These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 31324451)

  • 1. Modeling Hypertrophic Cardiomyopathy: Mechanistic Insights and Pharmacological Intervention.
    Mosqueira D; Smith JGW; Bhagwan JR; Denning C
    Trends Mol Med; 2019 Sep; 25(9):775-790. PubMed ID: 31324451
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics.
    Bhagwan JR; Mosqueira D; Chairez-Cantu K; Mannhardt I; Bodbin SE; Bakar M; Smith JGW; Denning C
    J Mol Cell Cardiol; 2020 Aug; 145():43-53. PubMed ID: 32531470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy.
    Mosqueira D; Mannhardt I; Bhagwan JR; Lis-Slimak K; Katili P; Scott E; Hassan M; Prondzynski M; Harmer SC; Tinker A; Smith JGW; Carrier L; Williams PM; Gaffney D; Eschenhagen T; Hansen A; Denning C
    Eur Heart J; 2018 Nov; 39(43):3879-3892. PubMed ID: 29741611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Translational investigation of electrophysiology in hypertrophic cardiomyopathy.
    Flenner F; Jungen C; Küpker N; Ibel A; Kruse M; Koivumäki JT; Rinas A; Zech ATL; Rhoden A; Wijnker PJM; Lemoine MD; Steenpass A; Girdauskas E; Eschenhagen T; Meyer C; van der Velden J; Patten-Hamel M; Christ T; Carrier L
    J Mol Cell Cardiol; 2021 Aug; 157():77-89. PubMed ID: 33957110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy.
    Riaz M; Park J; Sewanan LR; Ren Y; Schwan J; Das SK; Pomianowski PT; Huang Y; Ellis MW; Luo J; Liu J; Song L; Chen IP; Qiu C; Yazawa M; Tellides G; Hwa J; Young LH; Yang L; Marboe CC; Jacoby DL; Campbell SG; Qyang Y
    Circulation; 2022 Apr; 145(16):1238-1253. PubMed ID: 35384713
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice.
    Flenner F; Geertz B; Reischmann-Düsener S; Weinberger F; Eschenhagen T; Carrier L; Friedrich FW
    J Physiol; 2017 Jun; 595(12):3987-3999. PubMed ID: 28090637
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome.
    Jaffré F; Miller CL; Schänzer A; Evans T; Roberts AE; Hahn A; Kontaridis MI
    Circulation; 2019 Jul; 140(3):207-224. PubMed ID: 31163979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Association Between Sarcomeric Variants in Hypertrophic Cardiomyopathy and Myocardial Oxygenation: Insights From a Novel Oxygen-Sensitive Cardiovascular Magnetic Resonance Approach.
    Raman B; Tunnicliffe EM; Chan K; Ariga R; Hundertmark M; Ohuma EO; Sivalokanathan S; Tan YJG; Mahmod M; Hess AT; Karamitsos TD; Selvanayagam J; Jerosch-Herold M; Watkins H; Neubauer S
    Circulation; 2021 Nov; 144(20):1656-1658. PubMed ID: 34780254
    [No Abstract]   [Full Text] [Related]  

  • 9. MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling.
    Li X; Lu WJ; Li Y; Wu F; Bai R; Ma S; Dong T; Zhang H; Lee AS; Wang Y; Lan F
    Cell Death Dis; 2019 Aug; 10(8):610. PubMed ID: 31406109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics.
    Tucholski T; Cai W; Gregorich ZR; Bayne EF; Mitchell SD; McIlwain SJ; de Lange WJ; Wrobbel M; Karp H; Hite Z; Vikhorev PG; Marston SB; Lal S; Li A; Dos Remedios C; Kohmoto T; Hermsen J; Ralphe JC; Kamp TJ; Moss RL; Ge Y
    Proc Natl Acad Sci U S A; 2020 Oct; 117(40):24691-24700. PubMed ID: 32968017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes.
    Tanaka A; Yuasa S; Mearini G; Egashira T; Seki T; Kodaira M; Kusumoto D; Kuroda Y; Okata S; Suzuki T; Inohara T; Arimura T; Makino S; Kimura K; Kimura A; Furukawa T; Carrier L; Node K; Fukuda K
    J Am Heart Assoc; 2014 Nov; 3(6):e001263. PubMed ID: 25389285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.
    Najafi A; Sequeira V; Helmes M; Bollen IA; Goebel M; Regan JA; Carrier L; Kuster DW; Van Der Velden J
    Cardiovasc Res; 2016 May; 110(2):200-14. PubMed ID: 26825555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.
    Yotti R; Seidman CE; Seidman JG
    Annu Rev Genomics Hum Genet; 2019 Aug; 20():129-153. PubMed ID: 30978303
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice.
    Chai AC; Cui M; Chemello F; Li H; Chen K; Tan W; Atmanli A; McAnally JR; Zhang Y; Xu L; Liu N; Bassel-Duby R; Olson EN
    Nat Med; 2023 Feb; 29(2):401-411. PubMed ID: 36797478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deficiency of Transcription Factor Sp1 Contributes to Hypertrophic Cardiomyopathy.
    Zhang F; Zhou H; Xue J; Zhang Y; Zhou L; Leng J; Fang G; Liu Y; Wang Y; Liu H; Wu Y; Qi L; Duan R; He X; Wang Y; Liu Y; Li L; Yang J; Liang D; Chen YH
    Circ Res; 2024 Feb; 134(3):290-306. PubMed ID: 38197258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes.
    Monteiro da Rocha A; Guerrero-Serna G; Helms A; Luzod C; Mironov S; Russell M; Jalife J; Day SM; Smith GD; Herron TJ
    J Mol Cell Cardiol; 2016 Oct; 99():197-206. PubMed ID: 27620334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy.
    O'Leary TS; Snyder J; Sadayappan S; Day SM; Previs MJ
    J Mol Cell Cardiol; 2019 Feb; 127():165-173. PubMed ID: 30550750
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
    Thottakara T; Friedrich FW; Reischmann S; Braumann S; Schlossarek S; Krämer E; Juhr D; Schlüter H; van der Velden J; Münch J; Patten M; Eschenhagen T; Moog-Lutz C; Carrier L
    J Mol Cell Cardiol; 2015 Oct; 87():214-24. PubMed ID: 26343497
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo.
    James V; Nizamudeen ZA; Lea D; Dottorini T; Holmes TL; Johnson BB; Arkill KP; Denning C; Smith JGW
    Stem Cells Dev; 2021 Dec; 30(24):1215-1227. PubMed ID: 34806414
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy.
    Ranjbarvaziri S; Kooiker KB; Ellenberger M; Fajardo G; Zhao M; Vander Roest AS; Woldeyes RA; Koyano TT; Fong R; Ma N; Tian L; Traber GM; Chan F; Perrino J; Reddy S; Chiu W; Wu JC; Woo JY; Ruppel KM; Spudich JA; Snyder MP; Contrepois K; Bernstein D
    Circulation; 2021 Nov; 144(21):1714-1731. PubMed ID: 34672721
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.