    Carija A; Pinheiro F; Pujols J; Brás IC; Lázaro DF; Santambrogio C; Grandori R; Outeiro TF; Navarro S; Ventura S
    Redox Biol; 2019 Apr; 22():101135. PubMed ID: 30769283
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heme Stabilization of α-Synuclein Oligomers during Amyloid Fibril Formation.
    Hayden EY; Kaur P; Williams TL; Matsui H; Yeh SR; Rousseau DL
    Biochemistry; 2015 Aug; 54(30):4599-610. PubMed ID: 26161848
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pressure effects on α-synuclein amyloid fibrils: An experimental investigation on their dissociation and reversible nature.
    Piccirilli F; Plotegher N; Spinozzi F; Bubacco L; Mariani P; Beltramini M; Tessari I; Militello V; Perucchi A; Amenitsch H; Baldassarri E; Steinhart M; Lupi S; Ortore MG
    Arch Biochem Biophys; 2017 Aug; 627():46-55. PubMed ID: 28624352
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells.
    Pieri L; Madiona K; Bousset L; Melki R
    Biophys J; 2012 Jun; 102(12):2894-905. PubMed ID: 22735540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. α-Synuclein misfolding and aggregation: Implications in Parkinson's disease pathogenesis.
    Mehra S; Sahay S; Maji SK
    Biochim Biophys Acta Proteins Proteom; 2019 Oct; 1867(10):890-908. PubMed ID: 30853581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies.
    Bigi A; Cascella R; Cecchi C
    Neural Regen Res; 2023 Nov; 18(11):2332-2342. PubMed ID: 37282450
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural insights into amyloid oligomers of the Parkinson disease-related protein α-synuclein.
    Gallea JI; Celej MS
    J Biol Chem; 2014 Sep; 289(39):26733-26742. PubMed ID: 25143382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
    Conway KA; Harper JD; Lansbury PT
    Biochemistry; 2000 Mar; 39(10):2552-63. PubMed ID: 10704204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Small-Molecule-Induced Soluble Oligomers of α-Synuclein with Helical Structure.
    Fonseca-Ornelas L; Schmidt C; Camacho-Zarco AR; Fernandez CO; Becker S; Zweckstetter M
    Chemistry; 2017 Sep; 23(53):13010-13014. PubMed ID: 28763125
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic Amyloid Switch Triggered by Early Heterotypic Oligomerization of Intrinsically Disordered α-Synuclein and Tau.
    Bhasne K; Sebastian S; Jain N; Mukhopadhyay S
    J Mol Biol; 2018 Aug; 430(16):2508-2520. PubMed ID: 29704492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.