233 related articles for article (PubMed ID: 3126255)
1. Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
Bacha P; Williams DP; Waters C; Williams JM; Murphy JR; Strom TB
J Exp Med; 1988 Feb; 167(2):612-22. PubMed ID: 3126255
[TBL] [Abstract][Full Text] [Related]
2. Interleukin 2 receptor-targeted cytotoxicity. Receptor binding requirements for entry of a diphtheria toxin-related interleukin 2 fusion protein into cells.
Waters CA; Schimke PA; Snider CE; Itoh K; Smith KA; Nichols JC; Strom TB; Murphy JR
Eur J Immunol; 1990 Apr; 20(4):785-91. PubMed ID: 2140788
[TBL] [Abstract][Full Text] [Related]
3. Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related murine interleukin 4 fusion protein.
Lakkis F; Steele A; Pacheco-Silva A; Rubin-Kelley V; Strom TB; Murphy JR
Eur J Immunol; 1991 Sep; 21(9):2253-8. PubMed ID: 1679715
[TBL] [Abstract][Full Text] [Related]
4. PHA induces IL-2 receptors on B-CLL cells and is a potential biological response modifier for the LIL-2-diphtheria toxin, DAB486IL-2.
Bulger K; Padua F; Duff R; Pihan G; Nichols J; Murphy J; McCaffrey R
Leuk Res; 1994 Feb; 18(2):119-22. PubMed ID: 8107488
[TBL] [Abstract][Full Text] [Related]
5. Interleukin 2 toxin: a step toward selective immunomodulation.
Murphy JR; Kelley VE; Strom TB
Am J Kidney Dis; 1988 Feb; 11(2):159-62. PubMed ID: 3124610
[TBL] [Abstract][Full Text] [Related]
6. Cytotoxicity of interleukin 2-toxin toward lymphocytes from patients with adult T-cell leukemia.
Kiyokawa T; Shirono K; Hattori T; Nishimura H; Yamaguchi K; Nichols JC; Strom TB; Murphy JR; Takatsuki K
Cancer Res; 1989 Jul; 49(14):4042-6. PubMed ID: 2786749
[TBL] [Abstract][Full Text] [Related]
7. Diphtheria toxin receptor-binding domain substitution with interleukin 6: genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein.
Jean LF; Murphy JR
Protein Eng; 1991 Dec; 4(8):989-94. PubMed ID: 1817263
[TBL] [Abstract][Full Text] [Related]
8. Sequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activation.
Walz G; Zanker B; Brand K; Waters C; Genbauffe F; Zeldis JB; Murphy JR; Strom TB
Proc Natl Acad Sci U S A; 1989 Dec; 86(23):9485-8. PubMed ID: 2594781
[TBL] [Abstract][Full Text] [Related]
9. Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells.
Williams DP; Snider CE; Strom TB; Murphy JR
J Biol Chem; 1990 Jul; 265(20):11885-9. PubMed ID: 2195027
[TBL] [Abstract][Full Text] [Related]
10. Cell receptor specific targeted toxins: genetic construction and characterization of an interleukin 2 diphtheria toxin-related fusion protein.
Murphy JR; Williams DP; Bacha P; Bishai W; Waters C; Strom TB
J Recept Res; 1988; 8(1-4):467-80. PubMed ID: 3133472
[TBL] [Abstract][Full Text] [Related]
11. Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: a novel agent for the elimination of IL-7 receptor positive cells.
Sweeney EB; Foss FM; Murphy JR; vanderSpek JC
Bioconjug Chem; 1998; 9(2):201-7. PubMed ID: 9548535
[TBL] [Abstract][Full Text] [Related]
12. Protein engineering of diphtheria-toxin-related interleukin-2 fusion toxins to increase cytotoxic potency for high-affinity IL-2-receptor-bearing target cells.
Kiyokawa T; Williams DP; Snider CE; Strom TB; Murphy JR
Protein Eng; 1991 Apr; 4(4):463-8. PubMed ID: 1881872
[TBL] [Abstract][Full Text] [Related]
13. A kinetic analysis of the effects of interleukin-2 diphtheria toxin fusion protein upon activated T cells.
Walz G; Zanker B; Murphy JR; Strom TB
Transplantation; 1990 Jan; 49(1):198-201. PubMed ID: 2301012
[TBL] [Abstract][Full Text] [Related]
14. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology.
Foss FM
Clin Lymphoma; 2000 Nov; 1 Suppl 1():S27-31. PubMed ID: 11707860
[TBL] [Abstract][Full Text] [Related]
15. Differential sensitivity of human myeloma cell lines and normal bone marrow colony forming cells to a recombinant diphtheria toxin-interleukin 6 fusion protein.
Chadwick DE; Jean LF; Jamal N; Messner HA; Murphy JR; Minden MD
Br J Haematol; 1993 Sep; 85(1):25-36. PubMed ID: 8251407
[TBL] [Abstract][Full Text] [Related]
16. Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.
Kelley VE; Bacha P; Pankewycz O; Nichols JC; Murphy JR; Strom TB
Proc Natl Acad Sci U S A; 1988 Jun; 85(11):3980-4. PubMed ID: 3131768
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of human antigen-specific memory B cell response in vitro by a diphtheria toxin-related interleukin 2 fusion protein.
Grailer AP; Nichols JC; Strom TB; Sollinger HW; Burlingham WJ
Cell Immunol; 1991 Feb; 132(2):481-93. PubMed ID: 1988163
[TBL] [Abstract][Full Text] [Related]
18. Peripheral blood hairy cell leukemia cells express only low affinity IL-2 receptors.
Bulger K; Murphy J; Janckila A; Nichols J; McCaffrey R
Leuk Res; 1994 Feb; 18(2):101-4. PubMed ID: 8107487
[TBL] [Abstract][Full Text] [Related]
19. Interleukin-2 fusion protein (DAB389IL-2) selectively targets activated human peripheral blood and lamina propria lymphocytes.
Bousvaros A; Stevens AC; Strom TB; Murphy J; Lamont JT
Dig Dis Sci; 1997 Jul; 42(7):1542-8. PubMed ID: 9246061
[TBL] [Abstract][Full Text] [Related]
20. Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
vanderSpek JC; Mindell JA; Finkelstein A; Murphy JR
J Biol Chem; 1993 Jun; 268(16):12077-82. PubMed ID: 8505330
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]