BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 31379128)

  • 1. Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.
    Schuler F; Afreen S; Manzl C; Häcker G; Erlacher M; Villunger A
    EMBO Rep; 2019 Aug; 20(8):e47026. PubMed ID: 31379128
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells.
    Xie Y; Koch ML; Zhang X; Hamblen MJ; Godinho FJ; Fujiwara Y; Xie H; Klusmann JH; Orkin SH; Li Z
    Stem Cells; 2017 Jul; 35(7):1773-1785. PubMed ID: 28436588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53.
    Valente LJ; Grabow S; Vandenberg CJ; Strasser A; Janic A
    Oncogene; 2016 Jul; 35(29):3866-71. PubMed ID: 26640149
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.
    Gao L; Li D; Ma K; Zhang W; Xu T; Fu C; Jing C; Jia X; Wu S; Sun X; Dong M; Deng M; Chen Y; Zhu W; Peng J; Wan F; Zhou Y; Zon LI; Pan W
    PLoS Genet; 2015 Jul; 11(7):e1005346. PubMed ID: 26131719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells.
    Ando K; Nakamura Y; Nagase H; Nakagawara A; Koshinaga T; Wada S; Makishima M
    Int J Mol Sci; 2019 Jul; 20(15):. PubMed ID: 31362335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The SKP2-p27 axis defines susceptibility to cell death upon CHK1 inhibition.
    Lohmüller M; Roeck BF; Szabo TG; Schapfl MA; Pegka F; Herzog S; Villunger A; Schuler F
    Mol Oncol; 2022 Aug; 16(15):2771-2787. PubMed ID: 35673965
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of Irf5 protects hematopoietic stem cells from DNA damage-induced apoptosis and suppresses γ-irradiation-induced thymic lymphomagenesis.
    Bi X; Feng D; Korczeniewska J; Alper N; Hu G; Barnes BJ
    Oncogene; 2014 Jun; 33(25):3288-97. PubMed ID: 23912454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.
    Belle JI; Petrov JC; Langlais D; Robert F; Cencic R; Shen S; Pelletier J; Gros P; Nijnik A
    Cell Death Differ; 2016 May; 23(5):759-75. PubMed ID: 26768662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death.
    Del Nagro CJ; Choi J; Xiao Y; Rangell L; Mohan S; Pandita A; Zha J; Jackson PK; O'Brien T
    Cell Cycle; 2014; 13(2):303-14. PubMed ID: 24247149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
    Valente LJ; Gray DH; Michalak EM; Pinon-Hofbauer J; Egle A; Scott CL; Janic A; Strasser A
    Cell Rep; 2013 May; 3(5):1339-45. PubMed ID: 23665218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.
    Valente LJ; Aubrey BJ; Herold MJ; Kelly GL; Happo L; Scott CL; Newbold A; Johnstone RW; Huang DC; Vassilev LT; Strasser A
    Cell Rep; 2016 Mar; 14(8):1858-66. PubMed ID: 26904937
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.
    Guirguis AA; Slape CI; Failla LM; Saw J; Tremblay CS; Powell DR; Rossello F; Wei A; Strasser A; Curtis DJ
    Cell Death Differ; 2016 Jun; 23(6):1049-59. PubMed ID: 26742432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.
    Michalak EM; Vandenberg CJ; Delbridge AR; Wu L; Scott CL; Adams JM; Strasser A
    Genes Dev; 2010 Aug; 24(15):1608-13. PubMed ID: 20679396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer.
    Doerr F; George J; Schmitt A; Beleggia F; Rehkämper T; Hermann S; Walter V; Weber JP; Thomas RK; Wittersheim M; Büttner R; Persigehl T; Reinhardt HC
    Sci Rep; 2017 Nov; 7(1):15511. PubMed ID: 29138515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma.
    Wu WS; Heinrichs S; Xu D; Garrison SP; Zambetti GP; Adams JM; Look AT
    Cell; 2005 Nov; 123(4):641-53. PubMed ID: 16286009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment.
    Brown A; Pospiech J; Eiwen K; Baker DJ; Moehrle B; Sakk V; Nattamai K; Vogel M; Grigoryan A; Geiger H
    Stem Cell Reports; 2017 Nov; 9(5):1359-1368. PubMed ID: 29056333
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
    Duan L; Perez RE; Hansen M; Gitelis S; Maki CG
    Cancer Biol Ther; 2014; 15(12):1600-12. PubMed ID: 25482935
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury.
    Aubrecht TG; Faden AI; Sabirzhanov B; Glaser EP; Roelofs BA; Polster BM; Makarevich O; Stoica BA
    Cell Death Dis; 2018 Nov; 9(11):1121. PubMed ID: 30401820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.