232 related articles for article (PubMed ID: 31285607)
1. Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Zhu X; Clarke R; Puppala AK; Chittori S; Merk A; Merrill BJ; Simonović M; Subramaniam S
Nat Struct Mol Biol; 2019 Aug; 26(8):679-685. PubMed ID: 31285607
[TBL] [Abstract][Full Text] [Related]
2. R-loop formation and conformational activation mechanisms of Cas9.
Pacesa M; Loeff L; Querques I; Muckenfuss LM; Sawicka M; Jinek M
Nature; 2022 Sep; 609(7925):191-196. PubMed ID: 36002571
[TBL] [Abstract][Full Text] [Related]
3. Real-time observation of Cas9 postcatalytic domain motions.
Wang Y; Mallon J; Wang H; Singh D; Hyun Jo M; Hua B; Bailey S; Ha T
Proc Natl Acad Sci U S A; 2021 Jan; 118(2):. PubMed ID: 33443184
[TBL] [Abstract][Full Text] [Related]
4. The final cut: Cas9 editing.
Taylor DW
Nat Struct Mol Biol; 2019 Aug; 26(8):669-670. PubMed ID: 31285603
[No Abstract] [Full Text] [Related]
5. Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Sun W; Yang J; Cheng Z; Amrani N; Liu C; Wang K; Ibraheim R; Edraki A; Huang X; Wang M; Wang J; Liu L; Sheng G; Yang Y; Lou J; Sontheimer EJ; Wang Y
Mol Cell; 2019 Dec; 76(6):938-952.e5. PubMed ID: 31668930
[TBL] [Abstract][Full Text] [Related]
6. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.
Babu K; Kathiresan V; Kumari P; Newsom S; Parameshwaran HP; Chen X; Liu J; Qin PZ; Rajan R
Biochemistry; 2021 Dec; 60(49):3783-3800. PubMed ID: 34757726
[TBL] [Abstract][Full Text] [Related]
7. Structural and functional insights into the
Zuo Z; Zolekar A; Babu K; Lin VJ; Hayatshahi HS; Rajan R; Wang YC; Liu J
Elife; 2019 Jul; 8():. PubMed ID: 31361218
[TBL] [Abstract][Full Text] [Related]
8. Structural insights into DNA cleavage activation of CRISPR-Cas9 system.
Huai C; Li G; Yao R; Zhang Y; Cao M; Kong L; Jia C; Yuan H; Chen H; Lu D; Huang Q
Nat Commun; 2017 Nov; 8(1):1375. PubMed ID: 29123204
[TBL] [Abstract][Full Text] [Related]
9. Exploring alternative catalytic mechanisms of the Cas9 HNH domain.
Zhao LN; Mondal D; Warshel A
Proteins; 2020 Feb; 88(2):260-264. PubMed ID: 31390092
[TBL] [Abstract][Full Text] [Related]
10. Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate Off-Target Effects.
Maghsoud Y; Jayasinghe-Arachchige VM; Kumari P; Cisneros GA; Liu J
J Chem Inf Model; 2023 Nov; 63(21):6834-6850. PubMed ID: 37877218
[TBL] [Abstract][Full Text] [Related]
11. Probing the Dynamics of
Zhdanova PV; Chernonosov AA; Prokhorova DV; Stepanov GA; Kanazhevskaya LY; Koval VV
Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163047
[TBL] [Abstract][Full Text] [Related]
12. The initiation, propagation and dynamics of CRISPR-SpyCas9 R-loop complex.
Zeng Y; Cui Y; Zhang Y; Zhang Y; Liang M; Chen H; Lan J; Song G; Lou J
Nucleic Acids Res; 2018 Jan; 46(1):350-361. PubMed ID: 29145633
[TBL] [Abstract][Full Text] [Related]
13. Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules.
Shams A; Higgins SA; Fellmann C; Laughlin TG; Oakes BL; Lew R; Kim S; Lukarska M; Arnold M; Staahl BT; Doudna JA; Savage DF
Nat Commun; 2021 Sep; 12(1):5664. PubMed ID: 34580310
[TBL] [Abstract][Full Text] [Related]
14. Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Jiang F; Taylor DW; Chen JS; Kornfeld JE; Zhou K; Thompson AJ; Nogales E; Doudna JA
Science; 2016 Feb; 351(6275):867-71. PubMed ID: 26841432
[TBL] [Abstract][Full Text] [Related]
15. Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
Jiang F; Liu JJ; Osuna BA; Xu M; Berry JD; Rauch BJ; Nogales E; Bondy-Denomy J; Doudna JA
Mol Cell; 2019 Feb; 73(3):601-610.e5. PubMed ID: 30595438
[TBL] [Abstract][Full Text] [Related]
16. Structural and dynamic insights into the HNH nuclease of divergent Cas9 species.
Belato HB; D'Ordine AM; Nierzwicki L; Arantes PR; Jogl G; Palermo G; Lisi GP
J Struct Biol; 2022 Mar; 214(1):107814. PubMed ID: 34871741
[TBL] [Abstract][Full Text] [Related]
17. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9.
Raper AT; Stephenson AA; Suo Z
J Am Chem Soc; 2018 Feb; 140(8):2971-2984. PubMed ID: 29442507
[TBL] [Abstract][Full Text] [Related]
18. Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State.
Du W; Zhu H; Qian J; Xue D; Zheng S; Huang Q
Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674715
[No Abstract] [Full Text] [Related]
19. A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9.
Dagdas YS; Chen JS; Sternberg SH; Doudna JA; Yildiz A
Sci Adv; 2017 Aug; 3(8):eaao0027. PubMed ID: 28808686
[TBL] [Abstract][Full Text] [Related]
20.
Belato HB; East KW; Lisi GP
Biomol NMR Assign; 2019 Oct; 13(2):367-370. PubMed ID: 31377985
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
