These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 31286304)

  • 1. Development and Qualification of a Scale-Down Mammalian Cell Culture Model and Application in Design Space Development by Definitive Screening Design.
    Nie L; Gao D; Jiang H; Gou J; Li L; Hu F; Guo T; Wang H; Qu H
    AAPS PharmSciTech; 2019 Jul; 20(6):246. PubMed ID: 31286304
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Application of a quality by design approach to the cell culture process of monoclonal antibody production, resulting in the establishment of a design space.
    Nagashima H; Watari A; Shinoda Y; Okamoto H; Takuma S
    J Pharm Sci; 2013 Dec; 102(12):4274-83. PubMed ID: 24122699
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Application of bioreactor design principles and multivariate analysis for development of cell culture scale down models.
    Tescione L; Lambropoulos J; Paranandi MR; Makagiansar H; Ryll T
    Biotechnol Bioeng; 2015 Jan; 112(1):84-97. PubMed ID: 25042258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of a scale down cell culture model using multivariate analysis as a qualification tool.
    Tsang VL; Wang AX; Yusuf-Makagiansar H; Ryll T
    Biotechnol Prog; 2014; 30(1):152-60. PubMed ID: 24124180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Scale-down model qualification of ambr® 250 high-throughput mini-bioreactor system for two commercial-scale mAb processes.
    Manahan M; Nelson M; Cacciatore JJ; Weng J; Xu S; Pollard J
    Biotechnol Prog; 2019 Nov; 35(6):e2870. PubMed ID: 31207168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of Tubespins as a suitable scale-down model of bioreactors for high cell density CHO cell culture.
    Gomez N; Ambhaikar M; Zhang L; Huang CJ; Barkhordarian H; Lull J; Gutierrez C
    Biotechnol Prog; 2017 Mar; 33(2):490-499. PubMed ID: 27977914
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A systematic approach for scale-down model development and characterization of commercial cell culture processes.
    Li F; Hashimura Y; Pendleton R; Harms J; Collins E; Lee B
    Biotechnol Prog; 2006; 22(3):696-703. PubMed ID: 16739951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development.
    Janakiraman V; Kwiatkowski C; Kshirsagar R; Ryll T; Huang YM
    Biotechnol Prog; 2015; 31(6):1623-32. PubMed ID: 26317495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Application of multivariate analysis and mass transfer principles for refinement of a 3-L bioreactor scale-down model--when shake flasks mimic 15,000-L bioreactors better.
    Ahuja S; Jain S; Ram K
    Biotechnol Prog; 2015; 31(5):1370-80. PubMed ID: 26097232
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and qualification of 3 L scale-down model for large scale vaccine process on Vero cell culture using microcarriers.
    Huang R; Wang K; Flamm MH; Vazquez J; Gercke C; Ton C; Whitmer T; Mathis PK; Ploeger KJM; Rameez S
    Biotechnol Bioeng; 2024 Nov; 121(11):3402-3414. PubMed ID: 38993032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells.
    Legmann R; Schreyer HB; Combs RG; McCormick EL; Russo AP; Rodgers ST
    Biotechnol Bioeng; 2009 Dec; 104(6):1107-20. PubMed ID: 19623562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of the interactions of critical scale-up parameters (pH, pO
    Brunner M; Fricke J; Kroll P; Herwig C
    Bioprocess Biosyst Eng; 2017 Feb; 40(2):251-263. PubMed ID: 27752770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The impact of pH inhomogeneities on CHO cell physiology and fed-batch process performance - two-compartment scale-down modelling and intracellular pH excursion.
    Brunner M; Braun P; Doppler P; Posch C; Behrens D; Herwig C; Fricke J
    Biotechnol J; 2017 Jul; 12(7):. PubMed ID: 28078826
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemometrics and in-line near infrared spectroscopic monitoring of a biopharmaceutical Chinese hamster ovary cell culture: prediction of multiple cultivation variables.
    Clavaud M; Roggo Y; Von Daeniken R; Liebler A; Schwabe JO
    Talanta; 2013 Jul; 111():28-38. PubMed ID: 23622522
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development.
    Wang Z; Wang C; Chen G
    Protein Expr Purif; 2022 Oct; 198():106130. PubMed ID: 35691496
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cross-scale predictive modeling of CHO cell culture growth and metabolites using Raman spectroscopy and multivariate analysis.
    Berry B; Moretto J; Matthews T; Smelko J; Wiltberger K
    Biotechnol Prog; 2015; 31(2):566-77. PubMed ID: 25504860
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein.
    Looby M; Ibarra N; Pierce JJ; Buckley K; O'Donovan E; Heenan M; Moran E; Farid SS; Baganz F
    Biotechnol Prog; 2011; 27(6):1718-29. PubMed ID: 21948302
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a monoclonal antibody cell culture production process using a quality by design approach.
    Horvath B; Mun M; Laird MW
    Mol Biotechnol; 2010 Jul; 45(3):203-6. PubMed ID: 20300882
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of a shake tube-based scale-down model for perfusion cultures.
    Wolf MKF; Lorenz V; Karst DJ; Souquet J; Broly H; Morbidelli M
    Biotechnol Bioeng; 2018 Nov; 115(11):2703-2713. PubMed ID: 30039852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of bioreactor scale-down model using orthogonal projections to latent structures method and CO
    Gao J; Hazeltine LB; Stroud N; Liu N; Huang YM
    Biotechnol Prog; 2024; 40(3):e3423. PubMed ID: 38289180
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.