BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 31369682)

  • 1. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y; Yang J; Niu L; Hu D; Li H; Chen L; Yu Y; Chen Q
    FEBS Lett; 2020 Jan; 594(1):199-204. PubMed ID: 31369682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New indole-based chalconoids as tubulin-targeting antiproliferative agents.
    Mirzaei H; Shokrzadeh M; Modanloo M; Ziar A; Riazi GH; Emami S
    Bioorg Chem; 2017 Dec; 75():86-98. PubMed ID: 28922629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
    Cheng J; Wu Y; Wang Y; Wang C; Wang Y; Wu C; Zeng S; Yu Y; Chen Q
    Biochem Biophys Res Commun; 2018 Jan; 495(1):185-188. PubMed ID: 29102632
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
    Wang Y; Zhang H; Gigant B; Yu Y; Wu Y; Chen X; Lai Q; Yang Z; Chen Q; Yang J
    FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site.
    Li L; Jiang S; Li X; Liu Y; Su J; Chen J
    Eur J Med Chem; 2018 May; 151():482-494. PubMed ID: 29649743
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
    Coluccia A; Sabbadin D; Brancale A
    Eur J Med Chem; 2011 Aug; 46(8):3519-25. PubMed ID: 21621885
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.
    Niu L; Wang Y; Wang C; Wang Y; Jiang X; Ma L; Wu C; Yu Y; Chen Q
    Biochem Biophys Res Commun; 2017 Nov; 493(1):718-722. PubMed ID: 28864414
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Rationale for Drug Design Provided by Co-Crystal Structure of IC261 in Complex with Tubulin.
    Xian J; Bu F; Wang Y; Long F; Zhang Z; Wu C; Tao Y; Wang T; Wang G
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33579052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New ligands of the tubulin colchicine site based on X-ray structures.
    Álvarez R; Medarde M; Peláez R
    Curr Top Med Chem; 2014; 14(20):2231-52. PubMed ID: 25434358
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fragment based group QSAR and molecular dynamics mechanistic studies on arylthioindole derivatives targeting the α-β interfacial site of human tubulin.
    Tyagi C; Gupta A; Goyal S; Dhanjal J; Grover A
    BMC Genomics; 2014; 15 Suppl 9(Suppl 9):S3. PubMed ID: 25521775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Indole derivatives (2010-2020) as versatile tubulin inhibitors: synthesis and structure-activity relationships.
    Naaz F; Neha K; Haider MR; Shafi S
    Future Med Chem; 2021 Oct; 13(20):1795-1828. PubMed ID: 34468201
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
    Kazan F; Yagci ZB; Bai R; Ozkirimli E; Hamel E; Ozkirimli S
    Comput Biol Chem; 2019 Jun; 80():512-523. PubMed ID: 31185422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K; Sun Z; Zhao F; Shan G; Meng Q
    Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1
    Wang Q; Arnst KE; Wang Y; Kumar G; Ma D; White SW; Miller DD; Li W; Li W
    J Med Chem; 2019 Jul; 62(14):6734-6750. PubMed ID: 31251599
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors.
    El-Sayed NF; El-Hussieny M; Ewies EF; El Shehry MF; Awad HM; Fouad MA
    Drug Dev Res; 2022 Apr; 83(2):485-500. PubMed ID: 34523738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents.
    Patil SA; Patil R; Miller DD
    Future Med Chem; 2012 Oct; 4(16):2085-115. PubMed ID: 23157240
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F; Zhao H; Li D; Chen H; Quan H; Shi X; Lou L; Hu Y
    J Med Chem; 2011 May; 54(9):3200-5. PubMed ID: 21480626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Indole based Tubulin Polymerization Inhibitors: An Update on Recent Developments.
    Sunil D; Kamath PR
    Mini Rev Med Chem; 2016; 16(18):1470-1499. PubMed ID: 27468786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
    Romagnoli R; Prencipe F; Oliva P; Kimatrai Salvador M; Brancale A; Ferla S; Hamel E; Viola G; Bortolozzi R; Persoons L; Balzarini J; Liekens S; Schols D
    Bioorg Chem; 2020 Apr; 97():103665. PubMed ID: 32086053
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents, an update (2013-2015).
    Patil R; Patil SA; Beaman KD; Patil SA
    Future Med Chem; 2016 Jul; 8(11):1291-316. PubMed ID: 27476704
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.