BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 31257073)

  • 1. RAC1
    Lionarons DA; Hancock DC; Rana S; East P; Moore C; Murillo MM; Carvalho J; Spencer-Dene B; Herbert E; Stamp G; Damry D; Calado DP; Rosewell I; Fritsch R; Neubig RR; Molina-Arcas M; Downward J
    Cancer Cell; 2019 Jul; 36(1):68-83.e9. PubMed ID: 31257073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF.
    Watson IR; Li L; Cabeceiras PK; Mahdavi M; Gutschner T; Genovese G; Wang G; Fang Z; Tepper JM; Stemke-Hale K; Tsai KY; Davies MA; Mills GB; Chin L
    Cancer Res; 2014 Sep; 74(17):4845-4852. PubMed ID: 25056119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting effector pathways in RAC1
    Uribe-Alvarez C; Guerrero-Rodríguez SL; Rhodes J; Cannon A; Chernoff J; Araiza-Olivera D
    Small GTPases; 2021 Jul; 12(4):273-281. PubMed ID: 32043900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.
    Mar VJ; Wong SQ; Logan A; Nguyen T; Cebon J; Kelly JW; Wolfe R; Dobrovic A; McLean C; McArthur GA
    Pigment Cell Melanoma Res; 2014 Nov; 27(6):1117-25. PubMed ID: 25043693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vemurafenib Drives Epithelial-to-Mesenchymal Transition Gene Expression in BRAF Inhibitor‒Resistant BRAF
    Jandova J; Wondrak GT
    J Invest Dermatol; 2022 May; 142(5):1456-1465.e1. PubMed ID: 34687745
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
    Cannon AC; Budagyan K; Uribe-Alvarez C; Kurimchak AM; Araiza-Olivera D; Cai KQ; Peri S; Zhou Y; Duncan JS; Chernoff J
    Oncogene; 2024 Mar; 43(10):729-743. PubMed ID: 38243078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAC1 P29S regulates PD-L1 expression in melanoma.
    Vu HL; Rosenbaum S; Purwin TJ; Davies MA; Aplin AE
    Pigment Cell Melanoma Res; 2015 Sep; 28(5):590-8. PubMed ID: 26176707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors.
    Araiza-Olivera D; Feng Y; Semenova G; Prudnikova TY; Rhodes J; Chernoff J
    Oncogene; 2018 Feb; 37(7):944-952. PubMed ID: 29059171
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
    Ramsdale R; Jorissen RN; Li FZ; Al-Obaidi S; Ward T; Sheppard KE; Bukczynska PE; Young RJ; Boyle SE; Shackleton M; Bollag G; Long GV; Tulchinsky E; Rizos H; Pearson RB; McArthur GA; Dhillon AS; Ferrao PT
    Sci Signal; 2015 Aug; 8(390):ra82. PubMed ID: 26286024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RAC1mutation is not a predictive biomarker for PI3'-kinase-β-selective pathway-targeted therapy.
    Foth M; Parkman G; Battistone B; McMahon M
    Pigment Cell Melanoma Res; 2020 Sep; 33(5):719-730. PubMed ID: 32406574
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RAC1 and melanoma.
    Halaban R
    Clin Ther; 2015 Mar; 37(3):682-5. PubMed ID: 25465943
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation.
    Byeon HK; Na HJ; Yang YJ; Ko S; Yoon SO; Ku M; Yang J; Kim JW; Ban MJ; Kim JH; Kim DH; Kim JM; Choi EC; Kim CH; Yoon JH; Koh YW
    Oncotarget; 2017 Jan; 8(1):596-609. PubMed ID: 27880942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1
    Mohan AS; Dean KM; Isogai T; Kasitinon SY; Murali VS; Roudot P; Groisman A; Reed DK; Welf ES; Han SJ; Noh J; Danuser G
    Dev Cell; 2019 May; 49(3):444-460.e9. PubMed ID: 31063759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic Differences of Activation of Rac1
    Senyuz S; Jang H; Nussinov R; Keskin O; Gursoy A
    J Phys Chem B; 2021 Apr; 125(15):3790-3802. PubMed ID: 33848152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterisation and outcome of RAC1 mutated melanoma.
    Lodde GC; Jansen P; Herbst R; Terheyden P; Utikal J; Pföhler C; Ulrich J; Kreuter A; Mohr P; Gutzmer R; Meier F; Dippel E; Weichenthal M; Sucker A; Placke JM; Zaremba A; Albrecht LJ; Kowall B; Galetzka W; Becker JC; Tasdogan A; Zimmer L; Livingstone E; Hadaschik E; Schadendorf D; Ugurel S; Griewank K
    Eur J Cancer; 2023 Apr; 183():1-10. PubMed ID: 36773463
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of point mutation P29S in RAC1 on tumorigenesis.
    Rajendran V; Gopalakrishnan C; Purohit R
    Tumour Biol; 2016 Nov; 37(11):15293-15304. PubMed ID: 27699663
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAC1P29S is a spontaneously activating cancer-associated GTPase.
    Davis MJ; Ha BH; Holman EC; Halaban R; Schlessinger J; Boggon TJ
    Proc Natl Acad Sci U S A; 2013 Jan; 110(3):912-7. PubMed ID: 23284172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma.
    Girard CA; Lecacheur M; Ben Jouira R; Berestjuk I; Diazzi S; Prod'homme V; Mallavialle A; Larbret F; Gesson M; Schaub S; Pisano S; Audebert S; Mari B; Gaggioli C; Leucci E; Marine JC; Deckert M; Tartare-Deckert S
    Cancer Res; 2020 May; 80(10):1927-1941. PubMed ID: 32179513
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells.
    Lin R; Xia S; Shan C; Chen D; Liu Y; Gao X; Wang M; Kang HB; Pan Y; Liu S; Chung YR; Abdel-Wahab O; Merghoub T; Rossi M; Kudchadkar RR; Lawson DH; Khuri FR; Lonial S; Chen J
    Mol Cell; 2018 Mar; 69(6):923-937.e8. PubMed ID: 29547721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1
    Tomino T; Tajiri H; Tatsuguchi T; Shirai T; Oisaki K; Matsunaga S; Sanematsu F; Sakata D; Yoshizumi T; Maehara Y; Kanai M; Cote JF; Fukui Y; Uruno T
    Biochem Biophys Res Commun; 2018 Feb; 497(1):298-304. PubMed ID: 29432733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.