BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 31285322)

  • 1. Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.
    Kim JH; Penson AV; Taylor BS; Petrini JHJ
    Proc Natl Acad Sci U S A; 2019 Jul; 116(30):15178-15183. PubMed ID: 31285322
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.
    Mosor M; Ziółkowska-Suchanek I; Nowicka K; Dzikiewicz-Krawczyk A; Januszkiewicz-Lewandowska D; Nowak J
    BMC Cancer; 2013 Oct; 13():457. PubMed ID: 24093751
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
    Morales M; Theunissen JW; Kim CF; Kitagawa R; Kastan MB; Petrini JH
    Genes Dev; 2005 Dec; 19(24):3043-54. PubMed ID: 16357220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
    Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
    IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
    Difilippantonio S; Celeste A; Fernandez-Capetillo O; Chen HT; Reina San Martin B; Van Laethem F; Yang YP; Petukhova GV; Eckhaus M; Feigenbaum L; Manova K; Kruhlak M; Camerini-Otero RD; Sharan S; Nussenzweig M; Nussenzweig A
    Nat Cell Biol; 2005 Jul; 7(7):675-85. PubMed ID: 15965469
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex.
    Bai Y; Wang W; Li S; Zhan J; Li H; Zhao M; Zhou XA; Li S; Li X; Huo Y; Shen Q; Zhou M; Zhang H; Luo J; Sung P; Zhu WG; Xu X; Wang J
    Mol Cell; 2019 Sep; 75(6):1299-1314.e6. PubMed ID: 31353207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.
    Song H; Hollstein M; Xu Y
    Nat Cell Biol; 2007 May; 9(5):573-80. PubMed ID: 17417627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
    Matsushita K; Kitamura K; Rahmutulla B; Tanaka N; Ishige T; Satoh M; Hoshino T; Miyagi S; Mori T; Itoga S; Shimada H; Tomonaga T; Kito M; Nakajima-Takagi Y; Kubo S; Nakaseko C; Hatano M; Miki T; Matsuo M; Fukuyo M; Kaneda A; Iwama A; Nomura F
    Oncotarget; 2015 Mar; 6(7):5102-17. PubMed ID: 25671302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.
    Spehalski E; Capper KM; Smith CJ; Morgan MJ; Dinkelmann M; Buis J; Sekiguchi JM; Ferguson DO
    Cancer Res; 2017 Oct; 77(19):5327-5338. PubMed ID: 28819025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts.
    Chang EY; Tsai S; Aristizabal MJ; Wells JP; Coulombe Y; Busatto FF; Chan YA; Kumar A; Dan Zhu Y; Wang AY; Fournier LA; Hieter P; Kobor MS; Masson JY; Stirling PC
    Nat Commun; 2019 Sep; 10(1):4265. PubMed ID: 31537797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia.
    Ge Z; Zhou X; Gu Y; Han Q; Li J; Chen B; Ge Q; Dovat E; Payne JL; Sun T; Song C; Dovat S
    Oncotarget; 2017 Jan; 8(5):8022-8034. PubMed ID: 28030830
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.
    Kim JH; Grosbart M; Anand R; Wyman C; Cejka P; Petrini JHJ
    Cell Rep; 2017 Jan; 18(2):496-507. PubMed ID: 28076792
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A murine model of Nijmegen breakage syndrome.
    Williams BR; Mirzoeva OK; Morgan WF; Lin J; Dunnick W; Petrini JH
    Curr Biol; 2002 Apr; 12(8):648-53. PubMed ID: 11967151
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
    Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
    Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1.
    Li X; Gounari F; Protopopov A; Khazaie K; von Boehmer H
    J Exp Med; 2008 Nov; 205(12):2851-61. PubMed ID: 18981238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability.
    Ham MF; Takakuwa T; Luo WJ; Liu A; Horii A; Aozasa K
    Cancer Sci; 2006 Mar; 97(3):226-34. PubMed ID: 16542220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
    Witkowski MT; Cimmino L; Hu Y; Trimarchi T; Tagoh H; McKenzie MD; Best SA; Tuohey L; Willson TA; Nutt SL; Busslinger M; Aifantis I; Smyth GK; Dickins RA
    Leukemia; 2015 Jun; 29(6):1301-11. PubMed ID: 25655195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MRN Complex and Cancer Risk: Old Bottles, New Wine.
    Elkholi IE; Foulkes WD; Rivera B
    Clin Cancer Res; 2021 Oct; 27(20):5465-5471. PubMed ID: 34261697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model.
    Balestrini A; Nicolas L; Yang-Lott K; Guryanova OA; Levine RL; Bassing CH; Chaudhuri J; Petrini JH
    Mol Cancer Res; 2016 Feb; 14(2):185-95. PubMed ID: 26538284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.
    de Bock CE; Down M; Baidya K; Sweron B; Boyd AW; Fiers M; Burns GF; Molloy TJ; Lock RB; Soulier J; Taghon T; Van Vlierberghe P; Cools J; Holst J; Thorne RF
    Haematologica; 2019 May; 104(5):e204-e207. PubMed ID: 30514801
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.