These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
206 related articles for article (PubMed ID: 31337753)
1. Evolution of metazoan oxygen-sensing involved a conserved divergence of VHL affinity for HIF1α and HIF2α. Tarade D; Lee JE; Ohh M Nat Commun; 2019 Jul; 10(1):3293. PubMed ID: 31337753 [TBL] [Abstract][Full Text] [Related]
3. Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex. Dong X; Su X; Yu J; Liu J; Shi X; Pan Q; Yang J; Chen J; Li L; Cao H J Mol Graph Model; 2017 Jan; 71():116-123. PubMed ID: 27902963 [TBL] [Abstract][Full Text] [Related]
4. Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α. Schönenberger D; Harlander S; Rajski M; Jacobs RA; Lundby AK; Adlesic M; Hejhal T; Wild PJ; Lundby C; Frew IJ Cancer Res; 2016 Apr; 76(7):2025-36. PubMed ID: 26759234 [TBL] [Abstract][Full Text] [Related]
5. Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes. Hicks KC; Patel TB J Biol Chem; 2016 Aug; 291(32):16787-801. PubMed ID: 27281823 [TBL] [Abstract][Full Text] [Related]
6. Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner. Todd VM; Vecchi LA; Clements ME; Snow KP; Ontko CD; Himmel L; Pinelli C; Rafat M; Johnson RW Commun Biol; 2021 Sep; 4(1):1122. PubMed ID: 34556788 [TBL] [Abstract][Full Text] [Related]
7. Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma. Ordóñez-Navadijo Á; Fuertes-Yebra E; Acosta-Iborra B; Balsa E; Elorza A; Aragonés J; Landazuri MO Oncogene; 2016 Feb; 35(5):587-94. PubMed ID: 25915846 [TBL] [Abstract][Full Text] [Related]
8. Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity. Bouthelier A; Meléndez-Rodríguez F; Urrutia AA; Aragonés J Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33321829 [TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Rathmell WK; Hickey MM; Bezman NA; Chmielecki CA; Carraway NC; Simon MC Cancer Res; 2004 Dec; 64(23):8595-603. PubMed ID: 15574766 [TBL] [Abstract][Full Text] [Related]
10. HIF alpha expression in VHL-deficient renal cancer cells is dependent on phospholipase D. Toschi A; Edelstein J; Rockwell P; Ohh M; Foster DA Oncogene; 2008 Apr; 27(19):2746-53. PubMed ID: 17998935 [TBL] [Abstract][Full Text] [Related]
11. Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo. Kim WY; Safran M; Buckley MR; Ebert BL; Glickman J; Bosenberg M; Regan M; Kaelin WG EMBO J; 2006 Oct; 25(19):4650-62. PubMed ID: 16977322 [TBL] [Abstract][Full Text] [Related]
12. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720 [TBL] [Abstract][Full Text] [Related]
13. Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas enhances HIF2α activity. Mathew LK; Lee SS; Skuli N; Rao S; Keith B; Nathanson KL; Lal P; Simon MC Cancer Discov; 2014 Jan; 4(1):53-60. PubMed ID: 24189146 [TBL] [Abstract][Full Text] [Related]
14. Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL). Heir P; Ohh M Methods Mol Biol; 2016; 1458():87-94. PubMed ID: 27581016 [TBL] [Abstract][Full Text] [Related]
15. The HIF and other quandaries in VHL disease. Tarade D; Ohh M Oncogene; 2018 Jan; 37(2):139-147. PubMed ID: 28925400 [TBL] [Abstract][Full Text] [Related]
16. Genotype-phenotype analysis of von Hippel-Lindau syndrome in Korean families: HIF-α binding site missense mutations elevate age-specific risk for CNS hemangioblastoma. Lee JS; Lee JH; Lee KE; Kim JH; Hong JM; Ra EK; Seo SH; Lee SJ; Kim MJ; Park SS; Seong MW BMC Med Genet; 2016 Jul; 17(1):48. PubMed ID: 27439424 [TBL] [Abstract][Full Text] [Related]
17. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma. Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795 [TBL] [Abstract][Full Text] [Related]
18. REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. Singh A; Cheng D; Swaminathan J; Yang Y; Zheng Y; Gordon N; Gopalakrishnan V Sci Rep; 2024 Jun; 14(1):13596. PubMed ID: 38866867 [TBL] [Abstract][Full Text] [Related]
19. Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma. Luu VD; Boysen G; Struckmann K; Casagrande S; von Teichman A; Wild PJ; Sulser T; Schraml P; Moch H Clin Cancer Res; 2009 May; 15(10):3297-304. PubMed ID: 19401348 [TBL] [Abstract][Full Text] [Related]
20. Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage. Stuart S; Tarade D; Ohh M Sci Rep; 2024 Jun; 14(1):14799. PubMed ID: 38926538 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]