These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
182 related articles for article (PubMed ID: 31340431)
1. Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2- Cawrse BM; Robinson NM; Lee NC; Wilson GM; Seley-Radtke KL Molecules; 2019 Jul; 24(14):. PubMed ID: 31340431 [TBL] [Abstract][Full Text] [Related]
2. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line. Jung MH; Kim H; Choi WK; El-Gamal MI; Park JH; Yoo KH; Sim TB; Lee SH; Baek D; Hah JM; Cho JH; Oh CH Bioorg Med Chem Lett; 2009 Dec; 19(23):6538-43. PubMed ID: 19857963 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors. Lee JH; Shin SC; Seo SH; Seo YH; Jeong N; Kim CW; Kim EE; Keum G Bioorg Med Chem Lett; 2017 Jan; 27(2):237-241. PubMed ID: 27914802 [TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of 2,6,7-substituted pyrrolo[2,3-d]pyrimidines as cyclin dependent kinase inhibitor in pancreatic cancer cells. Shi X; Quan Y; Wang Y; Wang Y; Li Y Bioorg Med Chem Lett; 2021 Feb; 33():127725. PubMed ID: 33316409 [TBL] [Abstract][Full Text] [Related]
6. Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution. Cawrse BM; Lapidus RS; Cooper B; Choi EY; Seley-Radtke KL ChemMedChem; 2018 Jan; 13(2):178-185. PubMed ID: 29193845 [TBL] [Abstract][Full Text] [Related]
7. Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidines as potential nonclassical antifolates targeting both thymidylate and purine nucleotide biosynthesis. Liu Y; Zhang C; Zhang H; Li M; Yuan J; Zhang Y; Zhou J; Guo H; Zhao L; Du Y; Wang L; Ren L Eur J Med Chem; 2015 Mar; 93():142-55. PubMed ID: 25668494 [TBL] [Abstract][Full Text] [Related]
8. Targeting dihydrofolate reductase: Design, synthesis and biological evaluation of novel 6-substituted pyrrolo[2,3-d]pyrimidines as nonclassical antifolates and as potential antitumor agents. Gao T; Zhang C; Shi X; Guo R; Zhang K; Gu J; Li L; Li S; Zheng Q; Cui M; Cui M; Gao X; Liu Y; Wang L Eur J Med Chem; 2019 Sep; 178():329-340. PubMed ID: 31200235 [TBL] [Abstract][Full Text] [Related]
10. Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase. Xing R; Zhang H; Yuan J; Zhang K; Li L; Guo H; Zhao L; Zhang C; Li S; Gao T; Liu Y; Wang L Eur J Med Chem; 2017 Oct; 139():531-541. PubMed ID: 28830032 [TBL] [Abstract][Full Text] [Related]
11. Synthesis of novel pyrrole and pyrrolo[2,3-d]pyrimidine derivatives bearing sulfonamide moiety for evaluation as anticancer and radiosensitizing agents. Ghorab MM; Ragab FA; Heiba HI; Youssef HA; El-Gazzar MG Bioorg Med Chem Lett; 2010 Nov; 20(21):6316-20. PubMed ID: 20850308 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides. Pudziuvelyte E; Ríos-Luci C; León LG; Cikotiene I; Padrón JM Bioorg Med Chem; 2009 Jul; 17(14):4955-60. PubMed ID: 19527934 [TBL] [Abstract][Full Text] [Related]
13. Novel 5,6-disubstituted pyrrolo[2,3-d]pyrimidine derivatives as broad spectrum antiproliferative agents: Synthesis, cell based assays, kinase profile and molecular docking study. Lee JH; El-Damasy AK; Seo SH; Gadhe CG; Pae AN; Jeong N; Hong SS; Keum G Bioorg Med Chem; 2018 Nov; 26(21):5596-5611. PubMed ID: 30385226 [TBL] [Abstract][Full Text] [Related]
14. 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance. Gangjee A; Namjoshi OA; Keller SN; Smith CD Bioorg Med Chem; 2011 Jul; 19(14):4355-65. PubMed ID: 21680190 [TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of novel 6-substituted pyrrolo [3,2-d] pyrimidine analogues as antifolate antitumor agents. Tian C; Wang M; Han Z; Fang F; Zhang Z; Wang X; Liu J Eur J Med Chem; 2017 Sep; 138():630-643. PubMed ID: 28711701 [TBL] [Abstract][Full Text] [Related]
16. Diarylureas and diarylamides with pyrrolo[2,3-d]pyrimidine scaffold as broad-spectrum anticancer agents. El-Gamal MI; Oh CH Chem Pharm Bull (Tokyo); 2014; 62(1):25-34. PubMed ID: 24390490 [TBL] [Abstract][Full Text] [Related]
17. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines. Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023 [TBL] [Abstract][Full Text] [Related]
18. Synthesis and evaluation of novel 7 Liu YM; Chen CH; Yeh TK; Liou JP Future Med Chem; 2019 May; 11(9):959-974. PubMed ID: 30789758 [No Abstract] [Full Text] [Related]
19. Synthesis, antiproliferative, and antiviral activity of certain 4-substituted and 4,5-disubstituted 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3-d]pyrimidines. Pudlo JS; Nassiri MR; Kern ER; Wotring LL; Drach JC; Townsend LB J Med Chem; 1990 Jul; 33(7):1984-92. PubMed ID: 2163454 [TBL] [Abstract][Full Text] [Related]
20. The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: a new class of Aurora-A kinase inhibitors. Moriarty KJ; Koblish HK; Garrabrant T; Maisuria J; Khalil E; Ali F; Petrounia IP; Crysler CS; Maroney AC; Johnson DL; Galemmo RA Bioorg Med Chem Lett; 2006 Nov; 16(22):5778-83. PubMed ID: 16949284 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]