These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 31362457)

  • 1. Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.
    Aitken L; Benek O; McKelvie BE; Hughes RE; Hroch L; Schmidt M; Major LL; Vinklarova L; Kuca K; Smith TK; Musilek K; Gunn-Moore FJ
    Molecules; 2019 Jul; 24(15):. PubMed ID: 31362457
    [No Abstract]   [Full Text] [Related]  

  • 2. Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
    Hroch L; Benek O; Guest P; Aitken L; Soukup O; Janockova J; Musil K; Dohnal V; Dolezal R; Kuca K; Smith TK; Gunn-Moore F; Musilek K
    Bioorg Med Chem Lett; 2016 Aug; 26(15):3675-8. PubMed ID: 27287370
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.
    Hroch L; Guest P; Benek O; Soukup O; Janockova J; Dolezal R; Kuca K; Aitken L; Smith TK; Gunn-Moore F; Zala D; Ramsay RR; Musilek K
    Bioorg Med Chem; 2017 Feb; 25(3):1143-1152. PubMed ID: 28082069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.
    Schmidt M; Benek O; Vinklarova L; Hrabinova M; Zemanova L; Chribek M; Kralova V; Hroch L; Dolezal R; Lycka A; Prchal L; Jun D; Aitken L; Gunn-Moore F; Kuca K; Musilek K
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32192199
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.
    Benek O; Hroch L; Aitken L; Dolezal R; Guest P; Benkova M; Soukup O; Musil K; Kuca K; Smith TK; Gunn-Moore F; Musilek K
    Med Chem; 2017 Jan; ():. PubMed ID: 28067167
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-Hydroxyacyl-CoA and Alcohol Dehydrogenase Activities of Mitochondrial Type 10 17β-Hydroxysteroid Dehydrogenase in Neurodegeneration Study.
    He XY; Dobkin C; Brown WT; Yang SY
    J Alzheimers Dis; 2022; 88(4):1487-1497. PubMed ID: 35786658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of Type 10 17β-Hydroxysteroid Dehydrogenase in the Pathogenesis of Infantile Neurodegeneration and Alzheimer's Disease.
    He XY; Frackowiak J; Dobkin C; Brown WT; Yang SY
    Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139430
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
    Benek O; Vaskova M; Miskerikova M; Schmidt M; Andrys R; Rotterova A; Skarka A; Hatlapatkova J; Karasova JZ; Medvecky M; Hroch L; Vinklarova L; Fisar Z; Hroudova J; Handl J; Capek J; Rousar T; Kobrlova T; Dolezal R; Soukup O; Aitken L; Gunn-Moore F; Musilek K
    Eur J Med Chem; 2023 Oct; 258():115593. PubMed ID: 37390508
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Infantile Neurodegeneration Results from Mutants of 17β-Hydroxysteroid Dehydrogenase Type 10 Rather Than Aβ-Binding Alcohol Dehydrogenase.
    He XY; Dobkin C; Brown WT; Yang SY
    Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37239833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
    He XY; Isaacs C; Yang SY
    J Alzheimers Dis; 2018; 62(2):665-673. PubMed ID: 29480196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro study of interaction of 17β-hydroxysteroid dehydrogenase type 10 and cyclophilin D and its potential implications for Alzheimer's disease.
    Hemmerová E; Špringer T; Krištofiková Z; Homola J
    Sci Rep; 2019 Nov; 9(1):16700. PubMed ID: 31723183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions of 17β-Hydroxysteroid Dehydrogenase Type 10 and Cyclophilin D in Alzheimer's Disease.
    Kristofikova Z; Springer T; Gedeonova E; Hofmannova A; Ricny J; Hromadkova L; Vyhnalek M; Laczo J; Nikolai T; Hort J; Petrasek T; Stuchlik A; Vales K; Klaschka J; Homola J
    Neurochem Res; 2020 Apr; 45(4):915-927. PubMed ID: 31997103
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders.
    Yang SY; He XY; Isaacs C; Dobkin C; Miller D; Philipp M
    J Steroid Biochem Mol Biol; 2014 Sep; 143():460-72. PubMed ID: 25007702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10.
    Aitken L; Quinn SD; Perez-Gonzalez C; Samuel ID; Penedo JC; Gunn-Moore FJ
    Chembiochem; 2016 Jun; 17(11):1029-37. PubMed ID: 26991863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of steroidal derivatives inhibiting the transformations of allopregnanolone and estradiol by 17β-hydroxysteroid dehydrogenase type 10.
    Boutin S; Roy J; Maltais R; Alata W; Calon F; Poirier D
    Bioorg Med Chem Lett; 2018 Dec; 28(22):3554-3559. PubMed ID: 30297283
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity.
    Hanzlova M; Miskerikova MS; Rotterova A; Chalupova K; Jurkova K; Hamsikova M; Andrys R; Haleckova A; Svobodova J; Schmidt M; Benek O; Musilek K
    ACS Med Chem Lett; 2023 Dec; 14(12):1724-1732. PubMed ID: 38116418
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Study of Biomolecular Interactions of Mitochondrial Proteins Related to Alzheimer's Disease: Toward Multi-Interaction Biomolecular Processes.
    Hemmerová E; Špringer T; Krištofiková Z; Homola J
    Biomolecules; 2020 Aug; 10(9):. PubMed ID: 32825572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of 17β-hydroxysteroid dehydrogenase type 10 steroidal inhibitors: Selectivity, metabolic stability and enhanced potency.
    Boutin S; Maltais R; Roy J; Poirier D
    Eur J Med Chem; 2021 Jan; 209():112909. PubMed ID: 33081987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ionic Environment Affects Biomolecular Interactions of Amyloid-β: SPR Biosensor Study.
    Hemmerová E; Špringer T; Krištofiková Z; Homola J
    Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33419257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration.
    Fišar Z; Musílek K; Benek O; Hroch L; Vinklářová L; Schmidt M; Hroudová J; Raboch J
    Toxicol Lett; 2021 Mar; 339():12-19. PubMed ID: 33359020
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.