BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 31332069)

  • 1. 1
    Korycka-Machała M; Viljoen A; Pawełczyk J; Borówka P; Dziadek B; Gobis K; Brzostek A; Kawka M; Blaise M; Strapagiel D; Kremer L; Dziadek J
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31332069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
    Williams JT; Haiderer ER; Coulson GB; Conner KN; Ellsworth E; Chen C; Alvarez-Cabrera N; Li W; Jackson M; Dick T; Abramovitch RB
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31405862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.
    Tahlan K; Wilson R; Kastrinsky DB; Arora K; Nair V; Fischer E; Barnes SW; Walker JR; Alland D; Barry CE; Boshoff HI
    Antimicrob Agents Chemother; 2012 Apr; 56(4):1797-809. PubMed ID: 22252828
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A piperidinol-containing molecule is active against
    Dupont C; Chen Y; Xu Z; Roquet-Banères F; Blaise M; Witt AK; Dubar F; Biot C; Guérardel Y; Maurer FP; Chng SS; Kremer L
    J Biol Chem; 2019 Nov; 294(46):17512-17523. PubMed ID: 31562241
    [No Abstract]   [Full Text] [Related]  

  • 5. The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold.
    Ung KL; Alsarraf HMAB; Kremer L; Blaise M
    Proteins; 2020 Jun; 88(6):809-815. PubMed ID: 31833106
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active Benzimidazole Derivatives Targeting the MmpL3 Transporter in
    Raynaud C; Daher W; Johansen MD; Roquet-Banères F; Blaise M; Onajole OK; Kozikowski AP; Herrmann JL; Dziadek J; Gobis K; Kremer L
    ACS Infect Dis; 2020 Feb; 6(2):324-337. PubMed ID: 31860799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MmpL3 inhibitors as antituberculosis drugs.
    Shao M; McNeil M; Cook GM; Lu X
    Eur J Med Chem; 2020 Aug; 200():112390. PubMed ID: 32447196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.
    Grzegorzewicz AE; Pham H; Gundi VA; Scherman MS; North EJ; Hess T; Jones V; Gruppo V; Born SE; Korduláková J; Chavadi SS; Morisseau C; Lenaerts AJ; Lee RE; McNeil MR; Jackson M
    Nat Chem Biol; 2012 Feb; 8(4):334-41. PubMed ID: 22344175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter.
    Zheng H; Williams JT; Coulson GB; Haiderer ER; Abramovitch RB
    Antimicrob Agents Chemother; 2018 Jul; 62(7):. PubMed ID: 29661875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis.
    Li W; Upadhyay A; Fontes FL; North EJ; Wang Y; Crans DC; Grzegorzewicz AE; Jones V; Franzblau SG; Lee RE; Crick DC; Jackson M
    Antimicrob Agents Chemother; 2014 Nov; 58(11):6413-23. PubMed ID: 25136022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors.
    McNeil MB; O'Malley T; Dennison D; Shelton CD; Sunde B; Parish T
    mSphere; 2020 Oct; 5(5):. PubMed ID: 33055263
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.
    Li W; Obregón-Henao A; Wallach JB; North EJ; Lee RE; Gonzalez-Juarrero M; Schnappinger D; Jackson M
    Antimicrob Agents Chemother; 2016 Sep; 60(9):5198-207. PubMed ID: 27297488
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipid transport in Mycobacterium tuberculosis and its implications in virulence and drug development.
    Bailo R; Bhatt A; Aínsa JA
    Biochem Pharmacol; 2015 Aug; 96(3):159-67. PubMed ID: 25986884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acetylation of trehalose mycolates is required for efficient MmpL-mediated membrane transport in Corynebacterineae.
    Yamaryo-Botte Y; Rainczuk AK; Lea-Smith DJ; Brammananth R; van der Peet PL; Meikle P; Ralton JE; Rupasinghe TW; Williams SJ; Coppel RL; Crellin PK; McConville MJ
    ACS Chem Biol; 2015 Mar; 10(3):734-46. PubMed ID: 25427102
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis.
    Belardinelli JM; Yazidi A; Yang L; Fabre L; Li W; Jacques B; Angala SK; Rouiller I; Zgurskaya HI; Sygusch J; Jackson M
    ACS Infect Dis; 2016 Oct; 2(10):702-713. PubMed ID: 27737557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression.
    Degiacomi G; Benjak A; Madacki J; Boldrin F; Provvedi R; Palù G; Kordulakova J; Cole ST; Manganelli R
    Sci Rep; 2017 Feb; 7():43495. PubMed ID: 28240248
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria.
    Fay A; Czudnochowski N; Rock JM; Johnson JR; Krogan NJ; Rosenberg O; Glickman MS
    mBio; 2019 Jun; 10(3):. PubMed ID: 31239378
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting MmpL3 for anti-tuberculosis drug development.
    Bolla JR
    Biochem Soc Trans; 2020 Aug; 48(4):1463-1472. PubMed ID: 32662825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis.
    Umare MD; Khedekar PB; Chikhale RV
    ChemMedChem; 2021 Oct; 16(20):3136-3148. PubMed ID: 34288519
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.
    Su CC; Klenotic PA; Bolla JR; Purdy GE; Robinson CV; Yu EW
    Proc Natl Acad Sci U S A; 2019 Jun; 116(23):11241-11246. PubMed ID: 31113875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.