186 related articles for article (PubMed ID: 31268738)
1. Inhibition of CFTR-mediated intestinal chloride secretion as potential therapy for bile acid diarrhea.
Duan T; Cil O; Tse CM; Sarker R; Lin R; Donowitz M; Verkman AS
FASEB J; 2019 Oct; 33(10):10924-10934. PubMed ID: 31268738
[TBL] [Abstract][Full Text] [Related]
2. Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins.
Cil O; Phuan PW; Gillespie AM; Lee S; Tradtrantip L; Yin J; Tse M; Zachos NC; Lin R; Donowitz M; Verkman AS
FASEB J; 2017 Feb; 31(2):751-760. PubMed ID: 27871064
[TBL] [Abstract][Full Text] [Related]
3. Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea.
Duan T; Cil O; Thiagarajah JR; Verkman AS
JCI Insight; 2019 Feb; 4(4):. PubMed ID: 30668547
[TBL] [Abstract][Full Text] [Related]
4. Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells.
Ao M; Sarathy J; Domingue J; Alrefai WA; Rao MC
Am J Physiol Cell Physiol; 2013 Aug; 305(4):C447-56. PubMed ID: 23761628
[TBL] [Abstract][Full Text] [Related]
5. Chenodeoxycholic acid requires activation of EGFR, EPAC, and Ca2+ to stimulate CFTR-dependent Cl- secretion in human colonic T84 cells.
Domingue JC; Ao M; Sarathy J; Rao MC
Am J Physiol Cell Physiol; 2016 Nov; 311(5):C777-C792. PubMed ID: 27558159
[TBL] [Abstract][Full Text] [Related]
6. Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP.
Kim Y; Anderson MO; Park J; Lee MG; Namkung W; Verkman AS
Mol Pharmacol; 2015 Oct; 88(4):689-96. PubMed ID: 26174774
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a novel chalcone derivative inhibiting CFTR chloride channel via AMPK activation and its anti-diarrheal application.
Yibcharoenporn C; Chusuth P; Jakakul C; Rungrotmongkol T; Chavasiri W; Muanprasat C
J Pharmacol Sci; 2019 Jul; 140(3):273-283. PubMed ID: 31444000
[TBL] [Abstract][Full Text] [Related]
8. Lithocholic acid attenuates cAMP-dependent Cl- secretion in human colonic epithelial T84 cells.
Ao M; Domingue JC; Khan N; Javed F; Osmani K; Sarathy J; Rao MC
Am J Physiol Cell Physiol; 2016 Jun; 310(11):C1010-23. PubMed ID: 27076617
[TBL] [Abstract][Full Text] [Related]
9. Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas.
Oak AA; Chhetri PD; Rivera AA; Verkman AS; Cil O
JCI Insight; 2021 Feb; 6(4):. PubMed ID: 33400691
[TBL] [Abstract][Full Text] [Related]
10. Activation of constitutive androstane receptor inhibits intestinal CFTR-mediated chloride transport.
Kittayaruksakul S; Sawasvirojwong S; Noitem R; Pongkorpsakol P; Muanprasat C; Chatsudthipong V
Biomed Pharmacother; 2019 Mar; 111():1249-1259. PubMed ID: 30841439
[TBL] [Abstract][Full Text] [Related]
11. Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.
Snyder DS; Tradtrantip L; Yao C; Kurth MJ; Verkman AS
J Med Chem; 2011 Aug; 54(15):5468-77. PubMed ID: 21707078
[TBL] [Abstract][Full Text] [Related]
12. A plant-derived hydrolysable tannin inhibits CFTR chloride channel: a potential treatment of diarrhea.
Wongsamitkul N; Sirianant L; Muanprasat C; Chatsudthipong V
Pharm Res; 2010 Mar; 27(3):490-7. PubMed ID: 20225391
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of CFTR-mediated intestinal chloride secretion by a fungus-derived arthropsolide A: Mechanism of action and anti-diarrheal efficacy.
Akrimajirachoote N; Satitsri S; Sommart U; Rukachaisirikul V; Muanprasat C
Eur J Pharmacol; 2020 Oct; 885():173393. PubMed ID: 32712094
[TBL] [Abstract][Full Text] [Related]
14. CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis.
Verkman AS; Lukacs GL; Galietta LJ
Curr Pharm Des; 2006; 12(18):2235-47. PubMed ID: 16787252
[TBL] [Abstract][Full Text] [Related]
15. CFTR pharmacology and its role in intestinal fluid secretion.
Thiagarajah JR; Verkman AS
Curr Opin Pharmacol; 2003 Dec; 3(6):594-9. PubMed ID: 14644010
[TBL] [Abstract][Full Text] [Related]
16. Acute inflammation alters bicarbonate transport in mouse ileum.
Zhang H; Ameen N; Melvin JE; Vidyasagar S
J Physiol; 2007 Jun; 581(Pt 3):1221-33. PubMed ID: 17395634
[TBL] [Abstract][Full Text] [Related]
17. CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives.
Yang H; Xu LN; He CY; Liu X; Fang RY; Ma TH
Acta Pharmacol Sin; 2011 Jun; 32(6):834-9. PubMed ID: 21602836
[TBL] [Abstract][Full Text] [Related]
18. Cyclic AMP-induced K+ secretion occurs independently of Cl- secretion in rat distal colon.
Sandle GI; Rajendran VM
Am J Physiol Cell Physiol; 2012 Aug; 303(3):C328-33. PubMed ID: 22648950
[TBL] [Abstract][Full Text] [Related]
19. A fungal metabolite zearalenone as a CFTR inhibitor and potential therapy of secretory diarrheas.
Muangnil P; Satitsri S; Tadpetch K; Saparpakorn P; Chatsudthipong V; Hannongbua S; Rukachaisirikul V; Muanprasat C
Biochem Pharmacol; 2018 Apr; 150():293-304. PubMed ID: 29475061
[TBL] [Abstract][Full Text] [Related]
20. Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease.
Muanprasat C; Sirianant L; Soodvilai S; Chokchaisiri R; Suksamrarn A; Chatsudthipong V
J Pharmacol Sci; 2012; 118(1):82-91. PubMed ID: 22186622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]