422 related articles for article (PubMed ID: 31368616)
1. Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells.
Nishimura N; Radwan MO; Amano M; Endo S; Fujii E; Hayashi H; Ueno S; Ueno N; Tatetsu H; Hata H; Okamoto Y; Otsuka M; Mitsuya H; Matsuoka M; Okuno Y
Cancer Sci; 2019 Oct; 110(10):3275-3287. PubMed ID: 31368616
[TBL] [Abstract][Full Text] [Related]
2. Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells.
Auner HW; Moody AM; Ward TH; Kraus M; Milan E; May P; Chaidos A; Driessen C; Cenci S; Dazzi F; Rahemtulla A; Apperley JF; Karadimitris A; Dillon N
PLoS One; 2013; 8(9):e74415. PubMed ID: 24069311
[TBL] [Abstract][Full Text] [Related]
3. A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells.
Zhang G; Li S; Wang F; Jones AC; Goldberg AFG; Lin B; Virgil S; Stoltz BM; Deshaies RJ; Chou TF
Eur J Med Chem; 2021 Mar; 213():113148. PubMed ID: 33476933
[TBL] [Abstract][Full Text] [Related]
4. Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells.
Kobayashi T; Tanaka K; Inoue K; Kakizuka A
J Biol Chem; 2002 Dec; 277(49):47358-65. PubMed ID: 12351637
[TBL] [Abstract][Full Text] [Related]
5. VCP/p97/Cdc48, A Linking of Protein Homeostasis and Cancer Therapy.
Lan B; Chai S; Wang P; Wang K
Curr Mol Med; 2017; 17(9):608-618. PubMed ID: 29521227
[TBL] [Abstract][Full Text] [Related]
6. AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation.
Zhong X; Shen Y; Ballar P; Apostolou A; Agami R; Fang S
J Biol Chem; 2004 Oct; 279(44):45676-84. PubMed ID: 15331598
[TBL] [Abstract][Full Text] [Related]
7. Interaction between salt-inducible kinase 2 (SIK2) and p97/valosin-containing protein (VCP) regulates endoplasmic reticulum (ER)-associated protein degradation in mammalian cells.
Yang FC; Lin YH; Chen WH; Huang JY; Chang HY; Su SH; Wang HT; Chiang CY; Hsu PH; Tsai MD; Tan BC; Lee SC
J Biol Chem; 2013 Nov; 288(47):33861-33872. PubMed ID: 24129571
[TBL] [Abstract][Full Text] [Related]
8. The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group.
Wang Q; Shinkre BA; Lee JG; Weniger MA; Liu Y; Chen W; Wiestner A; Trenkle WC; Ye Y
PLoS One; 2010 Nov; 5(11):e15479. PubMed ID: 21124757
[TBL] [Abstract][Full Text] [Related]
9. BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation.
Wang Y; Wan B; Zhou J; Li R; Yu L
Biotechnol Lett; 2013 Dec; 35(12):1983-9. PubMed ID: 23907667
[TBL] [Abstract][Full Text] [Related]
10. Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation.
Ballar P; Zhong Y; Nagahama M; Tagaya M; Shen Y; Fang S
J Biol Chem; 2007 Nov; 282(47):33908-14. PubMed ID: 17872946
[TBL] [Abstract][Full Text] [Related]
11. p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity.
Her NG; Toth JI; Ma CT; Wei Y; Motamedchaboki K; Sergienko E; Petroski MD
Cell Chem Biol; 2016 Apr; 23(4):517-28. PubMed ID: 27105284
[TBL] [Abstract][Full Text] [Related]
12. Regulation of ER-associated degradation via p97/VCP-interacting motif.
Ballar P; Fang S
Biochem Soc Trans; 2008 Oct; 36(Pt 5):818-22. PubMed ID: 18793143
[TBL] [Abstract][Full Text] [Related]
13. VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.
Bastola P; Neums L; Schoenen FJ; Chien J
Mol Oncol; 2016 Dec; 10(10):1559-1574. PubMed ID: 27729194
[TBL] [Abstract][Full Text] [Related]
14. Central pore residues mediate the p97/VCP activity required for ERAD.
DeLaBarre B; Christianson JC; Kopito RR; Brunger AT
Mol Cell; 2006 May; 22(4):451-62. PubMed ID: 16713576
[TBL] [Abstract][Full Text] [Related]
15. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways.
Chou TF; Brown SJ; Minond D; Nordin BE; Li K; Jones AC; Chase P; Porubsky PR; Stoltz BM; Schoenen FJ; Patricelli MP; Hodder P; Rosen H; Deshaies RJ
Proc Natl Acad Sci U S A; 2011 Mar; 108(12):4834-9. PubMed ID: 21383145
[TBL] [Abstract][Full Text] [Related]
16. Sequential actions of the AAA-ATPase valosin-containing protein (VCP)/p97 and the proteasome 19 S regulatory particle in sterol-accelerated, endoplasmic reticulum (ER)-associated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Morris LL; Hartman IZ; Jun DJ; Seemann J; DeBose-Boyd RA
J Biol Chem; 2014 Jul; 289(27):19053-66. PubMed ID: 24860107
[TBL] [Abstract][Full Text] [Related]
17. SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism.
Hoang B; Shi Y; Frost PJ; Mysore V; Bardeleben C; Lichtenstein A
Mol Cancer Res; 2016 Apr; 14(4):397-407. PubMed ID: 26869290
[TBL] [Abstract][Full Text] [Related]
18. Disruption of p97/VCP induces autophagosome accumulation, cell cycle arrest and apoptosis in human choriocarcinoma cells.
Desdicioglu R; Sahin C; Yavuz F; Cayli S
Mol Biol Rep; 2021 Mar; 48(3):2163-2171. PubMed ID: 33620660
[TBL] [Abstract][Full Text] [Related]
19. Unconventional p97/VCP-Mediated Endoplasmic Reticulum-to-Endosome Trafficking of a Retroviral Protein.
Xu WK; Gou Y; Lozano MM; Dudley JP
J Virol; 2021 Jun; 95(14):e0053121. PubMed ID: 33952644
[TBL] [Abstract][Full Text] [Related]
20. Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death.
Yi P; Higa A; Taouji S; Bexiga MG; Marza E; Arma D; Castain C; Le Bail B; Simpson JC; Rosenbaum J; Balabaud C; Bioulac-Sage P; Blanc JF; Chevet E
Mol Cancer Ther; 2012 Dec; 11(12):2610-20. PubMed ID: 23041544
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]