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3. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations. Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298 [TBL] [Abstract][Full Text] [Related]
4. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Luisier R; Tyzack GE; Hall CE; Mitchell JS; Devine H; Taha DM; Malik B; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R Nat Commun; 2018 May; 9(1):2010. PubMed ID: 29789581 [TBL] [Abstract][Full Text] [Related]
5. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis. Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035 [TBL] [Abstract][Full Text] [Related]
6. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. De Santis R; Alfano V; de Turris V; Colantoni A; Santini L; Garone MG; Antonacci G; Peruzzi G; Sudria-Lopez E; Wyler E; Anink JJ; Aronica E; Landthaler M; Pasterkamp RJ; Bozzoni I; Rosa A Cell Rep; 2019 Jun; 27(13):3818-3831.e5. PubMed ID: 31242416 [TBL] [Abstract][Full Text] [Related]
7. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359 [TBL] [Abstract][Full Text] [Related]
8. Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis. Tyzack GE; Neeves J; Crerar H; Klein P; Ziff O; Taha DM; Luisier R; Luscombe NM; Patani R Brain; 2021 Aug; 144(7):1985-1993. PubMed ID: 33693641 [TBL] [Abstract][Full Text] [Related]
9. Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis. Sabatelli M; Moncada A; Conte A; Lattante S; Marangi G; Luigetti M; Lucchini M; Mirabella M; Romano A; Del Grande A; Bisogni G; Doronzio PN; Rossini PM; Zollino M Hum Mol Genet; 2013 Dec; 22(23):4748-55. PubMed ID: 23847048 [TBL] [Abstract][Full Text] [Related]
10. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons. Harley J; Patani R Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210 [TBL] [Abstract][Full Text] [Related]
11. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging. Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605 [TBL] [Abstract][Full Text] [Related]
12. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Vance C; Rogelj B; Hortobágyi T; De Vos KJ; Nishimura AL; Sreedharan J; Hu X; Smith B; Ruddy D; Wright P; Ganesalingam J; Williams KL; Tripathi V; Al-Saraj S; Al-Chalabi A; Leigh PN; Blair IP; Nicholson G; de Belleroche J; Gallo JM; Miller CC; Shaw CE Science; 2009 Feb; 323(5918):1208-1211. PubMed ID: 19251628 [TBL] [Abstract][Full Text] [Related]
13. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation. Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081 [TBL] [Abstract][Full Text] [Related]
14. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration. Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267 [TBL] [Abstract][Full Text] [Related]
15. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis. Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583 [TBL] [Abstract][Full Text] [Related]
16. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules. Vance C; Scotter EL; Nishimura AL; Troakes C; Mitchell JC; Kathe C; Urwin H; Manser C; Miller CC; Hortobágyi T; Dragunow M; Rogelj B; Shaw CE Hum Mol Genet; 2013 Jul; 22(13):2676-88. PubMed ID: 23474818 [TBL] [Abstract][Full Text] [Related]
17. Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS. Ito D; Suzuki N Neurology; 2011 Oct; 77(17):1636-43. PubMed ID: 21956718 [TBL] [Abstract][Full Text] [Related]
18. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis. Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728 [TBL] [Abstract][Full Text] [Related]
19. Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1. Tibshirani M; Tradewell ML; Mattina KR; Minotti S; Yang W; Zhou H; Strong MJ; Hayward LJ; Durham HD Hum Mol Genet; 2015 Feb; 24(3):773-86. PubMed ID: 25274782 [TBL] [Abstract][Full Text] [Related]
20. FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS. Harley J; Hagemann C; Serio A; Patani R Brain; 2020 Dec; 143(12):e103. PubMed ID: 33253377 [No Abstract] [Full Text] [Related] [Next] [New Search]