These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 31307583)

  • 1. Primary hepatocytes and their cultures for the testing of drug-induced liver injury.
    Vilas-Boas V; Cooreman A; Gijbels E; Van Campenhout R; Gustafson E; Ballet S; Annaert P; Cogliati B; Vinken M
    Adv Pharmacol; 2019; 85():1-30. PubMed ID: 31307583
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inter-individual differences in the susceptibility of primary human hepatocytes towards drug-induced cholestasis are compound and time dependent.
    Parmentier C; Hendriks DFG; Heyd B; Bachellier P; Ingelman-Sundberg M; Richert L
    Toxicol Lett; 2018 Oct; 295():187-194. PubMed ID: 29913214
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity.
    Meng Q
    Expert Opin Drug Metab Toxicol; 2010 Jun; 6(6):733-46. PubMed ID: 20380484
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Detection of Drug-Induced Cholestasis Potential in Sandwich-Cultured Human Hepatocytes.
    Deferm N; Richert L; Van Brantegem P; De Vocht T; Qi B; de Witte P; Bouillon T; Annaert P
    Methods Mol Biol; 2019; 1981():335-350. PubMed ID: 31016665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.
    Kim JH; Wang M; Lee J; Park HJ; Han C; Hong HS; Kim JS; An GH; Park K; Park HK; Zhu SF; Sun XB; Kim JH; Woo DH
    Cell Biol Toxicol; 2018 Feb; 34(1):51-64. PubMed ID: 28382404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.
    Van den Hof WFPM; Coonen MLJ; van Herwijnen M; Brauers K; Jennen D; Olde Damink SWM; Schaap FG; Kleinjans JCS
    Toxicol In Vitro; 2017 Oct; 44():322-329. PubMed ID: 28778767
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles.
    Zhang J; Doshi U; Suzuki A; Chang CW; Borlak J; Li AP; Tong W
    Chem Biol Interact; 2016 Aug; 255():3-11. PubMed ID: 26581450
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
    Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
    Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolution of Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.
    Andersson TB
    Basic Clin Pharmacol Toxicol; 2017 Oct; 121(4):234-238. PubMed ID: 28470941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Long-enduring primary hepatocyte-based co-cultures improve prediction of hepatotoxicity.
    Novik EI; Dwyer J; Morelli JK; Parekh A; Cho C; Pludwinski E; Shrirao A; Freedman RM; MacDonald JS; Jayyosi Z
    Toxicol Appl Pharmacol; 2017 Dec; 336():20-30. PubMed ID: 28942002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis.
    Ramaiahgari SC; Ferguson SS
    Methods Mol Biol; 2019; 1981():313-323. PubMed ID: 31016663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
    Gómez-Lechón MJ; Tolosa L
    Arch Toxicol; 2016 Sep; 90(9):2049-2061. PubMed ID: 27325232
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.
    Ware BR; Berger DR; Khetani SR
    Toxicol Sci; 2015 Jun; 145(2):252-62. PubMed ID: 25716675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.
    Vorrink SU; Zhou Y; Ingelman-Sundberg M; Lauschke VM
    Toxicol Sci; 2018 Jun; 163(2):655-665. PubMed ID: 29590495
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Competency of different cell models to predict human hepatotoxic drugs.
    Gómez-Lechón MJ; Tolosa L; Conde I; Donato MT
    Expert Opin Drug Metab Toxicol; 2014 Nov; 10(11):1553-68. PubMed ID: 25297626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.
    Proctor WR; Foster AJ; Vogt J; Summers C; Middleton B; Pilling MA; Shienson D; Kijanska M; Ströbel S; Kelm JM; Morgan P; Messner S; Williams D
    Arch Toxicol; 2017 Aug; 91(8):2849-2863. PubMed ID: 28612260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Establishment of Sandwich Cultures of Primary Human Hepatocytes.
    Gijbels E; Vanhaecke T; Vinken M
    Methods Mol Biol; 2019; 1981():325-333. PubMed ID: 31016664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Primary hepatocyte cultures as in vitro tools for toxicity testing: quo vadis?
    Vinken M; Vanhaecke T; Rogiers V
    Toxicol In Vitro; 2012 Apr; 26(3):541-4. PubMed ID: 22261203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptomic Analysis of Cholestatic Compounds In Vitro.
    Parmentier C; Couttet P; Uteng M; Wolf A; Richert L
    Methods Mol Biol; 2019; 1981():175-186. PubMed ID: 31016655
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.
    Fraczek J; Bolleyn J; Vanhaecke T; Rogiers V; Vinken M
    Arch Toxicol; 2013 Apr; 87(4):577-610. PubMed ID: 23242478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.