BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 31313490)

  • 1. Hsp90β interacts with MDM2 to suppress p53-dependent senescence during skeletal muscle regeneration.
    He MY; Xu SB; Qu ZH; Guo YM; Liu XC; Cong XX; Wang JF; Low BC; Li L; Wu Q; Lin P; Yan SG; Bao Z; Zhou YT; Zheng LL
    Aging Cell; 2019 Oct; 18(5):e13003. PubMed ID: 31313490
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accumulation of Smooth Muscle 22α Protein Accelerates Senescence of Vascular Smooth Muscle Cells via Stabilization of p53 In Vitro and In Vivo.
    Miao SB; Xie XL; Yin YJ; Zhao LL; Zhang F; Shu YN; Chen R; Chen P; Dong LH; Lin YL; Lv P; Zhang DD; Nie X; Xue ZY; Han M
    Arterioscler Thromb Vasc Biol; 2017 Oct; 37(10):1849-1859. PubMed ID: 28798142
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
    Li D; Marchenko ND; Schulz R; Fischer V; Velasco-Hernandez T; Talos F; Moll UM
    Mol Cancer Res; 2011 May; 9(5):577-88. PubMed ID: 21478269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts.
    Oda T; Sekimoto T; Kurashima K; Fujimoto M; Nakai A; Yamashita T
    J Cell Sci; 2018 May; 131(9):. PubMed ID: 29632240
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tempo-spatial alternative polyadenylation analysis reveals that 3' UTR lengthening of Mdm2 regulates p53 expression and cellular senescence in aged rat testis.
    Wang L; Chen M; Fu H; Ni T; Wei G
    Biochem Biophys Res Commun; 2020 Mar; 523(4):1046-1052. PubMed ID: 31973811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MDM2 chaperones the p53 tumor suppressor.
    Wawrzynow B; Zylicz A; Wallace M; Hupp T; Zylicz M
    J Biol Chem; 2007 Nov; 282(45):32603-12. PubMed ID: 17848574
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner.
    Liu B; Yi J; Yang X; Liu L; Lou X; Zhang Z; Qi H; Wang Z; Zou J; Zhu WG; Gu W; Luo J
    Oncogene; 2019 Apr; 38(14):2501-2515. PubMed ID: 30532073
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
    Zheng ZG; Zhang X; Liu XX; Jin XX; Dai L; Cheng HM; Jing D; Thu PM; Zhang M; Li H; Zhu J; Liu C; Xue B; Li Y; Chen L; Peng C; Zhu W; Wang L; Liu J; Li HJ; Li P; Xu X
    Theranostics; 2019; 9(20):5769-5783. PubMed ID: 31534518
    [No Abstract]   [Full Text] [Related]  

  • 9. Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells.
    Lin K; Rockliffe N; Johnson GG; Sherrington PD; Pettitt AR
    Oncogene; 2008 Apr; 27(17):2445-55. PubMed ID: 17982489
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells.
    Cao LQ; Wang YN; Liang M; Pan MZ
    Mol Med Rep; 2019 Jun; 19(6):5097-5104. PubMed ID: 31059057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.
    Wei J; Yang Y; Lu M; Xu L; Liu F; Yuan Z; Bao Q; Jiang Z; Xu X; Guo X; Zhang X; You Q; Sun H
    Anticancer Agents Med Chem; 2015; 16(2):174-89. PubMed ID: 26343143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence.
    Xu X; Liu Q; Zhang C; Ren S; Xu L; Zhao Z; Dou H; Li P; Zhang X; Gong Y; Shao C
    Cell Death Dis; 2019 Mar; 10(4):282. PubMed ID: 30910997
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
    Zhang XW; Wang XF; Ni SJ; Qin W; Zhao LQ; Hua RX; Lu YW; Li J; Dimri GP; Guo WJ
    J Pathol; 2015 Mar; 235(4):656-67. PubMed ID: 25382750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer.
    Wu B; Chu X; Feng C; Hou J; Fan H; Liu N; Li C; Kong X; Ye X; Meng S
    Cancer Lett; 2015 Apr; 359(2):325-34. PubMed ID: 25637791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
    Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
    Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence.
    Volk EL; Schuster K; Nemeth KM; Fan L; Harris LC
    Dis Model Mech; 2009; 2(1-2):47-55. PubMed ID: 19132120
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.
    Walerych D; Gutkowska M; Klejman MP; Wawrzynow B; Tracz Z; Wiech M; Zylicz M; Zylicz A
    J Biol Chem; 2010 Oct; 285(42):32020-8. PubMed ID: 20688913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CHIP-dependent p53 regulation occurs specifically during cellular senescence.
    Sisoula C; Trachana V; Patterson C; Gonos ES
    Free Radic Biol Med; 2011 Jan; 50(1):157-65. PubMed ID: 20974249
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HSP90β chaperoning SMURF1-mediated LATS proteasomal degradation in the regulation of bone formation.
    Qu M; Gong Y; Jin Y; Gao R; He Q; Xu Y; Shen T; Mei L; Xu C; Hussain M; Barkat MQ; Wu X
    Cell Signal; 2023 Feb; 102():110523. PubMed ID: 36379376
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53.
    Fu JL; Zheng SY; Wang Y; Hu XB; Xiao Y; Wang JM; Zhang L; Wang L; Nie Q; Hou M; Bai YY; Gan YW; Liang XM; Xie LL; Li DW
    Proc Natl Acad Sci U S A; 2023 Aug; 120(31):e2221522120. PubMed ID: 37487085
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.