BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 31271942)

  • 21. Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.
    Hebda M; Bajda M; Więckowska A; Szałaj N; Pasieka A; Panek D; Godyń J; Wichur T; Knez D; Gobec S; Malawska B
    Molecules; 2016 Mar; 21(4):410. PubMed ID: 27023510
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Chromone derivatives bearing pyridinium moiety as multi-target-directed ligands against Alzheimer's disease.
    Abdpour S; Jalili-Baleh L; Nadri H; Forootanfar H; Bukhari SNA; Ramazani A; Ebrahimi SES; Foroumadi A; Khoobi M
    Bioorg Chem; 2021 May; 110():104750. PubMed ID: 33691251
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
    Bai P; Wang K; Zhang P; Shi J; Cheng X; Zhang Q; Zheng C; Cheng Y; Yang J; Lu X; Sang Z
    Eur J Med Chem; 2019 Dec; 183():111737. PubMed ID: 31581002
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease.
    Bajad NG; Singh RB; T A G; Gutti G; Kumar A; Krishnamurthy S; Singh SK
    Bioorg Chem; 2024 Feb; 143():107082. PubMed ID: 38199142
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Non-Imidazole Histamine H₃ Ligands. Part VII. Synthesis, In Vitro and In Vivo Characterization of 5-Substituted-2-thiazol-4-n-propylpiperazines.
    Guryn R; Staszewski M; Stasiak A; McNaught Flores D; Fogel WA; Leurs R; Walczyński K
    Molecules; 2018 Feb; 23(2):. PubMed ID: 29401659
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT
    Więckowska A; Kołaczkowski M; Bucki A; Godyń J; Marcinkowska M; Więckowski K; Zaręba P; Siwek A; Kazek G; Głuch-Lutwin M; Mierzejewski P; Bienkowski P; Sienkiewicz-Jarosz H; Knez D; Wichur T; Gobec S; Malawska B
    Eur J Med Chem; 2016 Nov; 124():63-81. PubMed ID: 27560283
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB; Palaka BK; Penumala M; Kotapati KV; Devineni SR; Eadlapalli S; Darla MM; Ampasala DR; Vadde R; Amooru GD
    Eur J Med Chem; 2016 Jan; 107():219-32. PubMed ID: 26588065
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Optimization and preclinical evaluation of novel histamine H
    Szczepańska K; Karcz T; Kotańska M; Siwek A; Kuder KJ; Latacz G; Mogilski S; Hagenow S; Lubelska A; Sobolewski M; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem; 2018 Dec; 26(23-24):6056-6066. PubMed ID: 30448256
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of novel isoflavone derivatives as AChE/BuChE dual-targeted inhibitors: synthesis, biological evaluation and molecular modelling.
    Feng B; Li X; Xia J; Wu S
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):968-977. PubMed ID: 28718678
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Design, synthesis and biological evaluation of bakuchiol derivatives as multi-target agents for the treatment of Alzheimer's disease.
    Zhang XQ; Xiang YN; Qin T; Zou JP; Guo QW; Han ST; Zhang ZY; Liu WW; Ding G; Dong JQ; Shi DH
    Fitoterapia; 2024 Apr; 174():105867. PubMed ID: 38382891
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Non-imidazole histamine H
    Guryn R; Staszewski M; Walczyński K
    Med Chem Res; 2013 Aug; 22(8):3640-3652. PubMed ID: 23807824
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats.
    Sadek B; Khan N; Darras FH; Pockes S; Decker M
    Physiol Behav; 2016 Oct; 165():383-91. PubMed ID: 27568232
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H
    Michalska B; Dzięgielewski M; Godyń J; Werner T; Bajda M; Karcz T; Szczepańska K; Stark H; Więckowska A; Walczyński K; Staszewski M
    ACS Chem Neurosci; 2024 Mar; 15(6):1206-1218. PubMed ID: 38440987
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease.
    Hafez DE; Dubiel M; La Spada G; Catto M; Reiner-Link D; Syu YT; Abdel-Halim M; Hwang TL; Stark H; Abadi AH
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2175821. PubMed ID: 36789662
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution.
    Chen PY; Tsai CT; Ou CY; Hsu WT; Jhuo MD; Wu CH; Shih TC; Cheng TH; Chung JG
    Mol Med Rep; 2012 Apr; 5(4):1043-8. PubMed ID: 22267207
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and evaluation of substituted 4-methyl-2-oxo-2H-chromen-7-yl phenyl carbamates as potent acetylcholinesterase inhibitors and anti- amnestic agents.
    Anand P; Singh B
    Med Chem; 2013 Aug; 9(5):694-702. PubMed ID: 23072555
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
    Khan N; Saad A; Nurulain SM; Darras FH; Decker M; Sadek B
    Behav Brain Res; 2016 Jan; 297():155-64. PubMed ID: 26467607
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of Novel Pyrazolopyrimidinone Derivatives as Phosphodiesterase 9A Inhibitors Capable of Inhibiting Butyrylcholinesterase for Treatment of Alzheimer's Disease.
    Yu YF; Huang YD; Zhang C; Wu XN; Zhou Q; Wu D; Wu Y; Luo HB
    ACS Chem Neurosci; 2017 Nov; 8(11):2522-2534. PubMed ID: 28783948
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.