These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 31311960)

  • 1. Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production.
    Gibbons HR; Mi DJ; Farley VM; Esmond T; Kaood MB; Aune TM
    Sci Rep; 2019 Jul; 9(1):10280. PubMed ID: 31311960
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.
    Donato E; Croci O; Sabò A; Muller H; Morelli MJ; Pelizzola M; Campaner S
    Leukemia; 2017 Feb; 31(2):479-490. PubMed ID: 27443262
    [TBL] [Abstract][Full Text] [Related]  

  • 3. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
    Handoko L; Kaczkowski B; Hon CC; Lizio M; Wakamori M; Matsuda T; Ito T; Jeyamohan P; Sato Y; Sakamoto K; Yokoyama S; Kimura H; Minoda A; Umehara T
    Epigenetics; 2018; 13(4):410-431. PubMed ID: 30080437
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.
    Shahbazi J; Liu PY; Atmadibrata B; Bradner JE; Marshall GM; Lock RB; Liu T
    Clin Cancer Res; 2016 May; 22(10):2534-44. PubMed ID: 26733615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered regulation and expression of genes by BET family of proteins in COPD patients.
    Malhotra R; Kurian N; Zhou XH; Jiang F; Monkley S; DeMicco A; Clausen IG; Dellgren G; Edenro G; Ahdesmäki MJ; Clausen M; Öberg L; Israelsson E; Belfield G; Vaarala O
    PLoS One; 2017; 12(3):e0173115. PubMed ID: 28248992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.
    Cribbs AP; Filippakopoulos P; Philpott M; Wells G; Penn H; Oerum H; Valge-Archer V; Feldmann M; Oppermann U
    Front Immunol; 2021; 12():626255. PubMed ID: 33717143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.
    Belkina AC; Nikolajczyk BS; Denis GV
    J Immunol; 2013 Apr; 190(7):3670-8. PubMed ID: 23420887
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.
    Decker TM; Kluge M; Krebs S; Shah N; Blum H; Friedel CC; Eick D
    Sci Rep; 2017 May; 7(1):1684. PubMed ID: 28490802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Effect of JQ1 on expression of autoimmune-related genes in CD4+T cells of systemic lupus erythematosus].
    Gao X; Gao K; Wu J; Zhao M
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2018 Jul; 43(7):704-710. PubMed ID: 30124204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement.
    Sengupta S; Biarnes MC; Clarke R; Jordan VC
    Breast Cancer Res Treat; 2015 Apr; 150(2):265-78. PubMed ID: 25721606
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury.
    Rudman MD; Choi JS; Lee HE; Tan SK; Ayad NG; Lee JK
    Exp Neurol; 2018 Nov; 309():181-192. PubMed ID: 30134146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
    Lenhart R; Kirov S; Desilva H; Cao J; Lei M; Johnston K; Peterson R; Schweizer L; Purandare A; Ross-Macdonald P; Fairchild C; Wong T; Wee S
    Mol Cancer Ther; 2015 Oct; 14(10):2167-74. PubMed ID: 26253517
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BET bromodomain inhibitor JQ1 decreases CD30 and CCR4 expression and proliferation of cutaneous T-cell lymphoma cell lines.
    Kamijo H; Sugaya M; Takahashi N; Oka T; Miyagaki T; Asano Y; Sato S
    Arch Dermatol Res; 2017 Aug; 309(6):491-497. PubMed ID: 28593508
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
    Leal AS; Williams CR; Royce DB; Pioli PA; Sporn MB; Liby KT
    Cancer Lett; 2017 May; 394():76-87. PubMed ID: 28254412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.
    Lee DU; Katavolos P; Palanisamy G; Katewa A; Sioson C; Corpuz J; Pang J; DeMent K; Choo E; Ghilardi N; Diaz D; Danilenko DM
    Toxicol Appl Pharmacol; 2016 Jun; 300():47-54. PubMed ID: 27078884
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
    Tögel L; Nightingale R; Chueh AC; Jayachandran A; Tran H; Phesse T; Wu R; Sieber OM; Arango D; Dhillon AS; Dawson MA; Diez-Dacal B; Gahman TC; Filippakopoulos P; Shiau AK; Mariadason JM
    Mol Cancer Ther; 2016 Jun; 15(6):1217-26. PubMed ID: 26983878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological Targeting of BET Bromodomains Inhibits Lens Fibrosis via Downregulation of MYC Expression.
    Wang X; Wang B; Zhao N; Wang C; Huang M; Chen B; Chen J; Sun Y; Xiong L; Huang S; Liu Y
    Invest Ophthalmol Vis Sci; 2019 Nov; 60(14):4748-4758. PubMed ID: 31731295
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma.
    Sengupta D; Kannan A; Kern M; Moreno MA; Vural E; Stack B; Suen JY; Tackett AJ; Gao L
    Epigenetics; 2015; 10(6):460-6. PubMed ID: 25941994
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage.
    Suarez-Alvarez B; Morgado-Pascual JL; Rayego-Mateos S; Rodriguez RM; Rodrigues-Diez R; Cannata-Ortiz P; Sanz AB; Egido J; Tharaux PL; Ortiz A; Lopez-Larrea C; Ruiz-Ortega M
    J Am Soc Nephrol; 2017 Feb; 28(2):504-519. PubMed ID: 27436852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer.
    Nagasawa M; Tomimatsu K; Terada K; Kondo K; Miyazaki K; Miyazaki M; Motooka D; Okuzaki D; Yoshida T; Kageyama S; Kawamoto H; Kawauchi A; Agata Y
    Biochem Biophys Res Commun; 2020 May; 526(1):128-134. PubMed ID: 32199616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.