BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 3126183)

  • 1. Structure-function analysis with tissue-type plasminogen activator. Effect of deletion of NH2-terminal domains on its biochemical and biological properties.
    Kalyan NK; Lee SG; Wilhelm J; Fu KP; Hum WT; Rappaport R; Hartzell RW; Urbano C; Hung PP
    J Biol Chem; 1988 Mar; 263(8):3971-8. PubMed ID: 3126183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Variants of human tissue-type plasminogen activator. Fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains.
    Larsen GR; Henson K; Blue Y
    J Biol Chem; 1988 Jan; 263(2):1023-9. PubMed ID: 3121618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of a recombinant fusion protein of the finger domain of tissue-type plasminogen activator with a truncated single chain urokinase-type plasminogen activator.
    Gheysen D; Lijnen HR; Piérard L; de Foresta F; Demarsin E; Jacobs P; De Wilde M; Bollen A; Collen D
    J Biol Chem; 1987 Aug; 262(24):11779-84. PubMed ID: 3114253
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of a modified human tissue plasminogen activator comprising a kringle-2 and a protease domain.
    Burck PJ; Berg DH; Warrick MW; Berg DT; Walls JD; Jaskunas SR; Crisel RM; Weigel B; Vlahos CJ; McClure DB
    J Biol Chem; 1990 Mar; 265(9):5170-7. PubMed ID: 2108167
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Construction and expression of hybrid plasminogen activators prepared from tissue-type plasminogen activator and urokinase-type plasminogen activator genes.
    Lee SG; Kalyan N; Wilhelm J; Hum WT; Rappaport R; Cheng SM; Dheer S; Urbano C; Hartzell RW; Ronchetti-Blume M
    J Biol Chem; 1988 Feb; 263(6):2917-24. PubMed ID: 3125172
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Replacement of finger and growth factor domains of tissue plasminogen activator with plasminogen kringle 1. Biochemical and pharmacological characterization of a novel chimera containing a high affinity fibrin-binding domain linked to a heterologous protein.
    Langer-Safer PR; Ahern TJ; Angus LB; Barone KM; Brenner MJ; Horgan PG; Morris GE; Stoudemire JB; Timony GA; Larsen GR
    J Biol Chem; 1991 Feb; 266(6):3715-23. PubMed ID: 1847387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator.
    Bakker AH; Nieuwenbroek NM; Verheijen JH
    Protein Eng; 1995 Dec; 8(12):1295-1302. PubMed ID: 8869642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and function of human tissue-type plasminogen activator (t-PA).
    van Zonneveld AJ; Veerman H; MacDonald ME; van Mourik JA; Pannekoek H
    J Cell Biochem; 1986; 32(3):169-78. PubMed ID: 3097031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fibrin affinity and clearance of t-PA deletion and substitution analogues.
    Johannessen M; Diness V; Pingel K; Petersen LC; Rao D; Lioubin P; O'Hara P; Mulvihill E
    Thromb Haemost; 1990 Feb; 63(1):54-9. PubMed ID: 2111048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autonomous functions of structural domains on human tissue-type plasminogen activator.
    van Zonneveld AJ; Veerman H; Pannekoek H
    Proc Natl Acad Sci U S A; 1986 Jul; 83(13):4670-4. PubMed ID: 3088564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a chimeric plasminogen activator consisting of amino acids 1 to 274 of tissue-type plasminogen activator and amino acids 138 to 411 of single-chain urokinase-type plasminogen activator.
    Lijnen HR; Nelles L; Van Hoef B; Demarsin E; Collen D
    J Biol Chem; 1988 Dec; 263(35):19083-91. PubMed ID: 3143723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tissue-type plasminogen activator and its substrate Glu-plasminogen share common binding sites in limited plasmin-digested fibrin.
    de Vries C; Veerman H; Koornneef E; Pannekoek H
    J Biol Chem; 1990 Aug; 265(23):13547-52. PubMed ID: 2143185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator.
    Nelles L; Lijnen HR; Collen D; Holmes WE
    J Biol Chem; 1987 Aug; 262(22):10855-62. PubMed ID: 2956260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A covalent molecular weight approximately 92,000 hybrid plasminogen activator derived from human plasmin fibrin-binding and tissue plasminogen activator catalytic domains.
    Robbins KC; Boreisha IG
    Biochemistry; 1987 Jul; 26(15):4661-7. PubMed ID: 3117104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical and functional characterization of human tissue-type plasminogen activator variants obtained by deletion and/or duplication of structural/functional domains.
    Lijnen HR; Nelles L; Van Hoef B; De Cock F; Collen D
    J Biol Chem; 1990 Apr; 265(10):5677-83. PubMed ID: 2156824
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Artificial exon shuffling between tissue-type plasminogen activator (t-PA) and urokinase (u-PA): a comparative study on the fibrinolytic properties of t-PA/u-PA hybrid proteins.
    de Vries C; Veerman H; Blasi F; Pannekoek H
    Biochemistry; 1988 Apr; 27(7):2565-72. PubMed ID: 3132969
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The position of the structurally autonomous kringle 2 domain influences the functional features of tissue-type plasminogen activator.
    Bakker AH; Rehberg EF; Marotti KR; Verheijen JH
    Protein Eng; 1995 Mar; 8(3):293-300. PubMed ID: 7479691
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic characterization of tissue-type plasminogen activator (t-PA) and t-PA deletion mutants.
    de Vries C; Veerman H; Nesheim ME; Pannekoek H
    Thromb Haemost; 1991 Mar; 65(3):280-5. PubMed ID: 1904654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deglycosylation increases the fibrinolytic activity of a deletion mutant of tissue-type plasminogen activator.
    Wilhelm J; Kalyan NK; Lee SG; Hum WT; Rappaport R; Hung PP
    Thromb Haemost; 1990 Jun; 63(3):464-71. PubMed ID: 2119528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a chimaeric plasminogen activator obtained by insertion of the second kringle structure of tissue-type plasminogen activator (amino acids 173 through 262) between residues Asp130 and Ser139 of urokinase-type plasminogen activator.
    Lijnen HR; Piérard L; Reff ME; Gheysen D
    Thromb Res; 1988 Dec; 52(5):431-41. PubMed ID: 3146822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.