BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 31287365)

  • 1. DNA-dependent protein kinase: effect on DSB repair, G2/M checkpoint and mode of cell death in NSCLC cell lines.
    Sak A; Groneberg M; Stuschke M
    Int J Radiat Biol; 2019 Sep; 95(9):1205-1219. PubMed ID: 31287365
    [No Abstract]   [Full Text] [Related]  

  • 2. Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase.
    Amrein L; Loignon M; Goulet AC; Dunn M; Jean-Claude B; Aloyz R; Panasci L
    J Pharmacol Exp Ther; 2007 Jun; 321(3):848-55. PubMed ID: 17351105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair.
    Sunada S; Kanai H; Lee Y; Yasuda T; Hirakawa H; Liu C; Fujimori A; Uesaka M; Okayasu R
    Cancer Sci; 2016 Sep; 107(9):1250-5. PubMed ID: 27341700
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor.
    Yu L; Shang ZF; Hsu FM; Zhang Z; Tumati V; Lin YF; Chen BP; Saha D
    Oncotarget; 2015 Feb; 6(6):3848-60. PubMed ID: 25714019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Co-targeting deoxyribonucleic acid-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 promotes accelerated senescence of irradiated cancer cells.
    Azad A; Bukczynska P; Jackson S; Haupt Y; Cullinane C; McArthur GA; Solomon B
    Int J Radiat Oncol Biol Phys; 2014 Feb; 88(2):385-94. PubMed ID: 24411611
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair.
    Gustafsson AS; Abramenkovs A; Stenerlöw B
    Mutat Res; 2014 Nov; 769():1-10. PubMed ID: 25771720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
    An J; Huang YC; Xu QZ; Zhou LJ; Shang ZF; Huang B; Wang Y; Liu XD; Wu DC; Zhou PK
    BMC Mol Biol; 2010 Mar; 11():18. PubMed ID: 20205745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.
    Urushihara Y; Kobayashi J; Matsumoto Y; Komatsu K; Oda S; Mitani H
    Biochem Biophys Res Commun; 2012 Dec; 429(3-4):131-6. PubMed ID: 23142596
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.
    Toulany M; Kehlbach R; Florczak U; Sak A; Wang S; Chen J; Lobrich M; Rodemann HP
    Mol Cancer Ther; 2008 Jul; 7(7):1772-81. PubMed ID: 18644989
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA double-strand break repair and induction of apoptosis in ex vivo irradiated blood lymphocytes in relation to late normal tissue reactions following breast radiotherapy.
    Chua ML; Horn S; Somaiah N; Davies S; Gothard L; A'Hern R; Yarnold J; Rothkamm K
    Radiat Environ Biophys; 2014 May; 53(2):355-64. PubMed ID: 24622963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks.
    Dong J; Zhang T; Ren Y; Wang Z; Ling CC; He F; Li GC; Wang C; Wen B
    Oncotarget; 2017 Apr; 8(14):22662-22673. PubMed ID: 28186989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression.
    Bee L; Fabris S; Cherubini R; Mognato M; Celotti L
    PLoS One; 2013; 8(7):e69061. PubMed ID: 23874869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition.
    Ćmielová J; Havelek R; Vávrová J; Řezáčová M
    Med Oncol; 2015 May; 32(5):138. PubMed ID: 25801233
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814.
    Sun Q; Guo Y; Liu X; Czauderna F; Carr MI; Zenke FT; Blaukat A; Vassilev LT
    Mol Cancer Res; 2019 Dec; 17(12):2457-2468. PubMed ID: 31551253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radiation-induced apoptosis in human non-small-cell lung cancer cell lines is secondary to cell-cycle progression beyond the G2-phase checkpoint.
    Stuschke M; Sak A; Wurm R; Sinn B; Wolf G; Stüben G; Budach V
    Int J Radiat Biol; 2002 Sep; 78(9):807-19. PubMed ID: 12428922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.
    Inturi S; Tewari-Singh N; Agarwal C; White CW; Agarwal R
    Mutat Res; 2014; 763-764():53-63. PubMed ID: 24732344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
    Liu Y; Efimova EV; Ramamurthy A; Kron SJ
    J Cell Sci; 2019 Jul; 132(13):. PubMed ID: 31189537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of DNA-dependent protein kinase catalytic subunit by small molecule inhibitor NU7026 sensitizes human leukemic K562 cells to benzene metabolite-induced apoptosis.
    You H; Kong MM; Wang LP; Xiao X; Liao HL; Bi ZY; Yan H; Wang H; Wang CH; Ma Q; Liu YQ; Bi YY
    J Huazhong Univ Sci Technolog Med Sci; 2013 Feb; 33(1):43-50. PubMed ID: 23392706
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NU7441 Enhances the Radiosensitivity of Liver Cancer Cells.
    Yang C; Wang Q; Liu X; Cheng X; Jiang X; Zhang Y; Feng Z; Zhou P
    Cell Physiol Biochem; 2016; 38(5):1897-905. PubMed ID: 27160694
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancement of Radiosensitivity by Eurycomalactone in Human NSCLC Cells Through G₂/M Cell Cycle Arrest and Delayed DNA Double-Strand Break Repair.
    Dukaew N; Konishi T; Chairatvit K; Autsavapromporn N; Soonthornchareonnon N; Wongnoppavich A
    Oncol Res; 2020 Mar; 28(2):161-175. PubMed ID: 31727206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.