BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 31257852)

  • 1. Novel Positive Allosteric Modulators of Glutamate Transport Have Neuroprotective Properties in an in Vitro Excitotoxic Model.
    Falcucci RM; Wertz R; Green JL; Meucci O; Salvino J; Fontana ACK
    ACS Chem Neurosci; 2019 Aug; 10(8):3437-3453. PubMed ID: 31257852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2.
    Kortagere S; Mortensen OV; Xia J; Lester W; Fang Y; Srikanth Y; Salvino JM; Fontana ACK
    ACS Chem Neurosci; 2018 Mar; 9(3):522-534. PubMed ID: 29140675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics.
    Kim K; Lee SG; Kegelman TP; Su ZZ; Das SK; Dash R; Dasgupta S; Barral PM; Hedvat M; Diaz P; Reed JC; Stebbins JL; Pellecchia M; Sarkar D; Fisher PB
    J Cell Physiol; 2011 Oct; 226(10):2484-93. PubMed ID: 21792905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Current approaches to enhance glutamate transporter function and expression.
    Fontana AC
    J Neurochem; 2015 Sep; 134(6):982-1007. PubMed ID: 26096891
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.
    van Veggel L; Mocking TAM; Sijben HJ; Liu R; Gorostiola González M; Dilweg MA; Royakkers J; Li A; Kumar V; Dong YY; Bullock A; Sauer DB; Diliën H; van Westen GJP; Schreiber R; Heitman LH; Vanmierlo T
    ACS Chem Neurosci; 2024 Apr; 15(7):1424-1431. PubMed ID: 38478848
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.
    Colton CK; Kong Q; Lai L; Zhu MX; Seyb KI; Cuny GD; Xian J; Glicksman MA; Lin CL
    J Biomol Screen; 2010 Jul; 15(6):653-62. PubMed ID: 20508255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: Opportunities for novel therapeutics development.
    Green JL; Dos Santos WF; Fontana ACK
    Biochem Pharmacol; 2021 Nov; 193():114786. PubMed ID: 34571003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.
    Kong Q; Chang LC; Takahashi K; Liu Q; Schulte DA; Lai L; Ibabao B; Lin Y; Stouffer N; Das Mukhopadhyay C; Xing X; Seyb KI; Cuny GD; Glicksman MA; Lin CL
    J Clin Invest; 2014 Mar; 124(3):1255-67. PubMed ID: 24569372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes.
    Lee SG; Su ZZ; Emdad L; Gupta P; Sarkar D; Borjabad A; Volsky DJ; Fisher PB
    J Biol Chem; 2008 May; 283(19):13116-23. PubMed ID: 18326497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular determinants of transport stimulation of EAAT2 are located at interface between the trimerization and substrate transport domains.
    Mortensen OV; Liberato JL; Coutinho-Netto J; Dos Santos WF; Fontana AC
    J Neurochem; 2015 Apr; 133(2):199-210. PubMed ID: 25626691
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuroprotective Effects of the Glutamate Transporter Activator (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153) following Traumatic Brain Injury in the Adult Rat.
    Fontana AC; Fox DP; Zoubroulis A; Mortensen OV; Raghupathi R
    J Neurotrauma; 2016 Jun; 33(11):1073-83. PubMed ID: 26200170
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection.
    Romera C; Hurtado O; Mallolas J; Pereira MP; Morales JR; Romera A; Serena J; Vivancos J; Nombela F; Lorenzo P; Lizasoain I; Moro MA
    J Cereb Blood Flow Metab; 2007 Jul; 27(7):1327-38. PubMed ID: 17213861
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.
    Hurtado O; Pradillo JM; Fernández-López D; Morales JR; Sobrino T; Castillo J; Alborch E; Moro MA; Lizasoain I
    Neurobiol Dis; 2008 Jan; 29(1):123-31. PubMed ID: 17884513
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Over-expression of the human EAAT2 glutamate transporter within neurons of mouse organotypic hippocampal slice cultures leads to increased vulnerability of CA1 pyramidal cells.
    Selkirk JV; Stiefel TH; Stone IM; Naeve GS; Foster AC; Poulsen DJ
    Eur J Neurosci; 2005 Apr; 21(8):2291-6. PubMed ID: 15869527
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Translational enhancers of EAAT2: therapeutic implications for neurodegenerative disease.
    Limpert AS; Cosford ND
    J Clin Invest; 2014 Mar; 124(3):964-7. PubMed ID: 24569369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targets of cytoprotection in acute ischemic stroke: present and future.
    Lizasoain I; Cárdenas A; Hurtado O; Romera C; Mallolas J; Lorenzo P; Castillo J; Moro MA
    Cerebrovasc Dis; 2006; 21 Suppl 2():1-8. PubMed ID: 16651809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport.
    Hurtado O; Moro MA; Cárdenas A; Sánchez V; Fernández-Tomé P; Leza JC; Lorenzo P; Secades JJ; Lozano R; Dávalos A; Castillo J; Lizasoain I
    Neurobiol Dis; 2005 Mar; 18(2):336-45. PubMed ID: 15686962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
    Zhou X; Liang J; Wang J; Fei Z; Qin G; Zhang D; Zhou J; Chen L
    J Neurochem; 2020 Nov; 155(4):370-389. PubMed ID: 31872442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tinospora cordifolia as a potential neuroregenerative candidate against glutamate induced excitotoxicity: an in vitro perspective.
    Sharma A; Kaur G
    BMC Complement Altern Med; 2018 Oct; 18(1):268. PubMed ID: 30285727
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Positive allosteric activation of glial EAAT-2 transporter protein: A novel strategy for Alzheimer's disease.
    Manisha C; Selvaraj A; Jubie S; Moola Joghee Nanjan C; Moola Joghee N; Clement JP; Justin A
    Med Hypotheses; 2020 Sep; 142():109794. PubMed ID: 32413698
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.