BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 31381192)

  • 1. Design and synthesis of leucine-linked quinazoline-4(3H)-one-sulphonamide molecules distorting malarial reductase activity in the folate pathway.
    Patel TS; Bhatt JD; Dixit RB; Chudasama CJ; Patel BD; Dixit BC
    Arch Pharm (Weinheim); 2019 Sep; 352(9):e1900099. PubMed ID: 31381192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Green synthesis, biological evaluation, molecular docking studies and 3D-QSAR analysis of novel phenylalanine linked quinazoline-4(3H)-one-sulphonamide hybrid entities distorting the malarial reductase activity in folate pathway.
    Patel TS; Bhatt JD; Dixit RB; Chudasama CJ; Patel BD; Dixit BC
    Bioorg Med Chem; 2019 Aug; 27(16):3574-3586. PubMed ID: 31272837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel 2,3-disubstituted quinazoline-4(3H)-one molecules derived from amino acid linked sulphonamide as a potent malarial antifolates for DHFR inhibition.
    Patel TS; Vanparia SF; Patel UH; Dixit RB; Chudasama CJ; Patel BD; Dixit BC
    Eur J Med Chem; 2017 Mar; 129():251-265. PubMed ID: 28231522
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ionic liquid mediated stereoselective synthesis of alanine linked hybrid quinazoline-4(3H)-one derivatives perturbing the malarial reductase activity in folate pathway.
    Patel TS; Bhatt JD; Vanparia SF; Patel UH; Dixit RB; Chudasama CJ; Patel BD; Dixit BC
    Bioorg Med Chem; 2017 Dec; 25(24):6635-6646. PubMed ID: 29126742
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microwave Assisted Synthesis of Pyrimidines in Ionic Liquid and Their Potency as Non-Classical Malarial Antifolates.
    Bhatt JD; Chudasama CJ; Patel KD
    Arch Pharm (Weinheim); 2016 Oct; 349(10):791-800. PubMed ID: 27528517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diarylpyrazole Ligated Dihydropyrimidine Hybrids as Potent Non-Classical Antifolates and Their Efficacy Against Plasmodium falciparum.
    Bhatt JD; Chudasama CJ; Patel KD
    Arch Pharm (Weinheim); 2017 Sep; 350(9):. PubMed ID: 28796406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor.
    Sahu S; Ghosh SK; Gahtori P; Pratap Singh U; Bhattacharyya DR; Bhat HR
    Pharmacol Rep; 2019 Oct; 71(5):762-767. PubMed ID: 31351317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities.
    Thakkar SS; Thakor P; Ray A; Doshi H; Thakkar VR
    Bioorg Med Chem; 2017 Oct; 25(20):5396-5406. PubMed ID: 28789907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, Plasmodium falciparum Inhibitory Activity, Cytotoxicity and Solubility of N2 ,N4 -Disubstituted Quinazoline-2,4-diamines.
    Pobsuk N; Suphakun P; Hannongbua S; Nantasenamat C; Choowongkomon K; Gleeson MP
    Med Chem; 2019; 15(6):693-704. PubMed ID: 30569870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Novel Series of [1,2,4]Triazolo[4,3-a]Pyridine Sulfonamides as Potential Antimalarial Agents: In Silico Studies, Synthesis and In Vitro Evaluation.
    Karpina VR; Kovalenko SS; Kovalenko SM; Drushlyak OG; Bunyatyan ND; Georgiyants VA; Ivanov VV; Langer T; Maes L
    Molecules; 2020 Sep; 25(19):. PubMed ID: 33007887
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates.
    Bhattacharjee AK; Hartell MG; Nichols DA; Hicks RP; Stanton B; van Hamont JE; Milhous WK
    Eur J Med Chem; 2004 Jan; 39(1):59-67. PubMed ID: 14987834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring QSAR, pharmacophore mapping and docking studies and virtual library generation for cycloguanil derivatives as PfDHFR-TS inhibitors.
    Ojha PK; Roy K
    Med Chem; 2011 May; 7(3):173-99. PubMed ID: 21486210
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities.
    Thakkar SS; Thakor P; Doshi H; Ray A
    Bioorg Med Chem; 2017 Aug; 25(15):4064-4075. PubMed ID: 28634040
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 5-arylfuro[2,3-d]pyrimidines as novel dihydrofolate reductase inhibitors.
    Wahid F; Monneret C; Dauzonne D
    Chem Pharm Bull (Tokyo); 1999 Feb; 47(2):156-64. PubMed ID: 10071850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors.
    Kumar Singh A; Rajendran V; Singh S; Kumar P; Kumar Y; Singh A; Miller W; Potemkin V; Poonam ; Grishina M; Gupta N; Kempaiah P; Durvasula R; Singh BK; Dunn BM; Rathi B
    Bioorg Med Chem; 2018 Jul; 26(13):3837-3844. PubMed ID: 29983285
    [TBL] [Abstract][Full Text] [Related]  

  • 16. QSAR, docking and ADMET studies of artemisinin derivatives for antimalarial activity targeting plasmepsin II, a hemoglobin-degrading enzyme from P. falciparum.
    Qidwai T; Yadav DK; Khan F; Dhawan S; Bhakuni RS
    Curr Pharm Des; 2012; 18(37):6133-54. PubMed ID: 22670592
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3D QSAR, pharmacophore and molecular docking studies of known inhibitors and designing of novel inhibitors for M18 aspartyl aminopeptidase of Plasmodium falciparum.
    Kumari M; Chandra S; Tiwari N; Subbarao N
    BMC Struct Biol; 2016 Aug; 16():12. PubMed ID: 27534744
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum.
    Tarnchompoo B; Sirichaiwat C; Phupong W; Intaraudom C; Sirawaraporn W; Kamchonwongpaisan S; Vanichtanankul J; Thebtaranonth Y; Yuthavong Y
    J Med Chem; 2002 Mar; 45(6):1244-52. PubMed ID: 11881993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, Biological Evaluation, and Molecular Modeling Studies of Chiral Chloroquine Analogues as Antimalarial Agents.
    Kondaparla S; Debnath U; Soni A; Dola VR; Sinha M; Srivastava K; Puri SK; Katti SB
    Antimicrob Agents Chemother; 2018 Dec; 62(12):. PubMed ID: 30224532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 3D-QSAR, molecular docking, DFT and ADMET studies on quinazoline derivatives to explore novel DHFR inhibitors.
    Hadni H; Bakhouch M; Elhallaoui M
    J Biomol Struct Dyn; 2023 Jan; 41(1):161-175. PubMed ID: 34825630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.