BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 31300647)

  • 1. Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation.
    Park JS; Lee J; Jung ES; Kim MH; Kim IB; Son H; Kim S; Kim S; Park YM; Mook-Jung I; Yu SJ; Lee JH
    Nat Commun; 2019 Jul; 10(1):3090. PubMed ID: 31300647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease.
    Poli M; Gatta LB; Dominici R; Lovati C; Mariani C; Albertini A; Finazzi D
    Neurosci Lett; 2005 Dec; 389(2):66-70. PubMed ID: 16095818
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Death-associated protein kinase 1 mediates Aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in Alzheimer's disease.
    Zhang T; Xia Y; Hu L; Chen D; Gan CL; Wang L; Mei Y; Lan G; Shui X; Tian Y; Li R; Zhang M; Lee TH
    Int J Biol Sci; 2022; 18(2):693-706. PubMed ID: 35002518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.
    Kim BM; You MH; Chen CH; Lee S; Hong Y; Hong Y; Kimchi A; Zhou XZ; Lee TH
    Cell Death Dis; 2014 May; 5(5):e1237. PubMed ID: 24853415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The significance of Pin1 in the development of Alzheimer's disease.
    Wang S; Simon BP; Bennett DA; Schneider JA; Malter JS; Wang DS
    J Alzheimers Dis; 2007 Mar; 11(1):13-23. PubMed ID: 17361031
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system.
    Tackenberg C; Kulic L; Nitsch RM
    PLoS One; 2020; 15(9):e0239584. PubMed ID: 32966331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.
    Xu L; Ren Z; Chow FE; Tsai R; Liu T; Rizzolio F; Boffo S; Xu Y; Huang S; Lippa CF; Gong Y
    Neural Plast; 2017; 2017():3270725. PubMed ID: 28458925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pin1 Knockout Mice: A Model for the Study of Tau Pathology in Alzheimer's Disease.
    Kondo A; Albayram O; Zhou XZ; Lu KP
    Methods Mol Biol; 2017; 1523():415-425. PubMed ID: 27975268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies.
    Ramakrishnan P; Dickson DW; Davies P
    Neurobiol Dis; 2003 Nov; 14(2):251-64. PubMed ID: 14572447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of presenilin function enhances tau phosphorylation and aggregation in mice.
    Soto-Faguás CM; Sanchez-Molina P; Saura CA
    Acta Neuropathol Commun; 2021 Sep; 9(1):162. PubMed ID: 34593029
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.
    Ueberham U; Rohn S; Ueberham E; Wodischeck S; Hilbrich I; Holzer M; Brückner MK; Gruschka H; Arendt T
    Neuropathol Appl Neurobiol; 2014 Dec; 40(7):815-32. PubMed ID: 24964035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Okadaic acid-induced tau hyperphosphorylation and the downregulation of Pin1 expression in primary cortical neurons.
    Metin-Armağan D; Gezen-Ak D; Dursun E; Atasoy İL; Karabay A; Yılmazer S; Öztürk M
    J Chem Neuroanat; 2018 Oct; 92():41-47. PubMed ID: 29860071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p73 haploinsufficiency causes tau hyperphosphorylation and tau kinase dysregulation in mouse models of aging and Alzheimer's disease.
    Cancino GI; Miller FD; Kaplan DR
    Neurobiol Aging; 2013 Feb; 34(2):387-99. PubMed ID: 22592019
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus.
    Holzer M; Gärtner U; Stöbe A; Härtig W; Gruschka H; Brückner MK; Arendt T
    Acta Neuropathol; 2002 Nov; 104(5):471-81. PubMed ID: 12410395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.
    Kimura T; Tsutsumi K; Taoka M; Saito T; Masuda-Suzukake M; Ishiguro K; Plattner F; Uchida T; Isobe T; Hasegawa M; Hisanaga SI
    J Biol Chem; 2013 Mar; 288(11):7968-7977. PubMed ID: 23362255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neurotoxicity of oligomers of phosphorylated Tau protein carrying tauopathy-associated mutation is inhibited by prion protein.
    Nieznanska H; Boyko S; Dec R; Redowicz MJ; Dzwolak W; Nieznanski K
    Biochim Biophys Acta Mol Basis Dis; 2021 Nov; 1867(11):166209. PubMed ID: 34246750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of glycogen synthase kinase-3 reverses tau hyperphosphorylation induced by Pin1 down-regulation.
    Xiong YS; Wang DL; Tan L; Wang X; Chen LM; Gong CX; Wang JZ; Zhu LQ
    CNS Neurol Disord Drug Targets; 2013 May; 12(3):436-43. PubMed ID: 23469846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct functions of cis and trans phosphorylated tau in Alzheimer's disease and their therapeutic implications.
    Nakamura K; Zhou XZ; Lu KP
    Curr Mol Med; 2013 Aug; 13(7):1098-109. PubMed ID: 23157676
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.
    Hall EC; Lee SY; Simmons Z; Neely EB; Nandar W; Connor JR
    Biochim Biophys Acta; 2010 Apr; 1802(4):389-95. PubMed ID: 20060900
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
    Ando K; Dourlen P; Sambo AV; Bretteville A; Bélarbi K; Vingtdeux V; Eddarkaoui S; Drobecq H; Ghestem A; Bégard S; Demey-Thomas E; Melnyk P; Smet C; Lippens G; Maurage CA; Caillet-Boudin ML; Verdier Y; Vinh J; Landrieu I; Galas MC; Blum D; Hamdane M; Sergeant N; Buée L
    Neurobiol Aging; 2013 Mar; 34(3):757-69. PubMed ID: 22926167
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.