BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 31374199)

  • 1. Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A.
    Cardenas-Diaz FL; Osorio-Quintero C; Diaz-Miranda MA; Kishore S; Leavens K; Jobaliya C; Stanescu D; Ortiz-Gonzalez X; Yoon C; Chen CS; Haliyur R; Brissova M; Powers AC; French DL; Gadue P
    Cell Stem Cell; 2019 Aug; 25(2):273-289.e5. PubMed ID: 31374199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship between mutation position and clinical phenotype in monogenic diabetes.
    Harries LW; Ellard S; Stride A; Morgan NG; Hattersley AT
    Hum Mol Genet; 2006 Jul; 15(14):2216-24. PubMed ID: 16760222
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells.
    Low BSJ; Lim CS; Ding SSL; Tan YS; Ng NHJ; Krishnan VG; Ang SF; Neo CWY; Verma CS; Hoon S; Lim SC; Tai ES; Teo AKK
    Nat Commun; 2021 May; 12(1):3133. PubMed ID: 34035238
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The spectrum of HNF1A gene mutations in Greek patients with MODY3: relative frequency and identification of seven novel germline mutations.
    Tatsi C; Kanaka-Gantenbein C; Vazeou-Gerassimidi A; Chrysis D; Delis D; Tentolouris N; Dacou-Voutetakis C; Chrousos GP; Sertedaki A
    Pediatr Diabetes; 2013 Nov; 14(7):526-34. PubMed ID: 23517481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-function studies of HNF1A (MODY3) gene mutations in South Indian patients with monogenic diabetes.
    Balamurugan K; Bjørkhaug L; Mahajan S; Kanthimathi S; Njølstad PR; Srinivasan N; Mohan V; Radha V
    Clin Genet; 2016 Dec; 90(6):486-495. PubMed ID: 26853433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HNF1A:From Monogenic Diabetes to Type 2 Diabetes and Gestational Diabetes Mellitus.
    Li LM; Jiang BG; Sun LL
    Front Endocrinol (Lausanne); 2022; 13():829565. PubMed ID: 35299962
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells.
    Yabe SG; Nishida J; Fukuda S; Takeda F; Nasiro K; Yasuda K; Iwasaki N; Okochi H
    PLoS One; 2019; 14(5):e0217110. PubMed ID: 31145732
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage.
    Jeannot E; Mellottee L; Bioulac-Sage P; Balabaud C; Scoazec JY; Tran Van Nhieu J; Bacq Y; Michalak S; Buob D; ; Laurent-Puig P; Rusyn I; Zucman-Rossi J
    Diabetes; 2010 Jul; 59(7):1836-44. PubMed ID: 20393147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential effects of HNF-1α mutations associated with familial young-onset diabetes on target gene regulation.
    Galán M; García-Herrero CM; Azriel S; Gargallo M; Durán M; Gorgojo JJ; Andía VM; Navas MA
    Mol Med; 2011; 17(3-4):256-65. PubMed ID: 21170474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tubular proteinuria in patients with HNF1α mutations: HNF1α drives endocytosis in the proximal tubule.
    Terryn S; Tanaka K; Lengelé JP; Olinger E; Dubois-Laforgue D; Garbay S; Kozyraki R; Van Der Smissen P; Christensen EI; Courtoy PJ; Bellanné-Chantelot C; Timsit J; Pontoglio M; Devuyst O
    Kidney Int; 2016 May; 89(5):1075-1089. PubMed ID: 27083284
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HNF1A-MODY Mutations in Nuclear Localization Signal Impair HNF1A-Import Receptor KPNA6 Interactions.
    Fareed FMA; Korulu S; Özbil M; Çapan ÖY
    Protein J; 2021 Aug; 40(4):512-521. PubMed ID: 33459938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An intron mutation of HNF1A causes abnormal splicing and impairs its activity as a transcription factor.
    Wang M; Shu H; Xie J; Huang Y; Wang K; Feng R; Yu X; Guan J; Feng W; Liu M
    Mol Cell Endocrinol; 2022 Apr; 545():111575. PubMed ID: 35081418
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduced pancreatic volume in hepatocyte nuclear factor 1A-maturity-onset diabetes of the young.
    Vesterhus M; Haldorsen IS; Raeder H; Molven A; Njølstad PR
    J Clin Endocrinol Metab; 2008 Sep; 93(9):3505-9. PubMed ID: 18593771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 3 (MODY3) carrying a hepatocyte nuclear factor 1-alpha (HNF1A) mutation.
    Griscelli F; Ezanno H; Soubeyrand M; Feraud O; Oudrhiri N; Bonnefond A; Turhan AG; Froguel P; Bennaceur-Griscelli A
    Stem Cell Res; 2018 May; 29():56-59. PubMed ID: 29597128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional characterization of p.Pro409His variant in HNF1A, a hypomorphic mutation involved in pancreatic β-cell dysfunction.
    Nocera D; Menniti M; Belviso S; Bond HM; Lanzillotta D; Spoleti CB; Guagliardi MR; Malatesta P; Trapasso F; Irace C; Perrotti N; Iuliano R
    Acta Diabetol; 2019 Aug; 56(8):883-888. PubMed ID: 30963309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defective functions of HNF1A variants on BCL2L1 transactivation and beta-cell growth.
    Sujjitjoon J; Charoensuk C; Thanyaphon T; Kooptiwut S; Thamtarana PJ; Tangjittipokin W; Chongjaroen N; Chanprasert C; Abubakar Z; Lapbenjakul S; Yenchitsomanus PT; Plengvidhya N
    Biochem Biophys Res Commun; 2020 Aug; 529(3):826-833. PubMed ID: 32684311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intima-media thickness and endothelial dysfunction in GCK and HNF1A-MODY patients.
    Szopa M; Osmenda G; Wilk G; Matejko B; Skupien J; Zapala B; Młynarski W; Guzik T; Malecki MT
    Eur J Endocrinol; 2015 Mar; 172(3):277-83. PubMed ID: 25501962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel presentations of congenital hyperinsulinism due to mutations in the MODY genes: HNF1A and HNF4A.
    Stanescu DE; Hughes N; Kaplan B; Stanley CA; De León DD
    J Clin Endocrinol Metab; 2012 Oct; 97(10):E2026-30. PubMed ID: 22802087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.
    González BJ; Zhao H; Niu J; Williams DJ; Lee J; Goulbourne CN; Xing Y; Wang Y; Oberholzer J; Blumenkrantz MH; Chen X; LeDuc CA; Chung WK; Colecraft HM; Gromada J; Shen Y; Goland RS; Leibel RL; Egli D
    Commun Biol; 2022 Aug; 5(1):779. PubMed ID: 35918471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Liver adenomatosis in patients with hepatocyte nuclear factor-1 alpha maturity onset diabetes of the young (HNF1A-MODY): Clinical, radiological and pathological characteristics in a French series.
    Haddouche A; Bellanne-Chantelot C; Rod A; Fournier L; Chiche L; Gautier JF; Timsit J; Laboureau S; Chaillous L; Valero R; Larger E; Jeandidier N; Wilhelm JM; Popelier M; Guillausseau PJ; Thivolet C; Lecomte P; Benhamou PY; Reznik Y
    J Diabetes; 2020 Jan; 12(1):48-57. PubMed ID: 31166087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.