BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 31321400)

  • 1. Copper relay path through the N-terminus of Wilson disease protein, ATP7B.
    Shanmugavel KP; Wittung-Stafshede P
    Metallomics; 2019 Sep; 11(9):1472-1480. PubMed ID: 31321400
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing functional roles of Wilson disease protein (ATP7B) copper-binding domains in yeast.
    Ponnandai Shanmugavel K; Petranovic D; Wittung-Stafshede P
    Metallomics; 2017 Jul; 9(7):981-988. PubMed ID: 28653724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The six metal binding domains in human copper transporter, ATP7B: molecular biophysics and disease-causing mutations.
    Ariöz C; Li Y; Wittung-Stafshede P
    Biometals; 2017 Dec; 30(6):823-840. PubMed ID: 29063292
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics.
    Yu CH; Yang N; Bothe J; Tonelli M; Nokhrin S; Dolgova NV; Braiterman L; Lutsenko S; Dmitriev OY
    J Biol Chem; 2017 Nov; 292(44):18169-18177. PubMed ID: 28900031
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disease-causing point-mutations in metal-binding domains of Wilson disease protein decrease stability and increase structural dynamics.
    Kumar R; Ariöz C; Li Y; Bosaeus N; Rocha S; Wittung-Stafshede P
    Biometals; 2017 Feb; 30(1):27-35. PubMed ID: 27744583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pivotal role of MBD4-ATP7B in the human Cu(i) excretion path as revealed by EPR experiments and all-atom simulations.
    Qasem Z; Pavlin M; Ritacco I; Gevorkyan-Airapetov L; Magistrato A; Ruthstein S
    Metallomics; 2019 Jul; 11(7):1288-1297. PubMed ID: 31187846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Structure of Metal Binding Domain 1 of the Copper Transporter ATP7B Reveals Mechanism of a Singular Wilson Disease Mutation.
    Yu CH; Lee W; Nokhrin S; Dmitriev OY
    Sci Rep; 2018 Jan; 8(1):581. PubMed ID: 29330485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cu(I) binding and transfer by the N terminus of the Wilson disease protein.
    Yatsunyk LA; Rosenzweig AC
    J Biol Chem; 2007 Mar; 282(12):8622-31. PubMed ID: 17229731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In-silico analysis of novel p.(Gly14Ser) variant of ATOX1 gene: plausible role in modulating ATOX1-ATP7B interaction.
    Kumari N; Kumar A; Pal A; Thapa BR; Modi M; Prasad R
    Mol Biol Rep; 2019 Jun; 46(3):3307-3313. PubMed ID: 30980273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs.
    Lasorsa A; Nardella MI; Rosato A; Mirabelli V; Caliandro R; Caliandro R; Natile G; Arnesano F
    J Am Chem Soc; 2019 Jul; 141(30):12109-12120. PubMed ID: 31283225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human copper transporter ATP7B (Wilson disease protein) forms stable dimers
    Jayakanthan S; Braiterman LT; Hasan NM; Unger VM; Lutsenko S
    J Biol Chem; 2017 Nov; 292(46):18760-18774. PubMed ID: 28842499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions between copper-binding sites determine the redox status and conformation of the regulatory N-terminal domain of ATP7B.
    LeShane ES; Shinde U; Walker JM; Barry AN; Blackburn NJ; Ralle M; Lutsenko S
    J Biol Chem; 2010 Feb; 285(9):6327-36. PubMed ID: 20032459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational dynamics of metal-binding domains in Wilson disease protein: molecular insights into selective copper transfer.
    Rodriguez-Granillo A; Crespo A; Wittung-Stafshede P
    Biochemistry; 2009 Jun; 48(25):5849-63. PubMed ID: 19449859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Luminal Loop of Wilson Disease Protein Binds Copper and Is Required for Protein Activity.
    Köhn B; Ponnandai Shanmugavel K; Wu M; Kovermann M; Wittung-Stafshede P
    Biophys J; 2018 Sep; 115(6):1007-1018. PubMed ID: 30173886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P
    Maghool S; Fontaine S; Roberts BR; Kwan AH; Maher MJ
    Sci Rep; 2020 Mar; 10(1):4157. PubMed ID: 32139726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Copper transfer to the N-terminal domain of the Wilson disease protein (ATP7B): X-ray absorption spectroscopy of reconstituted and chaperone-loaded metal binding domains and their interaction with exogenous ligands.
    Ralle M; Lutsenko S; Blackburn NJ
    J Inorg Biochem; 2004 May; 98(5):765-74. PubMed ID: 15134922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity.
    Walker JM; Tsivkovskii R; Lutsenko S
    J Biol Chem; 2002 Aug; 277(31):27953-9. PubMed ID: 12029094
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An αB-Crystallin Peptide Rescues Compartmentalization and Trafficking Response to Cu Overload of ATP7B-H1069Q, the Most Frequent Cause of Wilson Disease in the Caucasian Population.
    Allocca S; Ciano M; Ciardulli MC; D'Ambrosio C; Scaloni A; Sarnataro D; Caporaso MG; D'Agostino M; Bonatti S
    Int J Mol Sci; 2018 Jun; 19(7):. PubMed ID: 29954118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Copper binding to the N-terminal metal-binding sites or the CPC motif is not essential for copper-induced trafficking of the human Wilson protein (ATP7B).
    Cater MA; La Fontaine S; Mercer JF
    Biochem J; 2007 Jan; 401(1):143-53. PubMed ID: 16939419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein.
    McCann CJ; Jayakanthan S; Siotto M; Yang N; Osipova M; Squitti R; Lutsenko S
    Metallomics; 2019 Jun; 11(6):1128-1139. PubMed ID: 31070637
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.