BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 31371933)

  • 1. The cGAS/STING pathway: a sensor of senescence-associated DNA damage and trigger of inflammation in early age-related macular degeneration.
    Wu Y; Wei Q; Yu J
    Clin Interv Aging; 2019; 14():1277-1283. PubMed ID: 31371933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular senescence and senescence-associated secretory phenotype via the cGAS-STING signaling pathway in cancer.
    Loo TM; Miyata K; Tanaka Y; Takahashi A
    Cancer Sci; 2020 Feb; 111(2):304-311. PubMed ID: 31799772
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Senescence in the pathogenesis of age-related macular degeneration.
    Blasiak J
    Cell Mol Life Sci; 2020 Mar; 77(5):789-805. PubMed ID: 31897543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potential of Telomerase in Age-Related Macular Degeneration-Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α.
    Blasiak J; Szczepanska J; Fila M; Pawlowska E; Kaarniranta K
    Int J Mol Sci; 2021 Jul; 22(13):. PubMed ID: 34281248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging.
    Schmitz CRR; Maurmann RM; Guma FTCR; Bauer ME; Barbé-Tuana FM
    Front Immunol; 2023; 14():1132653. PubMed ID: 36926349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration.
    Zou M; Ke Q; Nie Q; Qi R; Zhu X; Liu W; Hu X; Sun Q; Fu JL; Tang X; Liu Y; Li DW; Gong L
    Cell Death Differ; 2022 Sep; 29(9):1816-1833. PubMed ID: 35347235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer.
    Li T; Chen ZJ
    J Exp Med; 2018 May; 215(5):1287-1299. PubMed ID: 29622565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration.
    Ottone OK; Kim CJ; Collins JA; Risbud MV
    Front Immunol; 2022; 13():882407. PubMed ID: 35769461
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
    Blasiak J; Piechota M; Pawlowska E; Szatkowska M; Sikora E; Kaarniranta K
    Oxid Med Cell Longev; 2017; 2017():5293258. PubMed ID: 29225722
    [TBL] [Abstract][Full Text] [Related]  

  • 10. cGAS-STING drives ageing-related inflammation and neurodegeneration.
    Gulen MF; Samson N; Keller A; Schwabenland M; Liu C; Glück S; Thacker VV; Favre L; Mangeat B; Kroese LJ; Krimpenfort P; Prinz M; Ablasser A
    Nature; 2023 Aug; 620(7973):374-380. PubMed ID: 37532932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids.
    Aguado J; Chaggar HK; Gómez-Inclán C; Shaker MR; Leeson HC; Mackay-Sim A; Wolvetang EJ
    Aging Cell; 2021 Sep; 20(9):e13468. PubMed ID: 34459078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterochromatin inhibits cGAS and STING during oxidative stress-induced retinal pigment epithelium and retina degeneration.
    Zou M; Gong L; Ke Q; Qi R; Zhu X; Liu W; Sun Q; Tang X; Luo Z; Gong X; Liu Y; Li DW
    Free Radic Biol Med; 2022 Jan; 178():147-160. PubMed ID: 34875339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress-induced senescence.
    Han X; Chen H; Gong H; Tang X; Huang N; Xu W; Tai H; Zhang G; Zhao T; Gong C; Wang S; Yang Y; Xiao H
    J Biol Chem; 2020 Apr; 295(14):4451-4463. PubMed ID: 32047109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells.
    Ren C; Jin J; Li C; Xiang J; Wu Y; Zhou Y; Sun L; Zhang X; Tian N
    J Cell Sci; 2022 Aug; 135(15):. PubMed ID: 35722742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration.
    Ferrington DA; Kapphahn RJ; Leary MM; Atilano SR; Terluk MR; Karunadharma P; Chen GK; Ratnapriya R; Swaroop A; Montezuma SR; Kenney MC
    Exp Eye Res; 2016 Apr; 145():269-277. PubMed ID: 26854823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The cGAS-STING pathway in diabetic retinopathy and age-related macular degeneration.
    Hu B; Ma JX; Duerfeldt AS
    Future Med Chem; 2023 Apr; 15(8):717-729. PubMed ID: 37166075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular mechanisms and cellular functions of cGAS-STING signalling.
    Hopfner KP; Hornung V
    Nat Rev Mol Cell Biol; 2020 Sep; 21(9):501-521. PubMed ID: 32424334
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage.
    Zhu X; Liu W; Tang X; Chen Y; Ge X; Ke Q; Liang X; Gan Y; Zheng Y; Zou M; Deng M; Liu Y; Li DW; Gong L
    J Neuroinflammation; 2023 May; 20(1):119. PubMed ID: 37217935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cGAS is essential for cellular senescence.
    Yang H; Wang H; Ren J; Chen Q; Chen ZJ
    Proc Natl Acad Sci U S A; 2017 Jun; 114(23):E4612-E4620. PubMed ID: 28533362
    [TBL] [Abstract][Full Text] [Related]  

  • 20. YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING.
    Sladitschek-Martens HL; Guarnieri A; Brumana G; Zanconato F; Battilana G; Xiccato RL; Panciera T; Forcato M; Bicciato S; Guzzardo V; Fassan M; Ulliana L; Gandin A; Tripodo C; Foiani M; Brusatin G; Cordenonsi M; Piccolo S
    Nature; 2022 Jul; 607(7920):790-798. PubMed ID: 35768505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.