These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 31343754)

  • 1. Anticancer activity of newly synthesized 1,1-disubstituted cyclohexane-1-carboxamides: in vitro caspases mediated apoptosis activators in human cancer cell lines and their molecular modeling.
    Abd-Allah WH; Salman A; Sabry Saad S
    Drug Dev Res; 2019 Nov; 80(7):933-947. PubMed ID: 31343754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers.
    Nowar RM; A Osman EE; Abou-Seri SM; El Moghazy SM; Abou El Ella DA
    Future Med Chem; 2018 May; 10(10):1191-1205. PubMed ID: 29749767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents.
    Hisham M; Youssif BGM; Osman EEA; Hayallah AM; Abdel-Aziz M
    Eur J Med Chem; 2019 Aug; 176():117-128. PubMed ID: 31108261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
    Ibrahim TS; Hawwas MM; Taher ES; Alhakamy NA; Alfaleh MA; Elagawany M; Elgendy B; Zayed GM; Mohamed MFA; Abdel-Samii ZK; Elshaier YAMM
    Bioorg Chem; 2020 Dec; 105():104352. PubMed ID: 33080494
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents.
    Al-Mahmoudy A; Hassan A; Ibrahim T; Youssif BGM; Taher E; Tantawy M; Abdel-Aal E; Osman N
    Anticancer Agents Med Chem; 2022; 22(5):978-990. PubMed ID: 34126912
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A flavonoid isolated from Streptomyces sp. (ERINLG-4) induces apoptosis in human lung cancer A549 cells through p53 and cytochrome c release caspase dependant pathway.
    Balachandran C; Sangeetha B; Duraipandiyan V; Raj MK; Ignacimuthu S; Al-Dhabi NA; Balakrishna K; Parthasarathy K; Arulmozhi NM; Arasu MV
    Chem Biol Interact; 2014 Dec; 224():24-35. PubMed ID: 25289772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
    Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.
    Mourad AAE; Farouk NA; El-Sayed EH; Mahdy ARE
    Life Sci; 2021 Jul; 277():119531. PubMed ID: 33887348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New pyranopyrazole based derivatives: Design, synthesis, and biological evaluation as potential topoisomerase II inhibitors, apoptotic inducers, and antiproliferative agents.
    Sobh EA; Kassab AE; El-Khouly EA; S A Hassan M
    Bioorg Chem; 2024 Mar; 144():107158. PubMed ID: 38301427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of apoptosis by pyrazolo[3,4-d]pyridazine derivative in lung cancer cells via disruption of Bcl-2/Bax expression balance.
    Mohamed MS; Abdelhamid AO; Almutairi FM; Ali AG; Bishr MK
    Bioorg Med Chem; 2018 Feb; 26(3):623-629. PubMed ID: 29290491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, bioactivity assessment, molecular docking and ADMET studies of new chromone congeners exhibiting potent anticancer activity.
    Abo-Salem HM; El Souda SSM; Shafey HI; Zoheir KMA; Ahmed KM; Mahmoud K; Mahrous KF; Fawzy NM
    Sci Rep; 2024 Apr; 14(1):9636. PubMed ID: 38671055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of caspases, Bax and Bcl-2 in chrysin-induced apoptosis in the A549 human lung adenocarcinoma epithelial cells.
    Samarghandian S; Nezhad MA; Mohammadi G
    Anticancer Agents Med Chem; 2014; 14(6):901-9. PubMed ID: 24521149
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
    Elgiushy HR; Mohamed SH; Taha H; Sawaf H; Hassan Z; Abou-Taleb NA; El-Labbad EM; Hassan AS; Abouzid KAM; Hammad SF
    Bioorg Chem; 2022 Mar; 120():105646. PubMed ID: 35134645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
    Mohamed MF; Hassaneen HM; Abdelhamid IA
    Eur J Med Chem; 2018 Jan; 143():532-541. PubMed ID: 29207336
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators.
    Salah Ayoup M; Wahby Y; Abdel-Hamid H; Ramadan ES; Teleb M; Abu-Serie MM; Noby A
    Eur J Med Chem; 2019 Apr; 168():340-356. PubMed ID: 30826510
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation.
    Zhang J; Wang X; Yang J; Guo L; Wang X; Song B; Dong W; Wang W
    Eur J Med Chem; 2020 Jan; 186():111897. PubMed ID: 31761382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation.
    Warda ET; Shehata IA; El-Ashmawy MB; El-Gohary NS
    Bioorg Med Chem; 2020 Nov; 28(21):115674. PubMed ID: 33065442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase pathways.
    Nieves-Neira W; Pommier Y
    Int J Cancer; 1999 Jul; 82(3):396-404. PubMed ID: 10399957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents.
    Youssif BGM; Mohamed AM; Osman EEA; Abou-Ghadir OF; Elnaggar DH; Abdelrahman MH; Treamblu L; Gomaa HAM
    Eur J Med Chem; 2019 Sep; 177():1-11. PubMed ID: 31128433
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.