BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 31273226)

  • 1. A repository of protein abundance data of drug metabolizing enzymes and transporters for applications in physiologically based pharmacokinetic (PBPK) modelling and simulation.
    Ladumor MK; Thakur A; Sharma S; Rachapally A; Mishra S; Bobe P; Rao VK; Pammi P; Kangne H; Levi D; Balhara A; Ghandikota S; Joshi A; Nautiyal V; Prasad B; Singh S
    Sci Rep; 2019 Jul; 9(1):9709. PubMed ID: 31273226
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potential implications of DMET ontogeny on the disposition of commonly prescribed drugs in neonatal and pediatric intensive care units.
    Naji-Talakar S; Sharma S; Martin LA; Barnhart D; Prasad B
    Expert Opin Drug Metab Toxicol; 2021 Mar; 17(3):273-289. PubMed ID: 33256492
    [No Abstract]   [Full Text] [Related]  

  • 3.
    Singh DK; Ahire D; Davydov DR; Prasad B
    Drug Metab Dispos; 2024 Apr; ():. PubMed ID: 38641346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.
    Patilea-Vrana G; Unadkat JD
    Clin Pharmacol Ther; 2016 Nov; 100(5):413-418. PubMed ID: 27448198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assessment of the Utility of Physiologically-based Pharmacokinetic Model for prediction of Pharmacokinetics in Chinese and Japanese Populations.
    Yu Y; Lin J; Muto C; Li Y; Mori Y; Mittapalli RK; Tse S; Liu J; Ge BK; Liu J
    Int J Med Sci; 2021; 18(16):3718-3727. PubMed ID: 34790045
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Innovations, Opportunities, and Challenges for Predicting Alteration in Drug-Metabolizing Enzyme and Transporter Activity in Specific Populations.
    Chothe PP; Arya V; Prasad B; Ramsden D; Taskar K
    Drug Metab Dispos; 2023 Dec; 51(12):1547-1550. PubMed ID: 37775331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Physiologically Based Pharmacokinetic Model for Older Adults and Its Application in Geriatric Drug Research.
    Wu X; Sia JEV; Hai M; Lai X; Li H; Cui C; Liu D
    Curr Drug Metab; 2023; 24(3):211-222. PubMed ID: 37165496
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physiologically based pharmacokinetic modelling of semaglutide in children and adolescents with healthy and obese body weights.
    Machado TR; Honorio T; Souza Domingos TF; Candido de Paula DDS; Cabral LM; Rodrigues CR; Abrahim-Vieira BA; Teles de Souza AM
    Br J Clin Pharmacol; 2023 Oct; 89(10):3175-3194. PubMed ID: 37293836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Facing the Facts of Altered Plasma Protein Binding: Do Current Models Correctly Predict Changes in Fraction Unbound in Special Populations?
    Al-Qassabi J; Tan SPF; Phonboon P; Galetin A; Rostami-Hodjegan A; Scotcher D
    J Pharm Sci; 2024 Jun; 113(6):1664-1673. PubMed ID: 38417790
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique.
    Goelen J; Farrell G; McGeehan J; Titman CM; J W Rattray N; Johnson TN; Horniblow RD; Batchelor HK
    Eur J Pharm Biopharm; 2023 Oct; 191():68-77. PubMed ID: 37625656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Building a Predictive PBPK Model for Human OATP Substrates: a Strategic Framework for Early Evaluation of Clinical Pharmacokinetic Variations Using Pitavastatin as an Example.
    Liang X; Koleske ML; Yang J; Lai Y
    AAPS J; 2024 Jan; 26(1):13. PubMed ID: 38182946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring inter-ethnic and inter-patient variability and optimal dosing of osimertinib: a physiologically based pharmacokinetic modeling approach.
    Liang F; Zhang Y; Xue Q; Yao N
    Front Pharmacol; 2024; 15():1363259. PubMed ID: 38500771
    [No Abstract]   [Full Text] [Related]  

  • 13. Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches.
    Guo Y; Chu X; Parrott NJ; Brouwer KLR; Hsu V; Nagar S; Matsson P; Sharma P; Snoeys J; Sugiyama Y; Tatosian D; Unadkat JD; Huang SM; Galetin A;
    Clin Pharmacol Ther; 2018 Nov; 104(5):865-889. PubMed ID: 30059145
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans?
    Thakur A; Yue G; Ahire D; Mettu VS; Al Maghribi A; Ford K; Peixoto L; Leeder JS; Prasad B
    Clin Pharmacol Ther; 2024 May; ():. PubMed ID: 38711199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Paediatric pharmacokinetics: key considerations.
    Batchelor HK; Marriott JF
    Br J Clin Pharmacol; 2015 Mar; 79(3):395-404. PubMed ID: 25855821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Current trends in drug metabolism and pharmacokinetics.
    Li Y; Meng Q; Yang M; Liu D; Hou X; Tang L; Wang X; Lyu Y; Chen X; Liu K; Yu AM; Zuo Z; Bi H
    Acta Pharm Sin B; 2019 Nov; 9(6):1113-1144. PubMed ID: 31867160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetic analysis across studies to drive knowledge-integration: A tutorial on individual patient data meta-analysis (IPDMA).
    van Wijk RC; Imperial MZ; Savic RM; Solans BP
    CPT Pharmacometrics Syst Pharmacol; 2023 Sep; 12(9):1187-1200. PubMed ID: 37303132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. INTEDE 2.0: the metabolic roadmap of drugs.
    Zhang Y; Liu X; Li F; Yin J; Yang H; Li X; Liu X; Chai X; Niu T; Zeng S; Jia Q; Zhu F
    Nucleic Acids Res; 2024 Jan; 52(D1):D1355-D1364. PubMed ID: 37930837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy.
    Gong C; Bertagnolli LN; Boulton DW; Coppola P
    Pharmaceutics; 2023 Nov; 15(11):. PubMed ID: 38004602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. VARIDT 3.0: the phenotypic and regulatory variability of drug transporter.
    Yin J; Chen Z; You N; Li F; Zhang H; Xue J; Ma H; Zhao Q; Yu L; Zeng S; Zhu F
    Nucleic Acids Res; 2024 Jan; 52(D1):D1490-D1502. PubMed ID: 37819041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.