These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 31276400)

  • 41. Deep Learning-Based construction of a Drug-Like compound database and its application in virtual screening of HsDHODH inhibitors.
    Xia W; Xiao J; Bian H; Zhang J; Zhang JZH; Zhang H
    Methods; 2024 May; 225():44-51. PubMed ID: 38518843
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.
    Lupo B; Vialard J; Sassi F; Angibaud P; Puliafito A; Pupo E; Lanzetti L; Comoglio PM; Bertotti A; Trusolino L
    BMC Biol; 2016 Jan; 14():5. PubMed ID: 26787475
    [TBL] [Abstract][Full Text] [Related]  

  • 43. In silico investigations on the binding efficacy and allosteric mechanism of six different natural product compounds towards PTP1B inhibition through docking and molecular dynamics simulations.
    SarathKumar B; Lakshmi BS
    J Mol Model; 2019 Aug; 25(9):272. PubMed ID: 31451955
    [TBL] [Abstract][Full Text] [Related]  

  • 44. para-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitors.
    Haikarainen T; Koivunen J; Narwal M; Venkannagari H; Obaji E; Joensuu P; Pihlajaniemi T; Lehtiö L
    ChemMedChem; 2013 Dec; 8(12):1978-85. PubMed ID: 24130191
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1.
    Yeh TY; Sbodio JI; Nguyen MT; Meyer TN; Lee RM; Chi NW
    Mol Cell Biochem; 2005 Aug; 276(1-2):183-92. PubMed ID: 16132700
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Molecular dynamics investigation on a series of HIV protease inhibitors: assessing the performance of MM-PBSA and MM-GBSA approaches.
    Srivastava HK; Sastry GN
    J Chem Inf Model; 2012 Nov; 52(11):3088-98. PubMed ID: 23121465
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Discovery of a class of novel tankyrase inhibitors that bind to both the nicotinamide pocket and the induced pocket.
    Bregman H; Gunaydin H; Gu Y; Schneider S; Wilson C; DiMauro EF; Huang X
    J Med Chem; 2013 Feb; 56(3):1341-5. PubMed ID: 23316926
    [TBL] [Abstract][Full Text] [Related]  

  • 48. 2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
    Nkizinkiko Y; Desantis J; Koivunen J; Haikarainen T; Murthy S; Sancineto L; Massari S; Ianni F; Obaji E; Loza MI; Pihlajaniemi T; Brea J; Tabarrini O; Lehtiö L
    Sci Rep; 2018 Jan; 8(1):1680. PubMed ID: 29374194
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis.
    Fujita S; Mukai T; Mito T; Kodama S; Nagasu A; Kittaka M; Sone T; Ueki Y; Morita Y
    Bone; 2018 Jan; 106():156-166. PubMed ID: 29055830
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The binding mechanism of a novel nicotinamide isostere inhibiting with TNKSs: a molecular dynamic simulation and binding free energy calculation.
    Feng TT; Zhang YJ; Chen H; Fan S; Han JG
    J Biomol Struct Dyn; 2016; 34(3):517-28. PubMed ID: 25933061
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Deep learning approaches using 2D and 3D convolutional neural networks for generating male pelvic synthetic computed tomography from magnetic resonance imaging.
    Fu J; Yang Y; Singhrao K; Ruan D; Chu FI; Low DA; Lewis JH
    Med Phys; 2019 Sep; 46(9):3788-3798. PubMed ID: 31220353
    [TBL] [Abstract][Full Text] [Related]  

  • 52. The antimitotic potential of PARP inhibitors, an unexplored therapeutic alternative.
    Iglesias P; Costoya JA
    Curr Top Med Chem; 2014; 14(20):2346-65. PubMed ID: 25434352
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Tankyrase as a Novel Molecular Target in Cancer and Fibrotic Diseases.
    Lakshmi TV; Bale S; Khurana A; Godugu C
    Curr Drug Targets; 2017; 18(10):1214-1224. PubMed ID: 27425647
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Beware of machine learning-based scoring functions-on the danger of developing black boxes.
    Gabel J; Desaphy J; Rognan D
    J Chem Inf Model; 2014 Oct; 54(10):2807-15. PubMed ID: 25207678
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Rationalizing protein-ligand interactions for PTP1B inhibitors using computational methods.
    Ajmani S; Karanam S; Kulkarni SA
    Chem Biol Drug Des; 2009 Dec; 74(6):582-95. PubMed ID: 19824894
    [TBL] [Abstract][Full Text] [Related]  

  • 56. BgN-Score and BsN-Score: bagging and boosting based ensemble neural networks scoring functions for accurate binding affinity prediction of protein-ligand complexes.
    Ashtawy HM; Mahapatra NR
    BMC Bioinformatics; 2015; 16 Suppl 4(Suppl 4):S8. PubMed ID: 25734685
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Learning molecular dynamics with simple language model built upon long short-term memory neural network.
    Tsai ST; Kuo EJ; Tiwary P
    Nat Commun; 2020 Oct; 11(1):5115. PubMed ID: 33037228
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases.
    Shultz MD; Majumdar D; Chin DN; Fortin PD; Feng Y; Gould T; Kirby CA; Stams T; Waters NJ; Shao W
    J Med Chem; 2013 Sep; 56(17):7049-59. PubMed ID: 23879431
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Fragment-based ligand design of novel potent inhibitors of tankyrases.
    Larsson EA; Jansson A; Ng FM; Then SW; Panicker R; Liu B; Sangthongpitag K; Pendharkar V; Tai SJ; Hill J; Dan C; Ho SY; Cheong WW; Poulsen A; Blanchard S; Lin GR; Alam J; Keller TH; Nordlund P
    J Med Chem; 2013 Jun; 56(11):4497-508. PubMed ID: 23672613
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Use of the Multilayer Fragment Molecular Orbital Method to Predict the Rank Order of Protein-Ligand Binding Affinities: A Case Study Using Tankyrase 2 Inhibitors.
    Okimoto N; Otsuka T; Hirano Y; Taiji M
    ACS Omega; 2018 Apr; 3(4):4475-4485. PubMed ID: 31458673
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.