BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 31374128)

  • 1. Bioactivation mechanisms of N-hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids.
    Okuno Y; Bonala R; Attaluri S; Johnson F; Grollman AP; Sidorenko VS; Oda Y
    Environ Mol Mutagen; 2019 Dec; 60(9):792-806. PubMed ID: 31374128
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.
    Hashimoto K; Zaitseva IN; Bonala R; Attaluri S; Ozga K; Iden CR; Johnson F; Moriya M; Grollman AP; Sidorenko VS
    Carcinogenesis; 2016 Jul; 37(7):647-655. PubMed ID: 27207664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.
    Martinek V; Kubickova B; Arlt VM; Frei E; Schmeiser HH; Hudecek J; Stiborova M
    Neuro Endocrinol Lett; 2011; 32 Suppl 1():57-70. PubMed ID: 22167209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase.
    Arlt VM; Glatt H; Muckel E; Pabel U; Sorg BL; Schmeiser HH; Phillips DH
    Carcinogenesis; 2002 Nov; 23(11):1937-45. PubMed ID: 12419844
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.
    Arlt VM; Glatt H; Muckel E; Pabel U; Sorg BL; Seidel A; Frank H; Schmeiser HH; Phillips DH
    Int J Cancer; 2003 Jul; 105(5):583-92. PubMed ID: 12740904
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bioactivation of the human carcinogen aristolochic acid.
    Sidorenko VS; Attaluri S; Zaitseva I; Iden CR; Dickman KG; Johnson F; Grollman AP
    Carcinogenesis; 2014 Aug; 35(8):1814-22. PubMed ID: 24743514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases.
    Stiborová M; Mareš J; Frei E; Arlt VM; Martínek V; Schmeiser HH
    Environ Mol Mutagen; 2011 Jul; 52(6):448-59. PubMed ID: 21370283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
    Oda Y; Watanabe T; Terao Y; Nukaya H; Wakabayashi K
    Mutat Res; 2008 Jun; 654(1):52-7. PubMed ID: 18562244
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heterologous expression of human N-acetyltransferases 1 and 2 and sulfotransferase 1A1 in Salmonella typhimurium for mutagenicity testing of heterocyclic amines.
    Muckel E; Frandsen H; Glatt HR
    Food Chem Toxicol; 2002 Aug; 40(8):1063-8. PubMed ID: 12067565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation.
    Al-Buheissi SZ; Patel HR; Meinl W; Hewer A; Bryan RL; Glatt H; Miller RA; Phillips DH
    Pharmacogenet Genomics; 2006 Jun; 16(6):391-9. PubMed ID: 16708048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.
    Arlt VM; Stiborova M; Henderson CJ; Osborne MR; Bieler CA; Frei E; Martinek V; Sopko B; Wolf CR; Schmeiser HH; Phillips DH
    Cancer Res; 2005 Apr; 65(7):2644-52. PubMed ID: 15805261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
    Glatt H; Pabel U; Meinl W; Frederiksen H; Frandsen H; Muckel E
    Carcinogenesis; 2004 May; 25(5):801-7. PubMed ID: 14729582
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genotoxic activation of the environmental pollutant 3,6-dinitrobenzo[e]pyrene in Salmonella typhimurium umu strains expressing human cytochrome P450 and N-acetyltransferase.
    Oda Y; Hirayama T; Watanabe T
    Toxicol Lett; 2009 Aug; 188(3):258-62. PubMed ID: 19393727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
    Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.
    Arlt VM; Meinl W; Florian S; Nagy E; Barta F; Thomann M; Mrizova I; Krais AM; Liu M; Richards M; Mirza A; Kopka K; Phillips DH; Glatt H; Stiborova M; Schmeiser HH
    Arch Toxicol; 2017 Apr; 91(4):1957-1975. PubMed ID: 27557898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue.
    Meinl W; Pabel U; Osterloh-Quiroz M; Hengstler JG; Glatt H
    Int J Cancer; 2006 Mar; 118(5):1090-7. PubMed ID: 16161050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.
    Oda Y; Totsuka Y; Wakabayashi K; Guengerich FP; Shimada T
    Mutagenesis; 2006 Nov; 21(6):411-6. PubMed ID: 17067997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system.
    Oda Y
    Mutat Res; 2004 Oct; 554(1-2):399-406. PubMed ID: 15450435
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods.
    Herrmann K; Engst W; Appel KE; Monien BH; Glatt H
    Mutagenesis; 2012 Jul; 27(4):453-62. PubMed ID: 22337896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
    Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
    Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.