BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

428 related articles for article (PubMed ID: 31300611)

  • 21. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
    Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ascofuranone suppresses EGF-induced HIF-1α protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells.
    Jeong YJ; Cho HJ; Magae J; Lee IK; Park KG; Chang YC
    Toxicol Appl Pharmacol; 2013 Dec; 273(3):542-50. PubMed ID: 24096035
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Retinoblastoma binding protein 2 (RBP2) promotes HIF-1α-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway.
    Qi L; Zhu F; Li SH; Si LB; Hu LK; Tian H
    PLoS One; 2014; 9(8):e106032. PubMed ID: 25162518
    [TBL] [Abstract][Full Text] [Related]  

  • 24. HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).
    De Francesco EM; Lappano R; Santolla MF; Marsico S; Caruso A; Maggiolini M
    Breast Cancer Res; 2013; 15(4):R64. PubMed ID: 23947803
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia-inducible factor-1α activation.
    Thapa D; Kang Y; Park PH; Noh SK; Lee YR; Han SS; Ku SK; Jung Y; Kim JA
    Biol Pharm Bull; 2012; 35(6):924-32. PubMed ID: 22687485
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells.
    Ciccone V; Terzuoli E; Donnini S; Giachetti A; Morbidelli L; Ziche M
    J Exp Clin Cancer Res; 2018 Dec; 37(1):311. PubMed ID: 30541574
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells.
    Tomita M; Semenza GL; Michiels C; Matsuda T; Uchihara JN; Okudaira T; Tanaka Y; Taira N; Ohshiro K; Mori N
    Biochem J; 2007 Sep; 406(2):317-23. PubMed ID: 17576198
    [TBL] [Abstract][Full Text] [Related]  

  • 28. High-Mobility Group Box 1 (HMGB1) Promotes Angiogenesis and Tumor Migration by Regulating Hypoxia-Inducible Factor 1 (HIF-1α) Expression via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Signaling Pathway in Breast Cancer Cells.
    He H; Wang X; Chen J; Sun L; Sun H; Xie K
    Med Sci Monit; 2019 Apr; 25():2352-2360. PubMed ID: 30930461
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phosphatidylinositol 3'-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1(alpha) and vascular endothelial growth factor expression.
    Xue Y; Li NL; Yang JY; Chen Y; Yang LL; Liu WC
    Am J Physiol Heart Circ Physiol; 2011 Jun; 300(6):H2169-76. PubMed ID: 21357506
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Role of HIF-1alpha and VEGF in human mesenchymal stem cell proliferation by 17beta-estradiol: involvement of PKC, PI3K/Akt, and MAPKs.
    Yun SP; Lee MY; Ryu JM; Song CH; Han HJ
    Am J Physiol Cell Physiol; 2009 Feb; 296(2):C317-26. PubMed ID: 18987249
    [TBL] [Abstract][Full Text] [Related]  

  • 31. UVB radiation induces expression of HIF-1alpha and VEGF through the EGFR/PI3K/DEC1 pathway.
    Li Y; Bi Z; Yan B; Wan Y
    Int J Mol Med; 2006 Oct; 18(4):713-9. PubMed ID: 16964427
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro.
    Fernand VE; Losso JN; Truax RE; Villar EE; Bwambok DK; Fakayode SO; Lowry M; Warner IM
    Chem Biol Interact; 2011 Jul; 192(3):220-32. PubMed ID: 21457705
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.
    Yang XM; Wang YS; Zhang J; Li Y; Xu JF; Zhu J; Zhao W; Chu DK; Wiedemann P
    Invest Ophthalmol Vis Sci; 2009 Apr; 50(4):1873-9. PubMed ID: 19098317
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patient with acute leukemia via inhibiting the activation of PI3K/Akt and ERK1/2 pathways.
    Zeng D; Wang J; Kong P; Chang C; Li J; Li J
    Int J Clin Exp Pathol; 2014; 7(5):2172-8. PubMed ID: 24966925
    [TBL] [Abstract][Full Text] [Related]  

  • 35. NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms.
    Zhong H; Willard M; Simons J
    Int J Cancer; 2004 Nov; 112(4):585-95. PubMed ID: 15382039
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Stathmin, a microtubule regulatory protein, is associated with hypoxia-inducible factor-1alpha levels in human endometrial and endothelial cells.
    Yoshie M; Miyajima E; Kyo S; Tamura K
    Endocrinology; 2009 May; 150(5):2413-8. PubMed ID: 19179443
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase/Akt pathway.
    Kazi AA; Koos RD
    Endocrinology; 2007 May; 148(5):2363-74. PubMed ID: 17272396
    [TBL] [Abstract][Full Text] [Related]  

  • 38. C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways.
    Chen J; Gu Z; Wu M; Yang Y; Zhang J; Ou J; Zuo Z; Wang J; Chen Y
    Stem Cell Res Ther; 2016 Aug; 7(1):114. PubMed ID: 27526687
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.
    Han X; Sun S; Zhao M; Cheng X; Chen G; Lin S; Guan Y; Yu X
    PLoS One; 2014; 9(11):e112470. PubMed ID: 25383959
    [TBL] [Abstract][Full Text] [Related]  

  • 40. delta opioid receptors stimulate Akt-dependent phosphorylation of c-jun in T cells.
    Shahabi NA; McAllen K; Sharp BM
    J Pharmacol Exp Ther; 2006 Feb; 316(2):933-9. PubMed ID: 16249373
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.