212 related articles for article (PubMed ID: 31330158)
1. Status update on iRhom and ADAM17: It's still complicated.
Düsterhöft S; Babendreyer A; Giese AA; Flasshove C; Ludwig A
Biochim Biophys Acta Mol Cell Res; 2019 Oct; 1866(10):1567-1583. PubMed ID: 31330158
[TBL] [Abstract][Full Text] [Related]
2. FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Künzel U; Grieve AG; Meng Y; Sieber B; Cowley SA; Freeman M
Elife; 2018 Jun; 7():. PubMed ID: 29897336
[TBL] [Abstract][Full Text] [Related]
3. The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Düsterhöft S; Kahveci-Türköz S; Wozniak J; Seifert A; Kasparek P; Ohm H; Liu S; Kopkanova J; Lokau J; Garbers C; Preisinger C; Sedlacek R; Freeman M; Ludwig A
Cell Mol Life Sci; 2021 Jun; 78(11):5015-5040. PubMed ID: 33950315
[TBL] [Abstract][Full Text] [Related]
4. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
[TBL] [Abstract][Full Text] [Related]
5. Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17.
Zhao Y; Dávila EM; Li X; Tang B; Rabinowitsch AI; Perez-Aguilar JM; Blobel CP
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361585
[TBL] [Abstract][Full Text] [Related]
6. iRhom2: An Emerging Adaptor Regulating Immunity and Disease.
Al-Salihi MA; Lang PA
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32911849
[TBL] [Abstract][Full Text] [Related]
7. A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Kahveci-Türköz S; Bläsius K; Wozniak J; Rinkens C; Seifert A; Kasparek P; Ohm H; Oltzen S; Nieszporek M; Schwarz N; Babendreyer A; Preisinger C; Sedlacek R; Ludwig A; Düsterhöft S
Cell Mol Life Sci; 2023 Apr; 80(5):135. PubMed ID: 37119365
[TBL] [Abstract][Full Text] [Related]
8. The molecular, cellular and pathophysiological roles of iRhom pseudoproteases.
Dulloo I; Muliyil S; Freeman M
Open Biol; 2019 Mar; 9(3):190003. PubMed ID: 30890028
[TBL] [Abstract][Full Text] [Related]
9. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Oikonomidi I; Burbridge E; Cavadas M; Sullivan G; Collis B; Naegele H; Clancy D; Brezinova J; Hu T; Bileck A; Gerner C; Bolado A; von Kriegsheim A; Martin SJ; Steinberg F; Strisovsky K; Adrain C
Elife; 2018 Jun; 7():. PubMed ID: 29897333
[TBL] [Abstract][Full Text] [Related]
10. Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells.
Babendreyer A; Rojas-González DM; Giese AA; Fellendorf S; Düsterhöft S; Mela P; Ludwig A
Front Cardiovasc Med; 2020; 7():610344. PubMed ID: 33335915
[No Abstract] [Full Text] [Related]
11. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Weskamp G; Tüshaus J; Li D; Feederle R; Maretzky T; Swendemann S; Falck-Pedersen E; McIlwain DR; Mak TW; Salmon JE; Lichtenthaler SF; Blobel CP
J Biol Chem; 2020 Mar; 295(13):4350-4358. PubMed ID: 32060096
[TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.
Grieve AG; Xu H; Künzel U; Bambrough P; Sieber B; Freeman M
Elife; 2017 Apr; 6():. PubMed ID: 28432785
[TBL] [Abstract][Full Text] [Related]
13. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
[TBL] [Abstract][Full Text] [Related]
14. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Maney SK; McIlwain DR; Polz R; Pandyra AA; Sundaram B; Wolff D; Ohishi K; Maretzky T; Brooke MA; Evers A; Vasudevan AA; Aghaeepour N; Scheller J; Münk C; Häussinger D; Mak TW; Nolan GP; Kelsell DP; Blobel CP; Lang KS; Lang PA
Sci Signal; 2015 Nov; 8(401):ra109. PubMed ID: 26535007
[TBL] [Abstract][Full Text] [Related]
15. Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.
Matthews AL; Noy PJ; Reyat JS; Tomlinson MG
Platelets; 2017 Jun; 28(4):333-341. PubMed ID: 27256961
[TBL] [Abstract][Full Text] [Related]
16. iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells.
Sieber B; Lu F; Stribbling SM; Grieve AG; Ryan AJ; Freeman M
J Cell Sci; 2022 Sep; 135(17):. PubMed ID: 35971826
[TBL] [Abstract][Full Text] [Related]
17. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
[TBL] [Abstract][Full Text] [Related]
18. Role of iRhoms 1 and 2 in Endochondral Ossification.
Fang R; Haxaire C; Otero M; Lessard S; Weskamp G; McIlwain DR; Mak TW; Lichtenthaler SF; Blobel CP
Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33227998
[TBL] [Abstract][Full Text] [Related]
19. iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I.
Calligaris M; Spanò DP; Bonelli S; Müller SA; Carcione C; D'apolito D; Amico G; Miele M; Di Bella M; Zito G; Nuti E; Rossello A; Blobel CP; Lichtenthaler SF; Scilabra SD
Cell Mol Life Sci; 2024 Apr; 81(1):163. PubMed ID: 38570362
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Cavadas M; Oikonomidi I; Gaspar CJ; Burbridge E; Badenes M; Félix I; Bolado A; Hu T; Bileck A; Gerner C; Domingos PM; von Kriegsheim A; Adrain C
Cell Rep; 2017 Oct; 21(3):745-757. PubMed ID: 29045841
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
