262 related articles for article (PubMed ID: 31342134)
1. Engineered antibodies: new possibilities for brain PET?
Sehlin D; Syvänen S;
Eur J Nucl Med Mol Imaging; 2019 Dec; 46(13):2848-2858. PubMed ID: 31342134
[TBL] [Abstract][Full Text] [Related]
2. A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging.
Syvänen S; Fang XT; Hultqvist G; Meier SR; Lannfelt L; Sehlin D
Neuroimage; 2017 Mar; 148():55-63. PubMed ID: 28069541
[TBL] [Abstract][Full Text] [Related]
3. High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain.
Fang XT; Hultqvist G; Meier SR; Antoni G; Sehlin D; Syvänen S
Neuroimage; 2019 Jan; 184():881-888. PubMed ID: 30300753
[TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β.
Sehlin D; Fang XT; Meier SR; Jansson M; Syvänen S
Sci Rep; 2017 Dec; 7(1):17254. PubMed ID: 29222502
[TBL] [Abstract][Full Text] [Related]
5. Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease.
Sehlin D; Fang XT; Cato L; Antoni G; Lannfelt L; Syvänen S
Nat Commun; 2016 Feb; 7():10759. PubMed ID: 26892305
[TBL] [Abstract][Full Text] [Related]
6. Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease.
Meier SR; Sehlin D; Hultqvist G; Syvänen S
Mol Imaging Biol; 2021 Oct; 23(5):665-675. PubMed ID: 33620643
[TBL] [Abstract][Full Text] [Related]
7. Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody.
Schlein E; Andersson KG; Dallas T; Syvänen S; Sehlin D
MAbs; 2024; 16(1):2339337. PubMed ID: 38634473
[TBL] [Abstract][Full Text] [Related]
8. ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein.
Bonvicini G; Syvänen S; Andersson KG; Haaparanta-Solin M; López-Picón F; Sehlin D
Transl Neurodegener; 2022 Dec; 11(1):55. PubMed ID: 36567338
[TBL] [Abstract][Full Text] [Related]
9. Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain.
Syvänen S; Fang XT; Faresjö R; Rokka J; Lannfelt L; Olberg DE; Eriksson J; Sehlin D
ACS Chem Neurosci; 2020 Dec; 11(24):4460-4468. PubMed ID: 33236886
[TBL] [Abstract][Full Text] [Related]
10. Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration.
Karaoglu Hanzatian D; Schwartz A; Gizatullin F; Erickson J; Deng K; Villanueva R; Stedman C; Harris C; Ghayur T; Goodearl A
MAbs; 2018 Jul; 10(5):765-777. PubMed ID: 29771629
[TBL] [Abstract][Full Text] [Related]
11. Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.
Syvänen S; Hultqvist G; Gustavsson T; Gumucio A; Laudon H; Söderberg L; Ingelsson M; Lannfelt L; Sehlin D
Alzheimers Res Ther; 2018 May; 10(1):49. PubMed ID: 29793530
[TBL] [Abstract][Full Text] [Related]
12. In vivo imaging of alpha-synuclein with antibody-based PET.
Roshanbin S; Xiong M; Hultqvist G; Söderberg L; Zachrisson O; Meier S; Ekmark-Lewén S; Bergström J; Ingelsson M; Sehlin D; Syvänen S
Neuropharmacology; 2022 May; 208():108985. PubMed ID: 35149134
[TBL] [Abstract][Full Text] [Related]
13. Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging.
Schlein E; Syvänen S; Rokka J; Gustavsson T; Rossin R; Robillard M; Eriksson J; Sehlin D
Mol Pharm; 2022 Nov; 19(11):4111-4122. PubMed ID: 36201682
[TBL] [Abstract][Full Text] [Related]
14. Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.
Yu YJ; Zhang Y; Kenrick M; Hoyte K; Luk W; Lu Y; Atwal J; Elliott JM; Prabhu S; Watts RJ; Dennis MS
Sci Transl Med; 2011 May; 3(84):84ra44. PubMed ID: 21613623
[TBL] [Abstract][Full Text] [Related]
15. Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor.
Hultqvist G; Syvänen S; Fang XT; Lannfelt L; Sehlin D
Theranostics; 2017; 7(2):308-318. PubMed ID: 28042336
[TBL] [Abstract][Full Text] [Related]
16. Development of brain-penetrable antibody radioligands for
Banka V; Kelleher A; Sehlin D; Hultqvist G; Sigurdsson EM; Syvänen S; Ding YS
Front Nucl Med; 2023; 3():. PubMed ID: 37680310
[TBL] [Abstract][Full Text] [Related]
17. Brain penetration, target engagement, and disposition of the blood-brain barrier-crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1.
Webster CI; Caram-Salas N; Haqqani AS; Thom G; Brown L; Rennie K; Yogi A; Costain W; Brunette E; Stanimirovic DB
FASEB J; 2016 May; 30(5):1927-40. PubMed ID: 26839377
[TBL] [Abstract][Full Text] [Related]
18. Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody.
Faresjö R; Sehlin D; Syvänen S
Fluids Barriers CNS; 2023 May; 20(1):34. PubMed ID: 37170266
[TBL] [Abstract][Full Text] [Related]
19. Re-engineering therapeutic antibodies for Alzheimer's disease as blood-brain barrier penetrating bi-specific antibodies.
Pardridge WM
Expert Opin Biol Ther; 2016 Dec; 16(12):1455-1468. PubMed ID: 27572805
[TBL] [Abstract][Full Text] [Related]
20. Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Rotman M; Welling MM; van den Boogaard ML; Moursel LG; van der Graaf LM; van Buchem MA; van der Maarel SM; van der Weerd L
Nucl Med Biol; 2015 Aug; 42(8):695-702. PubMed ID: 25960433
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
