BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 31257175)

  • 1. EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis.
    Lee SW; Zhang Y; Jung M; Cruz N; Alas B; Commisso C
    Dev Cell; 2019 Aug; 50(3):381-392.e5. PubMed ID: 31257175
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rac1 and EGFR cooperate to activate Pak in response to nutrient stress.
    Lee SW; Commisso C
    Biochem Biophys Res Commun; 2020 Dec; 533(3):437-441. PubMed ID: 32972756
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness.
    Zhang Y; Recouvreux MV; Jung M; Galenkamp KMO; Li Y; Zagnitko O; Scott DA; Lowy AM; Commisso C
    Cancer Discov; 2021 Jul; 11(7):1808-1825. PubMed ID: 33653692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
    Kamphorst JJ; Nofal M; Commisso C; Hackett SR; Lu W; Grabocka E; Vander Heiden MG; Miller G; Drebin JA; Bar-Sagi D; Thompson CB; Rabinowitz JD
    Cancer Res; 2015 Feb; 75(3):544-53. PubMed ID: 25644265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras.
    Lee SW; Commisso C
    Biochem Biophys Res Commun; 2020 Dec; 533(3):424-428. PubMed ID: 32972751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras.
    Sung S; Choi J; Cheong H
    Oncotarget; 2015 Dec; 6(38):40405-17. PubMed ID: 26575954
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
    Commisso C; Davidson SM; Soydaner-Azeloglu RG; Parker SJ; Kamphorst JJ; Hackett S; Grabocka E; Nofal M; Drebin JA; Thompson CB; Rabinowitz JD; Metallo CM; Vander Heiden MG; Bar-Sagi D
    Nature; 2013 May; 497(7451):633-7. PubMed ID: 23665962
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy is required for PDAC glutamine metabolism.
    Seo JW; Choi J; Lee SY; Sung S; Yoo HJ; Kang MJ; Cheong H; Son J
    Sci Rep; 2016 Nov; 6():37594. PubMed ID: 27892481
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition.
    Michalopoulou E; Auciello FR; Bulusu V; Strachan D; Campbell AD; Tait-Mulder J; Karim SA; Morton JP; Sansom OJ; Kamphorst JJ
    Cell Rep; 2020 Feb; 30(8):2729-2742.e4. PubMed ID: 32101748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors.
    Davidson SM; Jonas O; Keibler MA; Hou HW; Luengo A; Mayers JR; Wyckoff J; Del Rosario AM; Whitman M; Chin CR; Condon KJ; Lammers A; Kellersberger KA; Stall BK; Stephanopoulos G; Bar-Sagi D; Han J; Rabinowitz JD; Cima MJ; Langer R; Vander Heiden MG
    Nat Med; 2017 Feb; 23(2):235-241. PubMed ID: 28024083
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell polarity proteins promote macropinocytosis in response to metabolic stress.
    Lambies G; Lee SW; Duong-Polk K; Aza-Blanc P; Maganti S; Dawson DW; Commisso C
    bioRxiv; 2024 Jan; ():. PubMed ID: 38293142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SNAT7 regulates mTORC1 via macropinocytosis.
    Meng D; Yang Q; Jeong MH; Curukovic A; Tiwary S; Melick CH; Lama-Sherpa TD; Wang H; Huerta-Rosario M; Urquhart G; Zacharias LG; Lewis C; DeBerardinis RJ; Jewell JL
    Proc Natl Acad Sci U S A; 2022 May; 119(20):e2123261119. PubMed ID: 35561222
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EGFR Pathway Links Amino Acid Levels and Induction of Macropinocytosis.
    Weerasekara VK; Patra KC; Bardeesy N
    Dev Cell; 2019 Aug; 50(3):261-263. PubMed ID: 31386860
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis.
    Thu PM; Zheng ZG; Zhou YP; Wang YY; Zhang X; Jing D; Cheng HM; Li J; Li P; Xu X
    Eur J Pharmacol; 2019 May; 850():23-34. PubMed ID: 30716311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
    De Santis MC; Gozzelino L; Margaria JP; Costamagna A; Ratto E; Gulluni F; Di Gregorio E; Mina E; Lorito N; Bacci M; Lattanzio R; Sala G; Cappello P; Novelli F; Giovannetti E; Vicentini C; Andreani S; Delfino P; Corbo V; Scarpa A; Porporato PE; Morandi A; Hirsch E; Martini M
    Gut; 2023 Feb; 72(2):360-371. PubMed ID: 35623884
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma.
    Li W; Chen C; Zhao X; Ye H; Zhao Y; Fu Z; Pan W; Zheng S; Wei L; Nong T; Li Z; Chen R
    J Cell Mol Med; 2017 Nov; 21(11):2896-2908. PubMed ID: 28544376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer.
    Xiong X; Rao G; Roy RV; Zhang Y; Means N; Dey A; Tsaliki M; Saha S; Bhattacharyya S; Dhar Dwivedi SK; Rao CV; McCormick DJ; Dhanasekaran D; Ding K; Gillies E; Zhang M; Yang D; Bhattacharya R; Mukherjee P
    FASEB J; 2020 Sep; 34(9):12024-12039. PubMed ID: 32692445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice.
    Jiang SH; Li J; Dong FY; Yang JY; Liu DJ; Yang XM; Wang YH; Yang MW; Fu XL; Zhang XX; Li Q; Pang XF; Huo YM; Li J; Zhang JF; Lee HY; Lee SJ; Qin WX; Gu JR; Sun YW; Zhang ZG
    Gastroenterology; 2017 Jul; 153(1):277-291.e19. PubMed ID: 28315323
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis.
    Su H; Yang F; Fu R; Li X; French R; Mose E; Pu X; Trinh B; Kumar A; Liu J; Antonucci L; Todoric J; Liu Y; Hu Y; Diaz-Meco MT; Moscat J; Metallo CM; Lowy AM; Sun B; Karin M
    Cancer Cell; 2021 May; 39(5):678-693.e11. PubMed ID: 33740421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
    Nagathihalli NS; Castellanos JA; Lamichhane P; Messaggio F; Shi C; Dai X; Rai P; Chen X; VanSaun MN; Merchant NB
    Cancer Res; 2018 Nov; 78(21):6235-6246. PubMed ID: 30154150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.