BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 31282857)

  • 1. Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells.
    Brian BF; Jolicoeur AS; Guerrero CR; Nunez MG; Sychev ZE; Hegre SA; Sætrom P; Habib N; Drake JM; Schwertfeger KL; Freedman TS
    Elife; 2019 Jul; 8():. PubMed ID: 31282857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.
    Freedman TS; Tan YX; Skrzypczynska KM; Manz BN; Sjaastad FV; Goodridge HS; Lowell CA; Weiss A
    Elife; 2015 Oct; 4():. PubMed ID: 26517880
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Depletion of Csk preferentially reduces the protein level of LynA in a Cbl-dependent manner in cancer cells.
    Kuga T; Yamane Y; Hayashi S; Taniguchi M; Yamaguchi N; Yamagishi N
    Sci Rep; 2020 May; 10(1):7621. PubMed ID: 32376886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CBL mutation-related patterns of phosphorylation and sensitivity to tyrosine kinase inhibitors.
    Makishima H; Sugimoto Y; Szpurka H; Clemente MJ; Ng KP; Muramatsu H; O'Keefe C; Saunthararajah Y; Maciejewski JP
    Leukemia; 2012 Jul; 26(7):1547-54. PubMed ID: 22246246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages.
    Erdreich-Epstein A; Liu M; Kant AM; Izadi KD; Nolta JA; Durden DL
    J Leukoc Biol; 1999 Apr; 65(4):523-34. PubMed ID: 10204582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation.
    Kyo S; Sada K; Qu X; Maeno K; Miah SM; Kawauchi-Kamata K; Yamamura H
    Genes Cells; 2003 Oct; 8(10):825-36. PubMed ID: 14531861
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.
    Gustin SE; Thien CB; Langdon WY
    J Immunol; 2006 Nov; 177(9):5980-9. PubMed ID: 17056522
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.
    Masson K; Heiss E; Band H; Rönnstrand L
    Biochem J; 2006 Oct; 399(1):59-67. PubMed ID: 16780420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
    Mukhopadhyay C; Triplett A; Bargar T; Heckman C; Wagner KU; Naramura M
    Proc Natl Acad Sci U S A; 2016 Dec; 113(51):E8228-E8237. PubMed ID: 27930322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.
    Rorsman C; Tsioumpekou M; Heldin CH; Lennartsson J
    J Biol Chem; 2016 May; 291(22):11608-18. PubMed ID: 27048651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway.
    Peruzzi G; Molfetta R; Gasparrini F; Vian L; Morrone S; Piccoli M; Frati L; Santoni A; Paolini R
    J Immunol; 2007 Aug; 179(4):2089-96. PubMed ID: 17675467
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1.
    Belizaire R; Koochaki SHJ; Udeshi ND; Vedder A; Sun L; Svinkina T; Hartigan C; McConkey M; Kovalcik V; Bizuayehu A; Stanclift C; Schenone M; Carr SA; Padron E; Ebert BL
    Blood; 2021 Apr; 137(16):2209-2220. PubMed ID: 33512474
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.
    Wybenga-Groot LE; Tench AJ; Simpson CD; Germain JS; Raught B; Moran MF; McGlade CJ
    J Mol Biol; 2021 Apr; 433(8):166880. PubMed ID: 33617900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.
    Goyama S; Schibler J; Gasilina A; Shrestha M; Lin S; Link KA; Chen J; Whitman SP; Bloomfield CD; Nicolet D; Assi SA; Ptasinska A; Heidenreich O; Bonifer C; Kitamura T; Nassar NN; Mulloy JC
    Leukemia; 2016 Mar; 30(3):728-39. PubMed ID: 26449661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b.
    Qu X; Sada K; Kyo S; Maeno K; Miah SM; Yamamura H
    Blood; 2004 Mar; 103(5):1779-86. PubMed ID: 14604964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells.
    Ota Y; Beitz LO; Scharenberg AM; Donovan JA; Kinet JP; Samelson LE
    J Exp Med; 1996 Nov; 184(5):1713-23. PubMed ID: 8920860
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
    Meng F; Lowell CA
    EMBO J; 1998 Aug; 17(15):4391-403. PubMed ID: 9687507
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.
    Kaabeche K; Lemonnier J; Le Mée S; Caverzasio J; Marie PJ
    J Biol Chem; 2004 Aug; 279(35):36259-67. PubMed ID: 15190072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia.
    Gioia R; Trégoat C; Dumas PY; Lagarde V; Prouzet-Mauléon V; Desplat V; Sirvent A; Praloran V; Lippert E; Villacreces A; Leconet W; Robert B; Vigon I; Roche S; Mahon FX; Pasquet JM
    J Pathol; 2015 Sep; 237(1):14-24. PubMed ID: 25965880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway.
    Shivanna S; Harrold I; Shashar M; Meyer R; Kiang C; Francis J; Zhao Q; Feng H; Edelman ER; Rahimi N; Chitalia VC
    J Biol Chem; 2015 May; 290(20):12537-46. PubMed ID: 25784557
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.