BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 31315662)

  • 1. Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels.
    Wang ZJ; Tiwari PB; Üren A; Brelidze TI
    BMC Pharmacol Toxicol; 2019 Jul; 20(1):42. PubMed ID: 31315662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity.
    Wang ZJ; Soohoo SM; Tiwari PB; Piszczek G; Brelidze TI
    J Biol Chem; 2020 Mar; 295(13):4114-4123. PubMed ID: 32047112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of PAS and CNBH domain interactions in hERG channels and effects of long-QT syndrome-causing mutations with surface plasmon resonance.
    Soohoo SM; Tiwari PB; Suzuki YJ; Brelidze TI
    J Biol Chem; 2022 Jan; 298(1):101433. PubMed ID: 34801551
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain.
    Kume S; Shimomura T; Tateyama M; Kubo Y
    J Physiol; 2018 Oct; 596(19):4629-4650. PubMed ID: 30086184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The structural mechanism of KCNH-channel regulation by the eag domain.
    Haitin Y; Carlson AE; Zagotta WN
    Nature; 2013 Sep; 501(7467):444-8. PubMed ID: 23975098
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains.
    Codding SJ; Johnson AA; Trudeau MC
    Channels (Austin); 2020 Dec; 14(1):294-309. PubMed ID: 32924766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The enigmatic cytoplasmic regions of KCNH channels.
    Morais-Cabral JH; Robertson GA
    J Mol Biol; 2015 Jan; 427(1):67-76. PubMed ID: 25158096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating.
    Harley CA; Bernardo-Seisdedos G; Stevens-Sostre WA; Jones DK; Azevedo MM; Sampaio P; Lorga-Gomes M; Trudeau MC; Millet O; Robertson GA; Morais-Cabral JH
    Proc Natl Acad Sci U S A; 2021 Nov; 118(44):. PubMed ID: 34716268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Screening for Non-Pore-Binding Modulators of EAG K+ Channels.
    Fernandes AS; Morais-Cabral JH; Harley CA
    J Biomol Screen; 2016 Aug; 21(7):758-65. PubMed ID: 26975997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural properties of PAS domains from the KCNH potassium channels.
    Adaixo R; Harley CA; Castro-Rodrigues AF; Morais-Cabral JH
    PLoS One; 2013; 8(3):e59265. PubMed ID: 23555008
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the carboxy-terminal region of a KCNH channel.
    Brelidze TI; Carlson AE; Sankaran B; Zagotta WN
    Nature; 2012 Jan; 481(7382):530-3. PubMed ID: 22230959
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular mechanism of EAG1 channel inhibition by imipramine binding to the PAS domain.
    Wang ZJ; Ghorbani M; Chen X; Tiwari PB; Klauda JB; Brelidze TI
    J Biol Chem; 2023 Dec; 299(12):105391. PubMed ID: 37898402
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of Surface Plasmon Resonance Technique for Studies of Inter-domain Interactions in Ion Channels.
    Tiwari PB; Kamgar-Dayhoff P; Tiwari P; McKillop MI; Brelidze TI
    Methods Mol Biol; 2024; 2796():105-118. PubMed ID: 38856898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ether-à-go-go K
    Bauer CK; Schwarz JR
    J Physiol; 2018 Mar; 596(5):769-783. PubMed ID: 29333676
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.
    Ng CA; Ke Y; Perry MD; Tan PS; Hill AP; Vandenberg JI
    PLoS One; 2013; 8(10):e77032. PubMed ID: 24204727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of the PAS domain of the hEAG potassium channel.
    Tang X; Shao J; Qin X
    Acta Crystallogr F Struct Biol Commun; 2016 Aug; 72(Pt 8):578-85. PubMed ID: 27487920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The subfamily-specific assembly of Eag and Erg K+ channels is determined by both the amino and the carboxyl recognition domains.
    Lin TF; Lin IW; Chen SC; Wu HH; Yang CS; Fang HY; Chiu MM; Jeng CJ
    J Biol Chem; 2014 Aug; 289(33):22815-22834. PubMed ID: 25008323
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chlorpromazine inhibits EAG1 channels by altering the coupling between the PAS, CNBH and pore domains.
    Ghorbani M; Wang ZJ; Chen X; Tiwari PB; Klauda JB; Brelidze TI
    bioRxiv; 2024 Feb; ():. PubMed ID: 38464246
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels.
    Garg V; Stary-Weinzinger A; Sanguinetti MC
    Mol Pharmacol; 2013 Apr; 83(4):805-13. PubMed ID: 23319419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional analysis of a mouse brain Elk-type K+ channel.
    Trudeau MC; Titus SA; Branchaw JL; Ganetzky B; Robertson GA
    J Neurosci; 1999 Apr; 19(8):2906-18. PubMed ID: 10191308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.