239 related articles for article (PubMed ID: 31341022)
21. Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase).
Ilinskaya ON; Singh I; Dudkina E; Ulyanova V; Kayumov A; Barreto G
Biochim Biophys Acta; 2016 Jul; 1863(7 Pt A):1559-67. PubMed ID: 27066977
[TBL] [Abstract][Full Text] [Related]
22. Regulators and effectors of ras proteins.
Bollag G; McCormick F
Annu Rev Cell Biol; 1991; 7():601-32. PubMed ID: 1667084
[No Abstract] [Full Text] [Related]
23. Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.
Evelyn CR; Biesiada J; Duan X; Tang H; Shang X; Papoian R; Seibel WL; Nelson S; Meller J; Zheng Y
J Biol Chem; 2015 May; 290(20):12879-98. PubMed ID: 25825487
[TBL] [Abstract][Full Text] [Related]
24. Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation.
Heo J; Prutzman KC; Mocanu V; Campbell SL
J Mol Biol; 2005 Mar; 346(5):1423-40. PubMed ID: 15713491
[TBL] [Abstract][Full Text] [Related]
25. Control of ras activation.
Downward J
Cancer Surv; 1996; 27():87-100. PubMed ID: 8909796
[TBL] [Abstract][Full Text] [Related]
26. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching.
Goldberg J
Cell; 1998 Oct; 95(2):237-48. PubMed ID: 9790530
[TBL] [Abstract][Full Text] [Related]
27. Guanine nucleotide exchange factors: activators of Ras superfamily proteins.
Overbeck AF; Brtva TR; Cox AD; Graham SM; Huff SY; Khosravi-Far R; Quilliam LA; Solski PA; Der CJ
Mol Reprod Dev; 1995 Dec; 42(4):468-76. PubMed ID: 8607978
[TBL] [Abstract][Full Text] [Related]
28. Tissue-Specific Oncogenic Activity of KRAS
Poulin EJ; Bera AK; Lu J; Lin YJ; Strasser SD; Paulo JA; Huang TQ; Morales C; Yan W; Cook J; Nowak JA; Brubaker DK; Joughin BA; Johnson CW; DeStefanis RA; Ghazi PC; Gondi S; Wales TE; Iacob RE; Bogdanova L; Gierut JJ; Li Y; Engen JR; Perez-Mancera PA; Braun BS; Gygi SP; Lauffenburger DA; Westover KD; Haigis KM
Cancer Discov; 2019 Jun; 9(6):738-755. PubMed ID: 30952657
[No Abstract] [Full Text] [Related]
29. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
Tong LA; de Vos AM; Milburn MV; Kim SH
J Mol Biol; 1991 Feb; 217(3):503-16. PubMed ID: 1899707
[TBL] [Abstract][Full Text] [Related]
30. Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues.
Fujita-Yoshigaki J; Ito Y; Yamasaki K; Muto Y; Miyazawa T; Nishimura S; Yokoyama S
J Protein Chem; 1992 Dec; 11(6):731-9. PubMed ID: 1466766
[TBL] [Abstract][Full Text] [Related]
31. Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.
Hodges TR; Abbott JR; Little AJ; Sarkar D; Salovich JM; Howes JE; Akan DT; Sai J; Arnold AL; Browning C; Burns MC; Sobolik T; Sun Q; Beesetty Y; Coker JA; Scharn D; Stadtmueller H; Rossanese OW; Phan J; Waterson AG; McConnell DB; Fesik SW
J Med Chem; 2018 Oct; 61(19):8875-8894. PubMed ID: 30205005
[TBL] [Abstract][Full Text] [Related]
32. Targeting Son of Sevenless 1: The pacemaker of KRAS.
Kessler D; Gerlach D; Kraut N; McConnell DB
Curr Opin Chem Biol; 2021 Jun; 62():109-118. PubMed ID: 33848766
[TBL] [Abstract][Full Text] [Related]
33. Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42.
Kintscher C; Groemping Y
J Mol Biol; 2009 Mar; 387(2):270-83. PubMed ID: 19356586
[TBL] [Abstract][Full Text] [Related]
34. Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly R; Gao G; Tesmer JJ
J Biol Chem; 2004 Nov; 279(45):47352-62. PubMed ID: 15331592
[TBL] [Abstract][Full Text] [Related]
35. Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation.
Mott HR; Carpenter JW; Campbell SL
Biochemistry; 1997 Mar; 36(12):3640-4. PubMed ID: 9132016
[TBL] [Abstract][Full Text] [Related]
36. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence.
Nomanbhoy TK; Leonard DA; Manor D; Cerione RA
Biochemistry; 1996 Apr; 35(14):4602-8. PubMed ID: 8605211
[TBL] [Abstract][Full Text] [Related]
37. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.
Nimnual AS; Yatsula BA; Bar-Sagi D
Science; 1998 Jan; 279(5350):560-3. PubMed ID: 9438849
[TBL] [Abstract][Full Text] [Related]
38. Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.
Quilliam LA; Huff SY; Rabun KM; Wei W; Park W; Broek D; Der CJ
Proc Natl Acad Sci U S A; 1994 Aug; 91(18):8512-6. PubMed ID: 8078913
[TBL] [Abstract][Full Text] [Related]
39. A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman TS; Sondermann H; Friedland GD; Kortemme T; Bar-Sagi D; Marqusee S; Kuriyan J
Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16692-7. PubMed ID: 17075039
[TBL] [Abstract][Full Text] [Related]
40. Structural basis for conformational dynamics of GTP-bound Ras protein.
Shima F; Ijiri Y; Muraoka S; Liao J; Ye M; Araki M; Matsumoto K; Yamamoto N; Sugimoto T; Yoshikawa Y; Kumasaka T; Yamamoto M; Tamura A; Kataoka T
J Biol Chem; 2010 Jul; 285(29):22696-705. PubMed ID: 20479006
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
