These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 31312666)

  • 21. Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment.
    Villa-Bellosta R; Rivera-Torres J; Osorio FG; Acín-Pérez R; Enriquez JA; López-Otín C; Andrés V
    Circulation; 2013 Jun; 127(24):2442-51. PubMed ID: 23690466
    [TBL] [Abstract][Full Text] [Related]  

  • 22. mTORC1 signaling is essential for neurofibromatosis type I gene modulated osteogenic differentiation of BMSCs.
    Li Y; Li J; Zhou Q; Liu Y; Chen W; Xu H
    J Cell Biochem; 2019 Mar; 120(3):2886-2896. PubMed ID: 29266342
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts.
    Bikkul MU; Clements CS; Godwin LS; Goldberg MW; Kill IR; Bridger JM
    Biogerontology; 2018 Dec; 19(6):579-602. PubMed ID: 29907918
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J
    Med Hypotheses; 2018 Sep; 118():151-162. PubMed ID: 30037605
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.
    Osorio FG; Varela I; Lara E; Puente XS; Espada J; Santoro R; Freije JM; Fraga MF; López-Otín C
    Aging Cell; 2010 Dec; 9(6):947-57. PubMed ID: 20961378
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.
    Mallampalli MP; Huyer G; Bendale P; Gelb MH; Michaelis S
    Proc Natl Acad Sci U S A; 2005 Oct; 102(40):14416-21. PubMed ID: 16186497
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cell autonomous and systemic factors in progeria development.
    Osorio FG; Ugalde AP; Mariño G; Puente XS; Freije JM; López-Otín C
    Biochem Soc Trans; 2011 Dec; 39(6):1710-4. PubMed ID: 22103512
    [TBL] [Abstract][Full Text] [Related]  

  • 28. mTOR controls embryonic and adult myogenesis via mTORC1.
    Rion N; Castets P; Lin S; Enderle L; Reinhard JR; Eickhorst C; Rüegg MA
    Development; 2019 Apr; 146(7):. PubMed ID: 30872276
    [TBL] [Abstract][Full Text] [Related]  

  • 29. mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.
    Haller S; Kapuria S; Riley RR; O'Leary MN; Schreiber KH; Andersen JK; Melov S; Que J; Rando TA; Rock J; Kennedy BK; Rodgers JT; Jasper H
    Cell Stem Cell; 2017 Dec; 21(6):806-818.e5. PubMed ID: 29220665
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.
    Xie Y; Jin Y; Merenick BL; Ding M; Fetalvero KM; Wagner RJ; Mai A; Gleim S; Tucker DF; Birnbaum MJ; Ballif BA; Luciano AK; Sessa WC; Rzucidlo EM; Powell RJ; Hou L; Zhao H; Hwa J; Yu J; Martin KA
    Sci Signal; 2015 May; 8(376):ra44. PubMed ID: 25969542
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.
    Gabriel D; Gordon LB; Djabali K
    PLoS One; 2016; 11(12):e0168988. PubMed ID: 28033363
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Hutchinson-Gilford progeria syndrome as a model for vascular aging.
    Brassard JA; Fekete N; Garnier A; Hoesli CA
    Biogerontology; 2016 Feb; 17(1):129-45. PubMed ID: 26330290
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Genomic instability in laminopathy-based premature aging.
    Liu B; Wang J; Chan KM; Tjia WM; Deng W; Guan X; Huang JD; Li KM; Chau PY; Chen DJ; Pei D; Pendas AM; Cadiñanos J; López-Otín C; Tse HF; Hutchison C; Chen J; Cao Y; Cheah KS; Tryggvason K; Zhou Z
    Nat Med; 2005 Jul; 11(7):780-5. PubMed ID: 15980864
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mammalian Target of Rapamycin Complex 1 Signaling Is Required for the Dedifferentiation From Biliary Cell to Bipotential Progenitor Cell in Zebrafish Liver Regeneration.
    He J; Chen J; Wei X; Leng H; Mu H; Cai P; Luo L
    Hepatology; 2019 Dec; 70(6):2092-2106. PubMed ID: 31136010
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.
    Wu Z; Zhang W; Song M; Wang W; Wei G; Li W; Lei J; Huang Y; Sang Y; Chan P; Chen C; Qu J; Suzuki K; Belmonte JCI; Liu GH
    Protein Cell; 2018 Apr; 9(4):333-350. PubMed ID: 29476423
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Progeria of stem cells: stem cell exhaustion in Hutchinson-Gilford progeria syndrome.
    Halaschek-Wiener J; Brooks-Wilson A
    J Gerontol A Biol Sci Med Sci; 2007 Jan; 62(1):3-8. PubMed ID: 17301031
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation.
    Martin SK; Fitter S; Dutta AK; Matthews MP; Walkley CR; Hall MN; Ruegg MA; Gronthos S; Zannettino AC
    Stem Cells; 2015 Apr; 33(4):1359-65. PubMed ID: 25537496
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS.
    Denecke J; Brune T; Feldhaus T; Robenek H; Kranz C; Auchus RJ; Agarwal AK; Marquardt T
    Hum Mutat; 2006 Jun; 27(6):524-31. PubMed ID: 16671095
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Three-Dimensional Printed Titanium Scaffolds Enhance Osteogenic Differentiation and New Bone Formation by Cultured Adipose Tissue-Derived Stem Cells Through the IGF-1R/AKT/Mammalian Target of Rapamycin Complex 1 (mTORC1) Pathway.
    Zhou X; Zhang D; Wang M; Zhang D; Xu Y
    Med Sci Monit; 2019 Oct; 25():8043-8054. PubMed ID: 31655847
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis.
    Yalvac ME; Amornvit J; Braganza C; Chen L; Hussain SA; Shontz KM; Montgomery CL; Flanigan KM; Lewis S; Sahenk Z
    Skelet Muscle; 2017 Dec; 7(1):27. PubMed ID: 29241457
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.