BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 31299612)

  • 1. Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1.
    Pickel C; Günter J; Ruiz-Serrano A; Spielmann P; Fabrizio JA; Wolski W; Peet DJ; Wenger RH; Scholz CC
    Redox Biol; 2019 Sep; 26():101265. PubMed ID: 31299612
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.
    Scholz CC; Rodriguez J; Pickel C; Burr S; Fabrizio JA; Nolan KA; Spielmann P; Cavadas MA; Crifo B; Halligan DN; Nathan JA; Peet DJ; Wenger RH; Von Kriegsheim A; Cummins EP; Taylor CT
    PLoS Biol; 2016 Jan; 14(1):e1002347. PubMed ID: 26752685
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxomer- and Reporter Gene-Based Analysis of FIH Activity in Cells.
    Volkova YL; Jucht AE; Scholz CC
    Methods Mol Biol; 2024; 2755():249-264. PubMed ID: 38319583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Asparagine Hydroxylase FIH: A Unique Oxygen Sensor.
    Volkova YL; Pickel C; Jucht AE; Wenger RH; Scholz CC
    Antioxid Redox Signal; 2022 Nov; 37(13-15):913-935. PubMed ID: 35166119
    [No Abstract]   [Full Text] [Related]  

  • 5. Selective Hypoxia-Sensitive Oxomer Formation by FIH Prevents Binding of the NF-κB Inhibitor IκBβ to NF-κB Subunits.
    Volkova YL; Jucht AE; Oechsler N; Krishnankutty R; von Kriegsheim A; Wenger RH; Scholz CC
    Mol Cell Biol; 2024; 44(4):138-148. PubMed ID: 38644795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signalling cross talk of the HIF system: involvement of the FIH protein.
    Coleman ML; Ratcliffe PJ
    Curr Pharm Des; 2009; 15(33):3904-7. PubMed ID: 19671041
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
    Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
    J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
    Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
    J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation.
    Liu X; Deng H; Tang J; Wang Z; Zhu C; Cai X; Rong F; Chen X; Sun X; Jia S; Ouyang G; Li W; Xiao W
    Cell Death Dis; 2022 Jun; 13(6):560. PubMed ID: 35732631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells.
    Kim I; Shin SH; Lee JE; Park JW
    Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
    Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
    Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism.
    Ruiz-Serrano A; Boyle CN; Monné Rodríguez JM; Günter J; Jucht AE; Pfundstein S; Bapst AM; Lutz TA; Wenger RH; Scholz CC
    Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163456
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
    Strowitzki MJ; Cummins EP; Taylor CT
    Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
    Cockman ME; Webb JD; Kramer HB; Kessler BM; Ratcliffe PJ
    Mol Cell Proteomics; 2009 Mar; 8(3):535-46. PubMed ID: 18936059
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
    Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
    J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
    Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
    FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of HIF: asparaginyl hydroxylation.
    Peet D; Linke S
    Novartis Found Symp; 2006; 272():37-49; discussion 49-53, 131-40. PubMed ID: 16686428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.